Biomedical Frontiers Of Fluorine Chemistry
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Biomedical Frontiers Of Fluorine Chemistry
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Author :
language : en
Publisher:
Release Date : 1996
Biomedical Frontiers Of Fluorine Chemistry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
Biomedical Frontiers Of Fluorine Chemistry
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Author : Iwao Ojima
language : en
Publisher:
Release Date : 1996
Biomedical Frontiers Of Fluorine Chemistry written by Iwao Ojima and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
Developed from symposia sponsored by the Division of Fluorine Chemistry and the Division of Medicinal Chemistry.
Fluorine In Medicinal Chemistry And Chemical Biology
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Author : Iwao Ojima
language : en
Publisher: John Wiley & Sons
Release Date : 2009-03-23
Fluorine In Medicinal Chemistry And Chemical Biology written by Iwao Ojima and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-23 with Science categories.
The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: Discovery and development of fluorine containing drugs and drug candidates. New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. Structural and chemical biology of fluorinated amino acids and peptides. Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research.
Bioorganic And Medicinal Chemistry Of Fluorine
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Author : Jean-Pierre Bégué
language : en
Publisher: John Wiley & Sons
Release Date : 2008-06-02
Bioorganic And Medicinal Chemistry Of Fluorine written by Jean-Pierre Bégué and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-02 with Science categories.
Provides a thorough overview of the role of fluorine in pharmaceutical science and development Includes chapters on fluorinated analogues of natural products, fluorinated amino acids and peptides, and derivatives of sugars Classifies marketed and in-development fluorinated pharmaceuticals according to their therapeutic classes
Frontiers Of Organofluorine Chemistry
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Author : Iwao Ojima
language : en
Publisher: World Scientific
Release Date : 2019-12-24
Frontiers Of Organofluorine Chemistry written by Iwao Ojima and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-24 with Science categories.
This book focuses on the new frontiers of organofluorine chemistry in synthetic, organometallic, bioorganic, medicinal, agricultural, and materials chemistry as well as chemical physics and their applications to biomedical and material sciences. The extraordinary potential of fluorine-containing molecules in biology, pharmaceuticals, agrochemical, materials and their wide range of applications has been recognized by researchers who are not in the traditional fluorine chemistry field, and thus the new wave of organofluorine chemistry is rapidly expanding its frontiers.Featuring major leading researchers from all over the world and their cutting-edge research projects, this title reviews the recent advances and envision the new exciting developments in the future. Frontiers of Organofluorine Chemistry is an excellent reference book for professional researchers, and graduate students, in both industry and academia to get inspirations and new ideas for their projects.
Biomedical Chemistry
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Author : Paul F. Torrence
language : en
Publisher: John Wiley & Sons
Release Date : 2000-01-24
Biomedical Chemistry written by Paul F. Torrence and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-24 with Science categories.
How basic chemical ideas help advance the understanding and treatment of disease Biomedical Chemistry presents clear, concise coverage of the application of chemistry to drug discovery and determination of disease etiology, highlighting its role in the explosive growth of biotechnology and molecular biology. Through expert contributions from leading researchers in diverse fields, the book provides readers with an understanding of how fundamental chemical concepts are used in the development of novel approaches to the major problems in medicine today. The authors explain both the science and reasoning underlying each experimental approach, exploring cutting-edge developments in AIDS, cancer, alcoholism, Parkinson's disease, trypanosomiasis, emphysema, and malaria. Contemporary research problems discussed include: * Mechanism-based drug discovery * Design of new antitumor and antiviral agents * Targeting tumors using magnetic drug delivery * Antisense and antigene agents Easily accessible to anyone with a solid undergraduate background in chemistry, Biomedical Chemistry is an excellent resource for researchers in health-related fields as well as anyone seeking an overview of frontier topics in medicinal chemistry, organic chemistry, and biochemistry.
Fluorine Chemistry At The Millennium
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Author : R.E. Banks
language : en
Publisher: Elsevier
Release Date : 2000-12-04
Fluorine Chemistry At The Millennium written by R.E. Banks and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-04 with Science categories.
This volume brings together contributions by leading researchers covering a wide scope so characteristic of fluorine chemistry. It is a monograph of historical character comprising personalized accounts of progress and events in areas of particular interest.There is also much to interest and instruct chemists from other disciplines as a good proportion of the chapters contain a considerable amount of 'hard' referenced information relating to modern organic, organoelemental and inorganic chemistry. Historians of chemistry and technology will no doubt be tempted to dip into this book, and surely whoever addresses the task of commemorating Moissan's achievement at the 150-years stage will bless us all in some measure for its existence.
Organofluorine Compounds
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Author : Tamejiro Hiyama
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Organofluorine Compounds written by Tamejiro Hiyama and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
In view of increasing interest in organofluorine compounds, this book was undertaken to describe biological and physical properties of organofluorine compounds, synthetic methods of these, their roles in pharmaceutical, agrochemical and material sciences. In particular, the book will emphasize on the usefulness of fluorination reaction, availability of fluorination agents, so that even graduate students who are unfamiliar to this field can understand and participate in this fascinating heteroatom chemistry.
Experimental Methods In Organic Fluorine Chemistry
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Author : Tomoya Kitazume
language : en
Publisher: Routledge
Release Date : 2019-06-14
Experimental Methods In Organic Fluorine Chemistry written by Tomoya Kitazume and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-14 with Science categories.
In the fields of biologically active materials and functional materials, fluorinated organic materials are becoming a focus of significant interest. Over the past decade synthetic methodologies and reagents in fluorine chemistry have been developed, especially stereocontrolled synthetic methods, enzymatic resolution to synthesize enantiomers, fluoromethylated reagents, and fluorination reagents. These methods have contributed to the opening of new pathways for fluorinated materials. However, few fluorinated materials have been put to commercial use. Furthermore, there remain problems to be solved, such as the handling of the materials, availability of reagents and selectivity (stereo-, regio-, and/or chemoselectivity). Research chemists, technical engineers, and graduate students in all branches of chemistry, pharmaceutics, and material science interested in fluorinated materials need to know detailed experimental procedures of how to synthesize the target fluorinated materials. This volume summarizes the chemical and microbial methods for obtaining functionalized fluorinated materials for use as building blocks; detailed experimental methods (reaction conditions, solvent, temperature, handling techniques, etc.); and the stereoview (possible absolute configuration) of the structures with spectral data. Mono-, di-, tri-, and polyfluorinated materials derived from fluorinating agents, fluoromethylated reagents and building blocks are summarized. A chemical name index, molecular formula index, and reagent index are also included. The publication of this monograph will provide access to the enormous possibilities in fluorine chemistry, biological material chemistry, and functionalized material chemistry.
Organofluorines
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Author : A.H. Neilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-07-03
Organofluorines written by A.H. Neilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-07-03 with Medical categories.
This volume, written by a range of international experts, covers a wide range of topics involving organic fluorine compounds. Each chapter is preceded by a summary and includes extensive illustrations and references. The chapters cover atmospheric chemistry, application of 19F NMR, partition, degradation and transformation, naturally occurring organic fluorine compounds, toxicology of perfluoroalkanes and phosphorofluoridates, and application of aromatic compounds to the elucidation of the mechanism of cytochrome P450.