Kanker Tinjauan Molekuler Dan Kandidat Senyawa Antikanker
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Kanker Tinjauan Molekuler Dan Kandidat Senyawa Antikanker
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Author : Prof. Dr. apt. Muhammad Da’i, M.Si.
language : id
Publisher: Muhammadiyah University Press
Release Date :
Kanker Tinjauan Molekuler Dan Kandidat Senyawa Antikanker written by Prof. Dr. apt. Muhammad Da’i, M.Si. and has been published by Muhammadiyah University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
Penyakit kanker masih menjadi problem besar di Indonesia dan di dunia. Hal ini minimal disebabkan dua hal yaitu: 1). Insidensi yang semakin meningkat setiap tahun dan 2). Belum ada pengobatan radikal yang bisa mematikan sel kanker tanpa efek samping. Buku ini bisa menjadi referensi bagi mahasiswa maupun peneliti untuk mengeksplorasi senyawa-senyawa yang berpotensi sebagai anti kanker. Kajian molekuler mendasari mekenisme kerja senyawa tersebut, sehingga diharapkan dimasa depan didapatkan senyawa/isolate anti kanker dari tanaman obat yang minimal efek samping.
Drugs From The Sea
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Author : Nobuhiro Fusetani
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2000-01-01
Drugs From The Sea written by Nobuhiro Fusetani and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-01 with Medical categories.
The present book consists of three parts: discovery, development and production of drugs from marine organisms. Marine bacteria, fungi, microalgae, sponges and opisthobranch mollusks have attracted much attention as sources of potential drugs, which is described in the first part. A pain-killing drug developed from the venom of a cone shell is a recent highlight of marine natural product research; the interesting story of its discovery is provided. The second part features an anticancer drug with a novel mode of action which was originally isolated from a songe and a potential antiosteoporotic drug of a hexacoral origin. But the most serious problem for development of drugs from the sea remains supply. Two possible solutions, production by fermentation and by aquaculture, are described in the third part. Identification and culture of symbiotic bacteria which are responsible for the production of bioactive sponge metabolites are the main objectives for many researchers.
Culturing Nerve Cells
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Author : Gary Banker
language : en
Publisher: MIT Press
Release Date : 1998
Culturing Nerve Cells written by Gary Banker and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Anatomy categories.
A do-it-yourself manual for culturing nerve cells, complete with recipes and protocols.
Molecular Design
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Author : Gisbert Schneider
language : en
Publisher: John Wiley & Sons
Release Date : 2008-02-26
Molecular Design written by Gisbert Schneider and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-26 with Science categories.
Kleine Moleküle für Einsteiger: Dieser für Lehre und Selbststudium gleichermaßen geeignete Band behandelt den computergestützten Entwurf von Wirkstoffen, Enzyminhibitoren, Sonden und Markern für Biomoleküle und führt den Leser bis zum ersten eigenen De-Novo-Design eines funktionellen Moleküls. Gestützt auf lange Erfahrung im Molecular-Modeling-Umfeld erläutern die Autoren, welche Fragen mit den beschriebenen Methoden beantwortet werden können (und welche nicht).
Virtual Screening In Drug Discovery
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Author : Juan Alvarez
language : en
Publisher: CRC Press
Release Date : 2005-03-24
Virtual Screening In Drug Discovery written by Juan Alvarez and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-24 with Medical categories.
Virtual screening can reduce costs and increase hit rates for lead discovery by eliminating the need for robotics, reagent acquisition or production, and compound storage facilities. The increased robustness of computational algorithms and scoring functions, the availability of affordable computational power, and the potential for timely structural determination of target molecules, have provided new opportunities for virtual screening, and made it more practical. Why then, isn’t everyone using virtual screening? Examining the scope and limitations of this method, Virtual Screening in Drug Discovery explores the algorithms involved and how to actually use them. Part I offers perspectives on both ligand-based and docking-based virtual screens. The authors of these chapters frame many of the challenges currently facing the field. Part II considers the choice of compounds that are best suited as drug leads. Part III discusses ligand-based approaches, including descriptor-based similarity, traditional pharmacophore searching, and similarity based 3D-pharmacophore fingerprints. The final two sections are devoted to molecular docking. Part IV outlines some important and practical considerations relating to the energetics of protein-ligand binding and target-site topography, whereas specific docking algorithms and strategies are discussed in Part V. Notwithstanding this list of subjects, the book does not overwhelm you with more information than you need—many of the strategies outlined will transcend the specifics of any given method. Nor does the book purport to offer single best ways to use the programs. What it does is provide a snapshot of virtual screening that gives you easy access to strategies and techniques for lead discovery. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.
Antioxidants In Food
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Author : Jan Pokorny
language : en
Publisher: CRC Press
Release Date : 2001-04-12
Antioxidants In Food written by Jan Pokorny and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-04-12 with Technology & Engineering categories.
Antioxidants are an increasingly important ingredient in food processing. Their traditional role is, as their name suggests, in inhibiting the development of oxidative rancidity in fat-based foods, particularly meat and dairy products and fried foods. However, more recent research has suggested a new role in inhibiting cardiovascular disease and cancer. Antioxidants in Food: Practical Applications provides a review of the functional role of antioxidants and discusses how they can be effectively exploited by the food industry. The first part of the book looks at antioxidants and food stability with chapters on the development of oxidative rancidity in foods, methods for inhibiting oxidation, and ways of measuring antioxidant activity. Part 2 looks at antioxidants and health, including chapters on antioxidants and cardiovascular disease, their antitumour properties, and bioavailability. A major trend in the food industry, driven by consumer concerns, has been the shift from the use of synthetic to natural ingredients in food products. Part 3 looks at the range of natural antioxidants available to the food manufacturer. The final section of the book looks at how these natural antioxidants can be effectively exploited, covering such issues as regulation, preparation, antixoxidant processing functionality and their use in a range of food products from meat and dairy products, frying oils and fried products, to fruit and vegetables and cereal products.
Mass Spectrometry In Medicinal Chemistry
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Author : Klaus Wanner
language : en
Publisher: John Wiley & Sons
Release Date : 2007-06-27
Mass Spectrometry In Medicinal Chemistry written by Klaus Wanner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-27 with Science categories.
This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory. Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands -- all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding.
Computer Assisted Drug Design
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Author : Edward C. Olson
language : en
Publisher:
Release Date : 1979
Computer Assisted Drug Design written by Edward C. Olson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.
Bioinformatics For Dummies
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Author : Jean-Michel Claverie
language : en
Publisher: John Wiley & Sons
Release Date : 2011-02-10
Bioinformatics For Dummies written by Jean-Michel Claverie and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-10 with Science categories.
Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop! Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You’ll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to: Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what’s going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you'll be searching databases and analyzing sequences like a pro!
Human Papilloma Viruses
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Author : D.J. McCance
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-09-13
Human Papilloma Viruses written by D.J. McCance and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-13 with Medical categories.
This book describes up-to-date information on the pathogenesis and molecular biology of human papillomaviruses and describes the mechanistic role of the viruses in epithelial cancers. Included in the book are chapters on the epidemiology of human papillomaviruses, the factors that control replication and transcription and the viral proteins, which are involved in modulating the biology of the host cell leading to cancer. Details of the immune response to the viruses and potential vaccine strategies are discussed.