Pharmacokinetics And Pharmacodynamics Of Nanoparticulate Drug Delivery Systems
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Pharmacokinetics And Pharmacodynamics Of Nanoparticulate Drug Delivery Systems
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Author : Jayvadan K. Patel
language : en
Publisher: Springer Nature
Release Date : 2022-03-07
Pharmacokinetics And Pharmacodynamics Of Nanoparticulate Drug Delivery Systems written by Jayvadan K. Patel and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-07 with Science categories.
A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.
Nanoparticulate Drug Delivery Systems
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Author : Yoon Yeo
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-25
Nanoparticulate Drug Delivery Systems written by Yoon Yeo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-25 with Science categories.
Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.
Pharmacokinetics And Pharmacodynamics Of Novel Drug Delivery Systems From Basic Concepts To Applications
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Author : Sankalp A Gharat
language : en
Publisher: Springer
Release Date : 2024-03-03
Pharmacokinetics And Pharmacodynamics Of Novel Drug Delivery Systems From Basic Concepts To Applications written by Sankalp A Gharat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-03 with Medical categories.
The book delves into the intricate realm of pharmacokinetics and pharmacodynamics as they apply to modern advancements in drug delivery systems. It offers a comprehensive exploration of novel drug delivery methods, with a particular focus on nanoparticles and nanocarriers. The absorption, distribution, metabolism, and excretion processes of nanoparticles are extensively examined. It also covers various evaluation models, spanning from preclinical to clinical, aimed at assessing the effectiveness and safety of nanoparticles in drug delivery. It also covers the integration of Artificial Intelligence and Machine Learning in pharmacokinetics and pharmacodynamics, showcasing how these cutting-edge approaches can enhance our understanding of drug behavior and optimize therapeutic outcomes. It serves as a comprehensive guide, highlighting the fusion of traditional pharmacological concepts with contemporary drug delivery systems and innovative technologies, all in the pursuit of refining medical treatments and patient care and is a valuable resource for academicians, researchers, and pharmacologists.
Nanoparticulate Drug Delivery Systems
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Author : Deepak Thassu
language : en
Publisher: CRC Press
Release Date : 2007-03-30
Nanoparticulate Drug Delivery Systems written by Deepak Thassu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-30 with Medical categories.
With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e
Drug Delivery
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Author : Binghe Wang
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-18
Drug Delivery written by Binghe Wang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-18 with Science categories.
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery
Nano Pharmacokinetics And Theranostics
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Author : Nanasaheb D. Thorat
language : en
Publisher: Academic Press
Release Date : 2021-07-28
Nano Pharmacokinetics And Theranostics written by Nanasaheb D. Thorat and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-28 with Business & Economics categories.
Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics Describes assessment methods of nano-pharmacokinetics Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer
Drug Delivery Systems
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Author : Kewal K. Jain
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-07
Drug Delivery Systems written by Kewal K. Jain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-07 with Science categories.
In this concise and systematic book, a team of experts select the most important, cutting-edge technologies used in drug delivery systems. They take into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular BiologyTM series format, offering readily reproducible results vital for pharmaceutical physicians and scientists.
Advances In Nanotechnology Based Drug Delivery Systems
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Author : Anupam Das Talukdar
language : en
Publisher: Elsevier
Release Date : 2022-06-06
Advances In Nanotechnology Based Drug Delivery Systems written by Anupam Das Talukdar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-06 with Technology & Engineering categories.
Advances in Nanotechnology-Based Drug Delivery Systems covers the core concepts and latest research regarding the use of nanoscale materials for the development and application of drug delivery systems. The book introduces the reader to nanotechnology in drug delivery, covering the synthesis, encapsulation techniques, characterization and key properties of nanoscale drug delivery systems. Later chapters review the broad range of target applications, including site-specific delivery of drugs for cardiovascular disease, cancer, bacterial infection, bone regeneration. and much more. This book helps translate advanced research into a clinical setting, analyzing the toxicity and health and safety challenges associated with utilizing nanotechnology in biomedicine. This will be a useful reference for those interested in nano-sized drug delivery in biomedicine, including academics and researchers in materials science, biomedical engineering, pharmaceutical science and related disciplines. Provides a clear introduction to nanotechnology in drug delivery, covering key principles, synthesis, characterization and unique properties of nanoscale materials for drug delivery systems“/li> Discusses preclinical, clinical and patented nano-drug delivery systems, enabling the reader to grasp the current state-of-the-art and market Covers a broad range of targets for nanoscale drug delivery systems, such as in neurological disorders, oral disease, renal disease, cancer, skin protection, and much more
Nanoparticulates As Drug Carriers
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Author : V. P. Torchilin
language : en
Publisher: Imperial College Press
Release Date : 2006
Nanoparticulates As Drug Carriers written by V. P. Torchilin and has been published by Imperial College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Technology & Engineering categories.
Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposomal Drug Carriers in Cancer Therapy (A A Gabizon); Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw); Nanoparticles for Targeting Lymphatics (W Phillips); Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso); and other papers. Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging."
Surface Modification Of Nanoparticles For Targeted Drug Delivery
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Author : Yashwant V Pathak
language : en
Publisher: Springer
Release Date : 2019-03-11
Surface Modification Of Nanoparticles For Targeted Drug Delivery written by Yashwant V Pathak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-11 with Medical categories.
This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.