Cell Cycle Regulation And Differentiation In Cardiovascular And Neural Systems
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Cell Cycle Regulation And Differentiation In Cardiovascular And Neural Systems
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Author : Antonio Giordano
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-08-17
Cell Cycle Regulation And Differentiation In Cardiovascular And Neural Systems written by Antonio Giordano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-17 with Medical categories.
Complex physiopathological relationships have been proven to exist between two of the body’s most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another. The text looks at several aspects of the cardiovascular and nervous systems from a new point of view, describing the differences and similarities in their differentiation pathways with an emphasis on the role of cell cycle regulation and cell differentiation. Topics discussed include neurogenesis in the central nervous system, neural stem cells, and the basic-helix-loop-helix transcription factors in neural differentiation. Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.
The Developing Human 11th Edition South Asia Edition E Book
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Author : Keith L Moore
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-06-24
The Developing Human 11th Edition South Asia Edition E Book written by Keith L Moore and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-24 with Medical categories.
Extensively revised to incorporate recent research and current clinical practice, The Developing Human: Clinically Oriented Embryology, South Asia Edition, covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textbook is designed to successfully meet the needs of medical and health sciences profession students, as well as those in graduate programs. It provides an easy-to-digest, comprehensive review of what can be a complex and challenging subject.• Guides readers month by month and stage by stage through embryo and fetal organ and systems development, using full-color photographs of clinical cases, relevant modern medical imaging, and numerous high-quality supportive figures.• Includes many new 3D HD color rendered images of embryos and fetuses, as well as 3D reconstructions of whole embryos.• Provides clinically-oriented problems for each chapter, with corresponding answers and explanations designed to facilitate discussion and learning. In addition, multiple-choice questions and answers are available online for supportive self-assessment.• Features 18 exceptional color animations, now with narration, to help students as they explore and learn the complexity of embryological development.• Provides the knowledge base needed for today's examinations, including USMLE Step 1, as well as for future clinical practice.• Thoroughly updated information includes new annotations on fundamental molecular events during embryogenesis, now required for many professional examinations.• Includes enhanced clinical material in all chapters, with updated tables, Clinical Case highlights and a critical chapter on common signalling pathways during development that covers gene editing (CRISPR/Cas9), induced pluripotent stem cells (iPS), a revision of the sonic hedgehog signalling pathway; and more.• Details how molecular biology has affected clinical practice, including techniques such as recumbent DNA technology and stem cell manipulation.
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1987
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medicine categories.
Yy1 In The Control Of The Pathogenesis And Drug Resistance Of Cancer
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Author : Benjamin Bonavida
language : en
Publisher: Academic Press
Release Date : 2020-10-20
Yy1 In The Control Of The Pathogenesis And Drug Resistance Of Cancer written by Benjamin Bonavida and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-20 with Science categories.
YY1 Is Pivotal in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes the current state-of-the-art of the transcription factor YY1 that is overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. This book emphasizes the biochemical, molecular and genetic underlying mechanisms by which YY1 regulates its pro-cancerous activities. In addition, it also describes the role of YY1 in the regulation of tumor cell resistance to conventional chemo and immunotherapies and the important role of inhibiting YY1 in cancer. This book is a valuable source for cancer researchers, oncologists and several members of medical and biomedical field who are interested in understanding further the role of YY1 in cancer. - Provides a thorough understanding of the underlying mechanisms by which YY1 regulates cancer cell phenotype and unique characteristics - Discusses the novel mechanisms of YY1 regulation of tumor cell resistance and means to overcome resistance - Encompasses new examples of newly developed non-toxic and selective inhibitors targeting YY1
The Developing Human E Book
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Author : Keith L. Moore
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-12-19
The Developing Human E Book written by Keith L. Moore and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-19 with Medical categories.
The Developing Human: Clinically Oriented Embryology, by Drs. Keith L. Moore, T.V.N. Persaud, and Mark G. Torchia, delivers the world’s most complete, visually rich, and clinically oriented coverage of this complex subject. Written by some of the world’s most famous anatomists, it presents week-by-week and stage-by-stage views of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes play in development. Acquire a detailed grasp of human embryology with the world’s most comprehensive, richly illustrated, and clinically oriented coverage from a cadre of leading world authorities. Effectively prepare for exams with review questions and answers at the end of each chapter. Understand all of the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development. See how discoveries in molecular biology have affected clinical practice, including the development of sophisticated new techniques such as recumbent DNA technology and stem cell manipulation. Prepare for the USMLE Step 1 with clinical case presentations, highlighted in special boxes, that demonstrate how embryology concepts relate to clinical practice.
Principles Of Developmental Genetics
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Author : Sally A. Moody
language : en
Publisher: Academic Press
Release Date : 2014-09-02
Principles Of Developmental Genetics written by Sally A. Moody and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-02 with Science categories.
Providing expert coverage of all major events in early embryogenesis and the organogenesis of specific systems, and supplemented with representative clinical syndromes, Principles of Developmental Genetics, Second Edition discusses the processes of normal development in embryonic and prenatal animals, including humans. The new edition of this classic work supports clinical researchers developing future therapies with its all-new coverage of systems biology, stem cell biology, new technologies, and clinical disorders. A crystal-clear layout, exceptional full-color design, and bulleted summaries of major takeaways and clinical pathways assist comprehension and readability of the highly complex content. - All-new coverage of systems biology and stem cell biology in context of evolving technologies places the work squarely on the modern sciences - Chapters are complemented with a bulleted summary for easy digestion of the major points, with a clinical summary for therapeutic application - Clinical highlights provides a bridge between basic developmental biology and clinical sciences in embryonic and prenatal syndromes
Stem Cell Regulators
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Author : Gerald Litwack
language : en
Publisher: Academic Press
Release Date : 2011-12-12
Stem Cell Regulators written by Gerald Litwack and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-12 with Medical categories.
Factors operating in pluripotent cells -- Molecular mediators of Mesenchymal Stem Cell (MSC) -- Insulin and germline proliferation in Caenorhabditis -- Generation of mature ß-cells from embryonic stem cells: What are we missing? -- Activation and regulation of reserve liver progenitor cells -- Adult cardiac-derived stem cells: differentiation and survival regulators -- TGF-Beta1 regulates differentiation of bone marrow mesenchymal stem cells -- Maternal intake of folic acid and neural crest stem cells -- Modulation of the generation of dopaminergic neurons from human neural stem cells by Bcl-XL. Mechanisms of action -- Glucocorticoid hedgehog agonists in neurogenesis -- Effect of progesterone on human mesenchymal stem cells -- Regulation of muscle stem cell activation -- the role of growth factors and extracellular matrix -- Thymosins and muscle regeneration -- Micro RNAs and mesenchymal stem cells -- MicroRNA and vascular smooth muscle cells -- Transforming growth factor beta superfamily in mouse embryonic stem cell self-renewal -- The biology of HIFa proteins in cell differentiation and disease -- Regulatory role of Klf5 in early mouse development and in embryonic stem cells -- Bam and Bgcn in Drosophila germ line stem cell differentiation -- The effects of mechanical loading on mesenchymal stem cell differentiation and matrix production.
Biomedical Index To Phs Supported Research
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Author :
language : en
Publisher:
Release Date : 1987
Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medicine categories.
Signaling In The Heart
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Author : José Marín-García
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-21
Signaling In The Heart written by José Marín-García and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-21 with Medical categories.
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Post Genomic Cardiology
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Author : José Marín-García
language : en
Publisher: Academic Press
Release Date : 2014-05-09
Post Genomic Cardiology written by José Marín-García and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-09 with Medical categories.
In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the "epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. - Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches - Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome - Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs