A Structures Primer

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Author : Harry F. Kaufman
Genre : Structural analysis (Engineering)

Summary : This introductory paperback takes an informal approach to introducing "allowable stress" structures to users who need to understand basic structures but don't necessarily plan to become engineers. The book does not cover calculus and complex theory yet provides students with the understanding of the fundamental structural concepts required of their respective professions. The book features nearly 400 high-quality graphics that help users grasp key concepts. This can be used as a professional resource for construction managers, architects, or anyone interested in construction technology.

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Author : James E. Ambrose
Genre : Structural analysis (Engineering)

Summary :

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Author : Ramsey Dabby
Genre : Architecture

Summary : An introduction to the concepts and principles of architectural structures in an easy-to-read format Written as an easy-to-understand primer on the topic, Structure for Architects engages readers through instruction that uses a highly visual format and real-world examples to underline the key facets of structural principles that are essential to the design process. Eschewing complicated mathematics and technical jargon, Structure for Architects demystifies the subject matter by showing it in the context of everyday situations, giving architects and architectural technologists a clear understanding of how to incorporate structural principles into their designs. Highlights of this book include: A rich collection of drawings, photographs, and diagrams, spread throughout the text, which demonstrate fundamental structural concepts using everyday examples An overview of structural design basics, as well as a summary of structural forms A look at the design implications of steel, reinforced concrete, and wood By providing an overall view of structures that covers the essentials of what architects and architectural technologists need to know, Structure for Architects is a valuable tool for illustrating the importance of designing with structure in mind and for learning the basics that are necessary for collaborating confidently with project team members.

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Author : Thomas A Steitz
Genre : Science

Summary : Several years ago, Thomas Steitz agreed to contribute a volume to the 'World Scientific Series in Structural Biology' that would deal with the contributions he and his coworkers have made to structural biology during his remarkable career. Sadly, Tom died in the fall of 2018 before he had had time to do more than produce an outline for this book, and a list of the reprints he wanted it to contain.Fortunately, Tom's colleagues and coworkers responded enthusiastically when they were informed later that fall that if they were willing to help out, a volume would be published to commemorate his career. It fell to Anders Liljas, Peggy Eatherton, Tom's longtime administrative assistant, and Peter Moore, a close colleague, to oversee their efforts. Thomas Steitz is best known for the work he and his coworkers did to elucidate the biochemical basis of gene expression. The structures of a large number of the macromolecules involved in transcription and translation emerged from his laboratory over the course of his career. This book includes reprints of the most important papers he had published, grouped according to the structures they relate to, and commentaries written by the scientists who collaborated with him to solve each of them. It thus summarizes the achievements of one of the most distinguished biochemists of the second half of the 20th century.

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Author : Stuart MacNeill
Genre : Medical

Summary : High-fidelity chromosomal DNA replication underpins all life on the planet. In humans, there are clear links between chromosome replication defects and genome instability, genetic disease and cancer, making a detailed understanding of the molecular mechanisms of genome duplication vital for future advances in diagnosis and treatment. Building on recent exciting advances in protein structure determination, the book will take the reader on a guided journey through the intricate molecular machinery of eukaryotic chromosome replication and provide an invaluable source of information, ideas and inspiration for all those with an interest in chromosome replication, whether from a basic science, translational biology and medical research perspective.

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Author : M Tevfik Dorak
Genre : Science

Summary : With a variety of detection chemistries, an increasing number of platforms, multiple choices for analytical methods and the jargon emerging along with these developments, real-time PCR is facing the risk of becoming an intimidating method, especially for beginners. Real-time PCR provides the basics, explains how they are exploited to run a real-time PCR assay, how the assays are run and where these assays are informative in real life. It addresses the most practical aspects of the techniques with the emphasis on 'how to do it in the laboratory'. Keeping with the spirit of the Advanced Methods Series, most chapters provide an experimental protocol as an example of a specific assay.

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Author : John M. S. Bartlett
Genre : Science

Summary : In this new edition, the editors have thoroughly updated and dramatically expanded the number of protocols to take advantage of the newest technologies used in all branches of research and clinical medicine today. These proven methods include real time PCR, SNP analysis, nested PCR, direct PCR, and long range PCR. Among the highlights are chapters on genome profiling by SAGE, differential display and chip technologies, the amplification of whole genome DNA by random degenerate oligonucleotide PCR, and the refinement of PCR methods for the analysis of fragmented DNA from fixed tissues. Each fully tested protocol is described in step-by-step detail by an established expert in the field and includes a background introduction outlining the principle behind the technique, equipment and reagent lists, tips on trouble shooting and avoiding known pitfalls, and, where needed, a discussion of the interpretation and use of results.