Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites


Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites
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Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites Volume 2


Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites Volume 2
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Author : Susanne Zeilinger
language : en
Publisher: Springer
Release Date : 2015-06-15

Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites Volume 2 written by Susanne Zeilinger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-15 with Science categories.


​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.



Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites


Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites
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Author : Juan-Francisco Martín
language : en
Publisher: Springer
Release Date : 2014-09-09

Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites written by Juan-Francisco Martín and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-09 with Science categories.


This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.



Laboratory Protocols In Fungal Biology


Laboratory Protocols In Fungal Biology
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Author : Vijai Kumar Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-09

Laboratory Protocols In Fungal Biology written by Vijai Kumar Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-09 with Science categories.


Laboratory Protocols in Fungal Biology presents the latest techniques in fungal biology. This book analyzes information derived through real experiments, and focuses on cutting edge techniques in the field. The book comprises 57 chapters contributed from internationally recognised scientists and researchers. Experts in the field have provided up-to-date protocols covering a range of frequently used methods in fungal biology. Almost all important methods available in the area of fungal biology viz. taxonomic keys in fungi; histopathological and microscopy techniques; proteomics methods; genomics methods; industrial applications and related techniques; and bioinformatics tools in fungi are covered and complied in one book. Chapters include introductions to their respective topics, list of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting. Each chapter is self-contained and written in a style that enables the reader to progress from elementary concepts to advanced research techniques. Laboratory Protocols in Fungal Biology is a valuable tool for both beginner research workers and experienced professionals. Coming Soon in the Fungal Biology series: Goyal, Manoharachary / Future Challenges in Crop Protection Against Fungal Pathogens Martín, García-Estrada, Zeilinger / Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites Zeilinger, Martín, García-Estrada / Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 van den Berg, Maruthachalam / Genetic Transformation Systems in Fungi Schmoll, Dattenbock / Gene Expression Systems in Fungi Dahms / Advanced Microscopy in Mycology



Fungal Secondary Metabolism


Fungal Secondary Metabolism
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Author : Nancy P. Keller
language : en
Publisher: Humana Press
Release Date : 2016-05-01

Fungal Secondary Metabolism written by Nancy P. Keller and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-01 with Medical categories.


This Methods in Molecular Biology volume provides key methodologies for accessing and exploiting natural product information provided by the genomes of filamentous fungi. Includes materials and reagents lists, step-by-step protocols and troubleshooting tips."



Applied Molecular Genetics Of Filamentous Fungi


Applied Molecular Genetics Of Filamentous Fungi
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Author : J.R. Kinghorn
language : en
Publisher: Springer Science & Business Media
Release Date : 1992-08-31

Applied Molecular Genetics Of Filamentous Fungi written by J.R. Kinghorn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-08-31 with Medical categories.


The filamentous fungi are perhaps unique in the diversity of their metabolic activities. This includes biosynthetic as well as degradative activities, many is to provide an of which are of industrial interest. The objective of this text up-to-date and broad review which emphasizes the genetic and molecular biological contribution in the field of fungal biotechnology. This text begins with an overview of the tools and methodologies involved which, to a large extent, have been developed in the model filamentous fungus Aspergillus nidulans and subsequently have been extended to commercially important fungi. This is followed by a chapter which provides a compilation of genes isolated from commercial fungi and their present status with respect to structure, function and regulation. Chapters 3 and 4 highlight the degradative powers of filamentous fungi. First, a discussion of what is known regarding the molecular genetics of fungi and the genes and enzymes involved in the beverage and food industries. This has an oriental flavour, reflecting the tremendous importance of fungi in traditional Chinese and Japanese food production. An account of lignocellulose degradation by filamentous fungi follows, illustrating the potential of fungi to utilize this substance as a renewable energy source. The ability of fungi to produce high-value foreign proteins is reviewed in chapters 5 and 6. Chymosin production, in particular, represents a good example of high-level yields being obtained, such as to warrant commercial production.



Secondary Metabolism And Differentiation In Fungi


Secondary Metabolism And Differentiation In Fungi
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Author : Bennett
language : en
Publisher: CRC Press
Release Date : 1983-07-21

Secondary Metabolism And Differentiation In Fungi written by Bennett and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-07-21 with Science categories.


The first source to unite secondary fungal metabolism and morphogenesis in one volume, Secondary Metabolism and Differentiation in Fungi treats biological systems as parts of a whole rather than as a series of individual elements, highlighting research in genetics, molecular biology, and ecology. Featuring the expertise of 19 international authorities, each chapter is a rich source of experimentation ideas. The book facilitates the application of novel techniques to existing problems in molecular mycology and explores potentials for major new research. This indispensable guide to a key scientific field benefits biologists, chemists, and other scientists.



Chemical Fungal Taxonomy


Chemical Fungal Taxonomy
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Author : Jens C. Frisvad
language : en
Publisher: CRC Press
Release Date : 2020-10-14

Chemical Fungal Taxonomy written by Jens C. Frisvad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-14 with Science categories.


Offers comprehensive coverage of the latest developments in both biochemical and physiological approaches to fungal systematics. Incorporates recent advances in molecular biology into systematics methods that can revolutionize taxonomic schemes.



Fungal Jewels Secondary Metabolites


Fungal Jewels Secondary Metabolites
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Author : Nancy Keller
language : en
Publisher: Frontiers Media SA
Release Date : 2017-04-10

Fungal Jewels Secondary Metabolites written by Nancy Keller and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-10 with Electronic book categories.


Fungal natural products are friends and foes of humans such as deleterious mycotoxins, cytotoxic, carcinogenic compounds or beneficial compounds such as antibiotics, fungicides, insecticides, antiviral and antitumor metabolites. Understanding fungal diversity and estimation of fungal species on our planet poses a great challenge to researchers. This complexity is further multiplied by secondary metabolite diversity of fungi, which requires interdisciplinary studies. It is extremely important to understand the fungal secondary metabolism to stop human, animal and plant diseases caused by fungi and harvest their valuable metabolites. Furthermore, many secondary metabolite gene clusters are silenced under laboratory conditions. It is vital to develop effective methods to activate those clusters in order to discover novel potent metabolites. This e-book is a compilation of original review articles contributed by leading fungal secondary metabolite researchers with a wide range of expertise. Important aspects of fungal secondary metabolism, including regulation, genome mining, evolution, synthetic biology and novel methods have been discussed. This book will be a great source to those people, who are interested in understanding overall structure, diversity and regulation of production of these tiny but precious chemicals.



Physiology And Genetics


Physiology And Genetics
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Author : Timm Anke
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-18

Physiology And Genetics written by Timm Anke and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Science categories.


In the last decade the discipline of mycology has been substantially changed by new research technologies. In particular DNA-based tools for the investigation of fungal taxonomy, signal transduction and regulation, and biosynthetic potential have accelerated advances in mycological knowledge. This volume presents a selection of exciting issues on basic and applied aspects of fungal physiology and genetics. In 18 chapters renowned experts provide an overview of traditional as well as current and future aspects of potential application of fungi in biotechnology. The contributions can be used by scientists to keep up-to-date on the latest developments in the corresponding research area, and by students to familiarize themselves with the different topics.



Advances In Fungal Biotechnology For Industry Agriculture And Medicine


Advances In Fungal Biotechnology For Industry Agriculture And Medicine
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Author : Jan S. Tkacz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Advances In Fungal Biotechnology For Industry Agriculture And Medicine written by Jan S. Tkacz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


In the past half century, filamentous fungi have grown in commercial importance not only in the food industry but also as sources of pharmaceutical agents for the treatment of infectious and metabolic diseases and of specialty proteins and enzymes used to process foods, fortify detergents, and perform biotransformations. The commercial impact of molds is also measured on a negative scale since some of these organisms are significant as pathogens of crop plants, agents of food spoilage, and sources of toxic and carcinogenic compounds. Recent advances in the molecular genetics of filamentous fungi are finding increased application in the pharmaceutical, agricultural, and enzyme industries, and this trend promises to continue as the genomics of fungi is explored and new techniques to speed genetic manipulation become available. This volume focuses on the filamentous fungi and highlights the advances of the past decade, both in methodology and in the understanding of genomic organization and regulation of gene and pathway expression.