Discovering Tuberculosis
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Discovering Tuberculosis
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Author : Christian W. McMillen
language : en
Publisher: Yale University Press
Release Date : 2015-01-01
Discovering Tuberculosis written by Christian W. McMillen and has been published by Yale University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-01 with History categories.
Tuberculosis is one of the world's deadliest infectious diseases, killing nearly two million people every year, now more than at any other time in history. While the developed world has nearly forgotten about TB, it continues to wreak havoc across much of the globe. In this interdisciplinary study of global efforts to control TB, Christian McMillen examines the disease's remarkable staying power by offering a probing look at key locations, developments, ideas, and medical successes and failures since 1900. He explores TB and race in east Africa, in South Africa, and on Native American reservations in the first half of the twentieth century, investigates the unsuccessful search for a vaccine, uncovers the origins of drug-resistant tuberculosis in Kenya and elsewhere in the decades following World War II, and details the tragic story of the resurgence of TB in the era of HIV/AIDS. Discovering Tuberculosis tells the story of why controlling TB has been, and continues to be, so difficult.
The New Profile Of Drug Resistant Tuberculosis In Russia
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Author : Russian Academy of Medical Sciences
language : en
Publisher: National Academies Press
Release Date : 2011-08-07
The New Profile Of Drug Resistant Tuberculosis In Russia written by Russian Academy of Medical Sciences and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-07 with Medical categories.
An estimated 2 billion people, one third of the global population, are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Spread through the air, this infectious disease killed 1.7 million in 2009, and is the leading killer of people with HIV. Tuberculosis (TB) is also a disease of poverty-the vast majority of tuberculosis deaths occur in the developing world. Exacerbating the devastation caused by TB is the growing threat of drug-resistant forms of the disease in many parts of the world. Drug-resistant tuberculosis presents a number of significant challenges in terms of controlling its spread, diagnosing patients quickly and accurately, and using drugs to treat patients effectively. In Russia in recent decades, the rise of these strains of TB, resistant to standard antibiotic treatment, has been exacerbated by the occurrence of social, political, and economic upheavals. The Institute of Medicine (IOM) Forum on Drug Discovery, Development, and Translation, in conjunction with the Russian Academy of Medical Sciences held a workshop to discuss ways to fight the growing threat of drug-resistant TB. The New Profile of Drug-Resistant Tuberculosis in Russia: A Global and Local Perspective: Summary of a Joint Workshop presents information from experts on the nature of this threat and how it can be addressed by exploring various treatment and diagnostic options.
Facing The Reality Of Drug Resistant Tuberculosis In India
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-08-20
Facing The Reality Of Drug Resistant Tuberculosis In India written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-20 with Medical categories.
An estimated 8.8 million people fell ill with tuberculosis (TB) in 2010 and 1.4 million died from the disease. Although antibiotics to treat TB were developed in the 1950s and are effective against a majority of TB cases, resistance to these antibiotics has emerged over the years, resulting in the growing spread of multidrug-resistant (MDR) TB. Due to challenges in timely and accurate diagnosis of drug-resistant TB, length and tolerability of treatment regimens, and expense of second-line anti-TB drugs, effectively controlling the disease requires complex public health interventions. The IOM Forum on Drug Discovery, Development, and Translation held three international workshops to gather information from local experts around the world on the threat of drug resistant TB and how the challenges it presents can be met. Workshops were held in South Africa and Russia in 2010. The third workshop was held April 18-19, 2011, in New Delhi, India, in collaboration with the Indian National Science Academy and the Indian Council of Medical Research. The aim of the workshop was to highlight key challenges to controlling the spread of drug-resistant strains of TB in India and to discuss strategies for advancing and integrating local and international efforts to prevent and treat drug-resistant TB. This document summarizes the workshop.
Tuberculosis
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Author : Frank Ryan
language : en
Publisher: FPR-Books Ltd
Release Date : 1992
Tuberculosis written by Frank Ryan and has been published by FPR-Books Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Tuberculosis categories.
Tuberculosis is the greatest killer of all time. In this century and the previous one, it was responsible for the deaths of a thousand million human beings. Half way through the 20th century, people did not believe that a cure would ever be possible, but a few scientists throughout the world each played a part in finding that cure. The discovery changed history, yet that story has never been told.
Tuberculosis In Adults And Children
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Author : Dorothee Heemskerk
language : en
Publisher: Springer
Release Date : 2015-07-17
Tuberculosis In Adults And Children written by Dorothee Heemskerk and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-17 with Medical categories.
This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Disease Control Priorities Third Edition Volume 6
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Author : King K. Holmes
language : en
Publisher: World Bank Publications
Release Date : 2017-11-06
Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-06 with Medical categories.
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
The Global Crisis Of Drug Resistant Tuberculosis And Leadership Of China And The Brics
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2014-03-28
The Global Crisis Of Drug Resistant Tuberculosis And Leadership Of China And The Brics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-28 with Medical categories.
Multidrug-resistant tuberculosis (TB) is caused by bacteria resistant to isoniazid and rifampicin, the two most effective first-line anti-TB drugs, originally developed and introduced in the 1950 and 1960s. Since 2008, the Forum on Drug Discovery, Development, and Translation of the Institute of Medicine has hosted or co-hosted six domestic and international workshops addressing the global crisis of drug-resistant TB, with special attention to the BRICS countries - Brazil, Russia, India, China, and South Africa. The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS is the summary of a workshop convened to address the current status of drug-resistant TB globally and in China. This report considers lessons learned from high burden countries; highlights global challenges to controlling the spread of drug-resistant strains; and discusses innovative strategies to advance and harmonize local and international efforts to prevent and treat drug-resistant TB. Additionally, the report examines the problem of MDR TB and emergent TB strains that are potentially untreatable with drugs available and considers the critical leadership role of the BRICS countries in addressing the threats and opportunities in drug-resistant TB.
Exploring Immune Variability In Susceptibility To Tuberculosis Infection In Humans
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Author : Julie G. Burel
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-16
Exploring Immune Variability In Susceptibility To Tuberculosis Infection In Humans written by Julie G. Burel and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-16 with Medical categories.
Catching Breath
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Author : Kathryn Lougheed
language : en
Publisher: Bloomsbury Publishing
Release Date : 2017-09-05
Catching Breath written by Kathryn Lougheed and has been published by Bloomsbury Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-05 with Health & Fitness categories.
A biography of tuberculosis, an ancient disease--but still a present danger.
Understanding The Pathogenesis Of Tuberculosis T B For The Discovery Of New Therapeutic Targets At Molecular Level Recent Perspectives For An Old Disease
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Author : Dr.Hakim Saboowala
language : en
Publisher: Dr.Hakim Saboowala
Release Date : 2020-07-06
Understanding The Pathogenesis Of Tuberculosis T B For The Discovery Of New Therapeutic Targets At Molecular Level Recent Perspectives For An Old Disease written by Dr.Hakim Saboowala and has been published by Dr.Hakim Saboowala this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-06 with Medical categories.
Understanding the Pathogenesis of Tuberculosis (T.B.) for the Discovery of New Therapeutic Targets at Molecular Level: Recent Perspectives for an Old Disease. The history of tuberculosis (TB) mixtures with the history of humanity since TB is one of the oldest infectious diseases affecting mankind. Bone TB was identified in 4000 years old skeletons, from Europe and Middle East, as the cause of death. Tuberculosis is an ancient infectious disease that remains a threat for public health around the world. Although the etiological agent as well as tuberculosis pathogenesis is well known, the molecular mechanisms underlying the host defense to the bacilli remain elusive. An attempt has been made in this Booklet to focus on the innate immunity of this disease reviewing: 1. Well-established and consensual mechanisms like: o Mycobacterium tuberculosis interference with phagosome maturation, Less consensual mechanism like: o Nitric oxide production, and 3. New mechanisms, such as: o Mycobacteria translocation to the cytosol, o Autophagy, and Apoptosis/Necrosis proposed mainly during the last decade. …Dr. H. K. Saboowala. M.B.(Bom). M. R. S. H. (London).