The Evolution Of Aging
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The Evolution Of Aging
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Author : Theodore C. Goldsmith
language : en
Publisher: Azinet
Release Date : 2006
The Evolution Of Aging written by Theodore C. Goldsmith and has been published by Azinet this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Aging categories.
Goldsmith provides a historical review of biological aging theories including underlying evolution and genetics issues and describes exciting recent discoveries and new theories that are causing renewed interest in aging-by-design.
Evolutionary Biology Of Aging
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Author : Michael R. Rose
language : en
Publisher: Oxford University Press
Release Date : 1994-10-27
Evolutionary Biology Of Aging written by Michael R. Rose and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-27 with Science categories.
This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.
Conceptual Breakthroughs In The Evolutionary Biology Of Aging
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Author : Kenneth R. Arnold
language : en
Publisher: Academic Press
Release Date : 2023-07-10
Conceptual Breakthroughs In The Evolutionary Biology Of Aging written by Kenneth R. Arnold and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Science categories.
Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field’s breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field.The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures. Reviews cell-molecular theories of aging in the light of evolutionary biology Offers an evolutionary analysis of prospects for mitigating aging not commonly discussed within private and public sectors Provides readers with a radically different perspective on contemporary biological gerontology, specifically through the lens of evolutionary biology
The Evolution Of Aging
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Author : Theodore Goldsmith
language : en
Publisher: iUniverse
Release Date : 2003-06-16
The Evolution Of Aging written by Theodore Goldsmith and has been published by iUniverse this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-16 with Aging categories.
Is aging, as most people think, a fundamental, totally unalterable, fact of life? Or is aging actually similar to a universal, but potentially highly treatable, genetic disease? Darwin's dilemma, a little known quirk of the theory of evolution, has for more than 140 years led scientists toward considering aging as inescapable, but recent discoveries and new theoretical work indicate that major medical intervention in the aging process may in fact be possible in the relatively near future. The author takes us on a fascinating tour of the evolution of aging theories from Darwin to the present and includes descriptions of various discoveries and biological oddities that strongly suggest that aging is a treatable condition. The most serious obstacle to the development of anti-aging medicine may be public opinion. A former NASA "rocket scientist", the author provides an outsider's viewpoint, understandable writing, and penetrating logical analysis to the often arcane and tradition-bound world of aging theory.
Genetics And Evolution Of Aging
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Author : Michael R. Rose
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Genetics And Evolution Of Aging written by Michael R. Rose and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Aging is one of those subjects that many biologists feel is largely unknown. Therefore, they often feel comfortable offering extremely facile generalizations that are either unsupported or directly refuted in the experimental literature. Despite this unfortunate precedent, aging is a very broad phenomenon that calls out for integration beyond the mere collecting together of results from disparate laboratory organisms. With this in mind, Part One offers several different synthetic perspectives. The editors, Rose and Finch, provide a verbal synthesis of the field that deliberately attempts to look at aging from both sides, the evolutionary and the molecular. The articles by Charlesworth and Clark both provide population genetic perspectives on aging, the former more mathematical, the latter more experimental. Bell takes a completely different approach, arguing that aging may not be the result of evolutionary forces. Bell's model instead proposes that aging could arise from the progressive deterioration of chronic host pathogen interactions. This is the first detailed publication of this model. It marks something of a return to the type of aging theories that predominated in the 1950's and 1960's, theories like the somatic mutation and error catastrophe theories. We hope that the reader will be interested by the contrast in views between the articles based on evolutionary theory and that of Bell. MR. Rose and C. E. Finch (eds. ), Genetics and Evolution of Aging, 5-12, 1994. © 1994 Kluwer Academic Publishers. The J aniform genetics of aging 2 Michael R. Rosel & Caleb E.
Aging Is A Group Selected Adaptation
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Author : Joshua Mitteldorf
language : en
Publisher: CRC Press
Release Date : 2017-02-03
Aging Is A Group Selected Adaptation written by Joshua Mitteldorf and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-03 with Medical categories.
Although books exist on the evolution of aging, this is the first book written from the perspective of again as an adaptive program. It offers an insight into the implications of research on aging genetics, The author proposes the Demographic Theory of Senescence, whereby aging has been affirmatively selected because it levels the death rate over time helping stabilize population dynamics and prevent extinctions.
The Evolution Of The Aging Self
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Author : Klaus Warner Schaie
language : en
Publisher: Springer Publishing Company
Release Date : 2000
The Evolution Of The Aging Self written by Klaus Warner Schaie and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
The authors examine age-related changes and their impact upon the concept of self - sense of well-being, life satisfaction, perceived quality of life. Each chapter is followed by two expert commentaries. For teachers, researchers and graduates interested in the sociology and psychology of ageing.
Methuselah Flies
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Author : Michael R Rose
language : en
Publisher: World Scientific
Release Date : 2004-06-14
Methuselah Flies written by Michael R Rose and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-14 with Science categories.
Methuselah Flies presents a trailblazing project on the biology of aging. It describes research on the first organisms to have their lifespan increased, and their aging slowed, by hereditary manipulation. These organisms are fruit flies from the species Drosophila melanogaster, the great workhorse of genetics. Michael Rose and his colleagues have been able to double the lifespan of these insects, and improved their health in numerous respects as well. The study of these flies with postponed aging is one of the best means we have of understanding, and ultimately achieving, the postponement of aging in humans. As such, the carefully presented detail of this book will be of value to research devoted to the understanding and control of aging. Methuselah Flies: • is a tightly edited distillation of twenty years of work by many scientists • contains the original publications regarding the longer-lived fruit flies • offers commentaries on each of the topics covered — new, short essays that put the individual research papers in a wider context • gives full access to the original data • captures the scientific significance of postponed aging for a wide academic audience Contents: Creation and Long-term Evolution of Methuselah FliesStress, Resistance, Physiology, and AgingReproduction, Nutrition, and AgingGenetics and Molecular Biology of Methuselah FliesReverse Evolution of Methuselah FliesAging, Development, and Crowding Readership: Biologists and doctors interested in the study of aging. Keywords:Aging;Evolution;Drosophila;Postponed Senescence;Fruit Flies
Does Aging Stop
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Author : Laurence D. Mueller
language : en
Publisher: OUP USA
Release Date : 2011-07-29
Does Aging Stop written by Laurence D. Mueller and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-29 with Health & Fitness categories.
Does Aging Stop? shatters the conventional beliefs on which aging research has been based for the last fifty years.
The Long Tomorrow
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Author : Michael R. Rose
language : en
Publisher: Oxford University Press
Release Date : 2005-09-15
The Long Tomorrow written by Michael R. Rose and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-15 with Science categories.
The conquest of aging is now within our grasp. It hasn't arrived yet, writes Michael R. Rose, but a scientific juggernaut has started rolling and is picking up speed. A long tomorrow is coming. In The Long Tomorrow, Rose offers us a delightfully written account of the modern science of aging, spiced with intriguing stories of his own career and leavened with the author's engaging sense of humor and rare ability to make contemporary research understandable to nonscientists. The book ranges from Rose's first experiments while a graduate student--counting a million fruit fly eggs, which took 3,000 hours over the course of a year--to some of his key scientific discoveries. We see how some of his earliest experiments helped demonstrate that "the force of natural selection" was key to understanding the aging process--a major breakthrough. Rose describes how he created the well-known Methuselah Flies, fruit flies that live far longer than average. Equally important, Rose surveys the entire field, offering colorful portraits of many leading scientists and shedding light on research findings from around the world. We learn that rodents given fifteen to forty percent fewer calories live about that much longer, and that volunteers in Biosphere II, who lived on reduced caloric intake for two years, all had improved vital signs. Perhaps most interesting, we discover that aging hits a plateau and stops. Popular accounts of Rose's work have appeared in The New Yorker, Time magazine, and Scientific American, but The Long Tomorrow is the first full account of this exciting new science written for the general reader. "Among his peers, Rose is considered a brilliantly innovative scientist, who has almost single-handedly brought the evolutionary theory of aging from an abstract notion to one of the most exciting topics in science."--Malcolm Gladwell, The New Yorker