Innovative 3d Models For Understanding Mechanisms Underlying Lung Diseases Powerful Tools For Translational Research
DOWNLOAD
Download Innovative 3d Models For Understanding Mechanisms Underlying Lung Diseases Powerful Tools For Translational Research PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Innovative 3d Models For Understanding Mechanisms Underlying Lung Diseases Powerful Tools For Translational Research book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Innovative 3d Models For Understanding Mechanisms Underlying Lung Diseases Powerful Tools For Translational Research
DOWNLOAD
Author : Janette K. Burgess
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-05
Innovative 3d Models For Understanding Mechanisms Underlying Lung Diseases Powerful Tools For Translational Research written by Janette K. Burgess and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-05 with Science categories.
The mechanisms underlying acute and chronic lung diseases are complex, reflecting the interplay between multiple cell types, their microenvironment and exogenous challenges. While traditional in vitro cell culture approaches have been instrumental in advancing our knowledge of cellular signalling and function, they typically lack the cell-cell and cell-matrix interactions that define the niche in which lung cell and tissue functions emerge. Implementing in vivo and ex vivo three-dimensional (3D) models more realistically mimicking the in vivo cell-extracellular matrix (ECM) crosstalk should facilitate a considerable leap towards better understanding lung diseases and thus in investigating new pharmacological tools. We are experiencing a revolution in our understanding of the cell types that deposit and remodel ECM in the lung, the dynamic spatial composition of the ECM and cell-cell interactions during disease, and the influence of ECM and cell-derived cues on lung cell biology. In concert, the ex vivo and in vitro models that are being used to examine the role of the 3D microenvironment of the cell in the lung are rapidly developing. The European Respiratory Society has partnered with Frontiers in Pharmacology to launch this research topic in conjunction with the ERS Research Seminar “Innovative 3D models for understanding mechanisms underlying lung diseases: powerful tools for translational research”.
Engineering Translational Models Of Lung Homeostasis And Disease
DOWNLOAD
Author : Chelsea M. Magin
language : en
Publisher: Springer Nature
Release Date : 2023-05-17
Engineering Translational Models Of Lung Homeostasis And Disease written by Chelsea M. Magin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-17 with Science categories.
Cutting-edge engineering approaches towards modelling lung homeostasis and disease have created dynamic new opportunities for interdisciplinary collaboration and unprecedented progress toward understanding and treating lung disease. This text connects established research in lung biology and physiology to innovative engineering strategies for pulmonary modelling. This unique approach aims to encourage and facilitate progress among a greater audience of basic and translational scientists, clinicians, and medical practitioners. Engineering Translational Models of Lung Homeostasis and Disease illustrates the advances in lung tissue characterization, revealing dynamic changes in the structure, mechanics, and composition of the extracellular matrix. This information paves the way for tissue-informed engineering models of pulmonary tissue, improved design of clinical materials, and advances against a variety of common pathologies. Current translational challenges are highlighted, as are engineering opportunities to overcome these barriers. This foundational text holds valuable lessons for researchers and clinicians throughout the fields of engineering, materials science, cell biology, pulmonary medicine, and clinical science. · Each section focuses on a specific region of the lung, presenting either the biological or clinical perspective along with complimentary engineering approaches · Covers the interface of engineering and lung biology · Highlights emerging new models to study lung disease and repair Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
Mechanisms Of Molecular Carcinogenesis Volume 2
DOWNLOAD
Author : Johannes Haybaeck
language : en
Publisher: Springer
Release Date : 2017-05-22
Mechanisms Of Molecular Carcinogenesis Volume 2 written by Johannes Haybaeck and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-22 with Medical categories.
Together with Volume 1, this book provides an inclusive overview of the molecular and cellular mechanisms of carcinogenesis and offers comprehensive insights into related clinical and therapeutic aspects. This second volume complements the first by presenting and concisely explaining the carcinogenesis of various tumor entities such as non-melanoma skin cancers, bone and soft tissue tumors, pancreatic cancers, hepatocellular cancer and neuroendocrine tumors. As in volume one, each chapter illuminates the similarities and dissimilarities of changed signaling pathways in the different organ systems and depicts potential therapeutic strategies. The focus of volume two lies on the presentation of modern molecular biological techniques for diagnosis, as well as strategies for biomarker identification and validation. Furthermore, it discusses potential therapeutic targets and individualized treatment strategies, offering a valuable resource for all basic scientists and medical researchers interested in translational cancer research.
Bioengineering Systems For Therapeutic And In Vitro Platforms
DOWNLOAD
Author : Loredana De Bartolo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-22
Bioengineering Systems For Therapeutic And In Vitro Platforms written by Loredana De Bartolo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-22 with Science categories.
Cell Interaction Molecular And Immunological Basis For Disease Management
DOWNLOAD
Author : Bhawana Singh
language : en
Publisher:
Release Date : 2021
Cell Interaction Molecular And Immunological Basis For Disease Management written by Bhawana Singh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
From Single Stem Cells To Organoids Organ Repair And Public Health
DOWNLOAD
Author : Lon J. Van Winkle
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-09
From Single Stem Cells To Organoids Organ Repair And Public Health written by Lon J. Van Winkle and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-09 with Science categories.
The Impact Of Food Bioactives On Health
DOWNLOAD
Author : Kitty Verhoeckx
language : en
Publisher: Springer
Release Date : 2015-04-29
The Impact Of Food Bioactives On Health written by Kitty Verhoeckx and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-29 with Technology & Engineering categories.
“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.
Mri Of The Lung
DOWNLOAD
Author : Hans-Ulrich Kauczor
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-10-28
Mri Of The Lung written by Hans-Ulrich Kauczor and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-28 with Medical categories.
During the past decade significant developments have been achieved in the field of magnetic resonance imaging (MRI), enabling MRI to enter the clinical arena of chest imaging. Standard protocols can now be implemented on up-to-date scanners, allowing MRI to be used as a first-line imaging modality for various lung diseases, including cystic fibrosis, pulmonary hypertension and even lung cancer. The diagnostic benefits stem from the ability of MRI to visualize changes in lung structure while simultaneously imaging different aspects of lung function, such as perfusion, respiratory motion, ventilation and gas exchange. On this basis, novel quantitative surrogates for lung function can be obtained. This book provides a comprehensive overview of how to use MRI for imaging of lung disease. Special emphasis is placed on benign diseases requiring regular monitoring, given that it is patients with these diseases who derive the greatest benefit from the avoidance of ionizing radiation.
Principles Of Regenerative Medicine
DOWNLOAD
Author : Anthony Atala
language : en
Publisher: Academic Press
Release Date : 2010-12-16
Principles Of Regenerative Medicine written by Anthony Atala and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-16 with Science categories.
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs
The Chemical Components Of Tobacco And Tobacco Smoke
DOWNLOAD
Author : Alan Rodgman
language : en
Publisher: CRC Press
Release Date : 2016-04-19
The Chemical Components Of Tobacco And Tobacco Smoke written by Alan Rodgman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Authored by two longtime researchers in tobacco science, The Chemical Components of Tobacco and Tobacco Smoke, Second Edition chronicles the progress made from late 2008 through 2011 by scientists in the field of tobacco science. The book examines the isolation and characterization of each component. It explores developments in pertinent analytical