Junk Dna
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Junk Dna
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Author : Nessa Carey
language : en
Publisher: Icon Books
Release Date : 2015-03-05
Junk Dna written by Nessa Carey and has been published by Icon Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-05 with Science categories.
From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.
What S In Your Genome
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Author : Laurence A. Moran
language : en
Publisher: University of Toronto Press
Release Date : 2023-05-16
What S In Your Genome written by Laurence A. Moran and has been published by University of Toronto Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-16 with Science categories.
What’s in Your Genome? describes the functional regions of the human genome, the evidence that 90% of it is junk DNA, and the reasons this evidence has not been widely accepted by the popular press and much of the scientific community. The human genome contains about 25,000 protein-coding and noncoding genes and many other functional elements, such as origins of replication, regulatory elements, and centromeres. Functional elements occupy only about 10 percent of the more than three billion base pairs in the human genome. Much of the rest is composed of ancient fragments of broken genes, transposons, and viruses. Almost all of this is thought to be junk DNA, based on evidence that dates back fifty years. This conclusion is controversial. What’s in Your Genome? describes the arguments on both sides of the debate and attempts to explain the reasoning behind those different points of view. The book corrects a number of false narratives that have arisen in recent years and examines how they have affected the debate over junk DNA. In addition, Laurence A. Moran focuses on scientific misconceptions and misinformation and on how the junk DNA controversy has been incorrectly portrayed in both the scientific literature and the popular press. Tracing the earliest indications of junk DNA back to the 1960s, the book explains the success of nearly neutral theory and the importance of random genetic drift, which gave rise to the view that evolution produces sloppy genomes full of junk DNA. What’s in Your Genome? aims to offer the most accurate and current account of the human genome.
The Myth Of Junk Dna
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Author : Jonathan Wells
language : en
Publisher: Discovery Inst
Release Date : 2011
The Myth Of Junk Dna written by Jonathan Wells and has been published by Discovery Inst this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
According to the modern version of Darwin's theory, DNA contains a program for embryo development that is passed down from generation to generation; the program is implemented by proteins encoded by the DNA, and accidental DNA mutations introduce changes in those proteins that natural selection then shapes into new species, organs and body plans. When scientists discovered forty years ago that about 98% of our DNA does not encode proteins, the non-protein-coding portion was labeled “junk” and attributed to molecular accidents that have accumulated in the course of evolution. Recent books by Richard Dawkins, Francis Collins and others have used this “junk DNA” as evidence for Darwinian evolution and evidence against intelligent design (since an intelligent designer would presumably not have filled our genome with so much garbage). But recent genome evidence shows that much of our non-protein-coding DNA performs essential biological functions. The Myth of Junk DNA is written for a general audience by biologist Jonathan Wells, author of Icons of Evolution. Citing some of the abundant evidence from recent genome projects, the book shows that “junk DNA” is not science, but myth.
Genomic Elements In Health Disease And Evolution
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Author : Kyriacos Felekkis
language : en
Publisher: Springer
Release Date : 2016-08-23
Genomic Elements In Health Disease And Evolution written by Kyriacos Felekkis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.
Over 98% of the human genome contains non-coding DNA sequences. For many years molecular biologists referred to this component of the genome as the “junk” DNA since it does not code for any “useful” protein product. Over the last years this notion changed significantly as scientists discovered that a large part of this DNA contains various genomic elements that have important roles in cell physiology. Genomic elements such as non-coding RNAs, transposons, splicing RNAs, DNA repeats and others were shown to play a significant role in regulating gene expression. In addition, all these elements were implicated to contribute in the pathogenesis or progression of various human diseases. In this book, the editor will attempt to describe all these genomic elements that constitute the junk DNA of the genome. For every genomic element, the physiologic role in the organism, its role in evolution and any possible involvement in human diseases will be discussed. Additionally, interaction between these elements in normal or pathologic condition will be discussed. Since a large amount of new knowledge is generated daily in regards to these genomic elements, this book will attempt to combine all the information in a single publication that can serve as a reference for future studies. The first part will discuss RNA elements such as microRNAs, long non-coding RNAs, piRNAs and splicing RNAs. The second part of the book will deal with transposons, retrotransposons and DNA transposons. Finally the third part of the book will discuss DNA elements that include DNA repeats, conserved non-coding sequences, distal genomic elements, introns, pseudogenes, CpG islands and telomeres. For miRNAs and CNVs a separate chapter will be dedicated to their role in human diseases since an extensive amount of information exists about these two elements.
Genomic Elements In Health Disease And Evolution
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Author : Kyriacos Felekkis
language : en
Publisher:
Release Date : 2015
Genomic Elements In Health Disease And Evolution written by Kyriacos Felekkis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
This book provides a thorough review of various non-coding genomic elements and discusses in depth their role in health, disease and evolution. It begins with an exploration of non-coding RNA molecules miRNAs, piRNAs, LncRNAs and transposable elements as these moieties dominate the scientific literature the last ten years. The second part of the book discusses copy number variation regions, mini and micro satellites, and proximal and distal elements of the genome. The last section of the book focuses on the review of well-known non-coding regions of the genome, introns, centromeres and telomeres, but enriched with newly discovered functions. As the vast amount of data in regards to these elements is attributed to a great degree to the growing technology in the field of biomedicine, the last chapter of the book discusses the latest development in the field of Next Generation Sequence and the potential applications of this technology in the study of non-coding regions of the genome. This new volume provides an in depth background on 'junk DNA' and helps set the stage for future research, and is an essential tool for those in the field.
From Junk Dna To Clinically Relevant Tools For Cancer Diagnosis Staging And Tailored Therapies The Incredible Case Of Non Coding Rnas
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Author : Marilena V. Iorio
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-22
From Junk Dna To Clinically Relevant Tools For Cancer Diagnosis Staging And Tailored Therapies The Incredible Case Of Non Coding Rnas written by Marilena V. Iorio and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-22 with categories.
Junk Dna
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Author : Joseph Scogna
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2014-09-27
Junk Dna written by Joseph Scogna and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-27 with categories.
98% of our DNA is considered by mainstream science to be "genetic gibberish, junk."This very title pokes fun at that notion because deep inside, we know the truth! Open the pages of this book and unlock the hidden secrets.....Our DNA contains everything we needed to know to survive for the past millennia. 5 senses? How about 128 Sensory Channels: perceptions that helped Stone Age mankind survive and could enhance our world today. Auras, electromagnetic fields, radiational and gravitational forces, bio-energetics, sounds, colors, energy centers, endocrine senses, Sun, magnetic reference for people and places, mathematics, God, language, spirits, solar system, and many more. All the healing knowledge we humans need to know about has been embedded and stored in the crystals of our own DNA. Crystals transmit information to us, about survival, about our past and about healing. We have 'forgotten' much - we just need to access, to listen, and be open to the possibilities. So take a step back in time and discover what has been stored in the genes since the earliest moments of creation. Your journey to self awareness starts here. "The double helix presented as never before! Scogna teaches us about life at the crystal level as no research scientist would think to describe it." -Mary Habeeb "The Macro-Micro aspects of the cosmos and humankind. Just like Tesla, some spirits arrive well before their time. Joe Scogna pulled back the veil of time to show us a new understanding of ourselves and instill the courage to embrace what is needed and to heal in these challenging times." -Bruce L. Erickson, Mother Earth Media "Learn about the 128 sense perceptions-not just five!-and how we are each imbued with crystalline structures in our RNA/DNA which are constantly evolving and changing to insure survival, towards our betterment and optimal health. Scogna purported this long before anyone had a clue." -Nancy B. Porter, DN, LISW "Joe Scogna's explanation of how life forms are altered by a natural process supports an evolutionist's position, but the concept of a genetic planning mechanism suggests an intelligent designer at work. Who designed that mechanism?" -Linda Schwank
Junk Dna
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Author : Tania Glyde
language : en
Publisher:
Release Date : 2000-08-16
Junk Dna written by Tania Glyde and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-16 with Genetic engineering categories.
When sex therapist Regina incorporates stolen pharmaceuticals into her unconventional work, the women she treats develop a terrifying aversion to children. Not one of her best ideas. Disillusioned, she embarks on a work of scientific satire, a living exhibition of genetic poetry starting with mice and working up the evolutionary scale. In the flat upstairs, ten year old Lucy, a dyslexic, creative genius, was born into a family on the wrong side of dysfunctional. As society starts to fall apart, Lucy quits school, orphans herself, and sets to work as Regina's assistant. Lucy is now a very powerful little girl, and life is getting more twisted by the day. Finally, somebody 'up there' has had enough of human beings tinkering with nature, and Junk DNA reaches its apocalyptic climax.
Junk Dna
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Author : Sean Brandywine
language : en
Publisher:
Release Date : 2014-09-18
Junk Dna written by Sean Brandywine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-18 with categories.
The Epigenetics Revolution
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Author : Nessa Carey
language : en
Publisher: Columbia University Press
Release Date : 2012-03-06
The Epigenetics Revolution written by Nessa Carey and has been published by Columbia University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-06 with Science categories.
Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.