101 Regras B Sicas Para Edificios E Cidades Susten
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Our Common Future
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Author :
language : en
Publisher:
Release Date : 1990
Our Common Future written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Australia categories.
Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Dependency And Development In Latin America
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Author : Fernando Henrique Cardoso
language : en
Publisher: Univ of California Press
Release Date : 2024-03-29
Dependency And Development In Latin America written by Fernando Henrique Cardoso and has been published by Univ of California Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-29 with History categories.
At the end of World War II, several Latin American countries seemed to be ready for industrialization and self-sustaining economic growth. Instead, they found that they had exchanged old forms of political and economic dependence for a new kind of dependency on the international capitalism of multinational corporations. In the much-acclaimed original Spanish edition (Dependencia y Desarrollo en América Latina) and now in the expanded and revised English version, Cardoso and Faletto offer a sophisticated analysis of the economic development of Latin America. The economic dependency of Latin America stems not merely from the domination of the world market over internal national and "enclave" economies, but also from the much more complex interact ion of economic drives, political structures, social movements, and historically conditioned alliances. While heeding the unique histories of individual nations, the authors discern four general stages in Latin America's economic development: the early outward expansion of newly independent nations, the political emergence of the middle sector, the formation of internal markets in response to population growth, and the new dependence on international markets. In a postscript for this edition, Cardoso and Faletto examine the political, social and economic changes of the past ten years in light of their original hypotheses.
Resilient Sustainable Cities
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Author : Leonie Pearson
language : en
Publisher: Routledge
Release Date : 2014-01-10
Resilient Sustainable Cities written by Leonie Pearson and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-10 with Architecture categories.
Urbanization is occurring at an unprecedented rate; by 2050 three quarters of the world’s people will live in urban environments. The cars we drive, products we consume, houses we live in and technology we use will all determine how sustainable our cities will be. Bridging the increasing divide between cross-disciplinary academic insights and the latest practical innovations, Resilient Sustainable Cities provides an integrated approach for long term future planning within the context of the city as a whole system. In the next 30 years cities will face their biggest challenges yet, as a result of long term, or ‘slow burn’ issues: population growth will stretch to the breaking point urban infrastructure and service capacity; resource scarcity, such as peak oil; potable water and food security, will dramatically change what we consume and how; environmental pressures will change how we live and where and; shifting demographic preferences will exacerbate urban pressures. Cities can’t keep doing what they’ve always done and cope – we need to change current urban development to achieve resilient, sustainable cities. Resilient Sustainable Cities provides practical and conceptual insights for practitioners, researchers and students on how to deliver cities which are resilient to ‘slow burn’ issues and achieve sustainability. The book is organized around three overarching themes: pathways to the future innovation to deliver the future leadership and governance issues The book includes a variety of perspectives conveyed through international case studies and examples of cities that have transformed for a sustainable future, exploring their successes and failures to ensure that readers are left with ideas on how to turn their city into a resilient sustainable city for the future.
Asylums
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Author : Erving Goffman
language : en
Publisher: Routledge
Release Date : 2017-09-08
Asylums written by Erving Goffman and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-08 with Social Science categories.
A total institution is defined by Goffman as a place of residence and work where a large number of like-situated, individuals, cut off from the wider society for an appreciable period of time, together lead an enclosed, formally administered round of life. Prisons serve as a clear example, providing we appreciate that what is prison-like about prisons is found in institutions whose members have broken no laws. This volume deals with total institutions in general and, mental hospitals, in particular. The main focus is, on the world of the inmate, not the world of the staff. A chief concern is to develop a sociological version of the structure of the self. Each of the essays in this book were intended to focus on the same issue--the inmate's situation in an institutional context. Each chapter approaches the central issue from a different vantage point, each introduction drawing upon a different source in sociology and having little direct relation to the other chapters. This method of presenting material may be irksome, but it allows the reader to pursue the main theme of each paper analytically and comparatively past the point that would be allowable in chapters of an integrated book. If sociological concepts are to be treated with affection, each must be traced back to where it best applies, followed from there wherever it seems to lead, and pressed to disclose the rest of its family.
Smart City Implementation
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Author : Renata Paola Dameri
language : en
Publisher: Springer
Release Date : 2016-09-15
Smart City Implementation written by Renata Paola Dameri and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-15 with Business & Economics categories.
In a series of essays, this book describes and analyzes the concept and theory of the recent smart city phenomenon from a global perspective, with a focus on its implementation around the world. After defining the concept it then elaborates on the role of Information and Communication Technology (ICT) as an enabler for smart cities, and the role of ICT in the interplay with smart mobility. A separate chapter develops the concept of an urban smart dashboard for stakeholders to measure performance as well as the economic and public value. It offers examples of smart cities around the globe, and two detailed case studies on Genoa and Amsterdam exemplify the book’s theoretical and empirical findings, helping readers understand and evaluate the effectiveness and capability of new smart city programs.
Pedagogy Of Praxis
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Author : Moacir Gadotti
language : en
Publisher: SUNY Press
Release Date : 1996-01-01
Pedagogy Of Praxis written by Moacir Gadotti and has been published by SUNY Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-01 with Education categories.
Presents a critical, Neo-Marxist philosophy of education.
Cities For People
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Author : Jan Gehl
language : en
Publisher: Island Press
Release Date : 2013-03-05
Cities For People written by Jan Gehl and has been published by Island Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-05 with Architecture categories.
For more than forty years Jan Gehl has helped to transform urban environments around the world based on his research into the ways people actually use—or could use—the spaces where they live and work. In this revolutionary book, Gehl presents his latest work creating (or recreating) cityscapes on a human scale. He clearly explains the methods and tools he uses to reconfigure unworkable cityscapes into the landscapes he believes they should be: cities for people. Taking into account changing demographics and changing lifestyles, Gehl emphasizes four human issues that he sees as essential to successful city planning. He explains how to develop cities that are Lively, Safe, Sustainable, and Healthy. Focusing on these issues leads Gehl to think of even the largest city on a very small scale. For Gehl, the urban landscape must be considered through the five human senses and experienced at the speed of walking rather than at the speed of riding in a car or bus or train. This small-scale view, he argues, is too frequently neglected in contemporary projects. In a final chapter, Gehl makes a plea for city planning on a human scale in the fast- growing cities of developing countries. A “Toolbox,” presenting key principles, overviews of methods, and keyword lists, concludes the book. The book is extensively illustrated with over 700 photos and drawings of examples from Gehl’s work around the globe.
Housing In Urban Britain 1780 1914
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Author : Richard Rodger
language : en
Publisher: Cambridge University Press
Release Date : 1995-09-14
Housing In Urban Britain 1780 1914 written by Richard Rodger and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-09-14 with Business & Economics categories.
Why did slums and suburbs develop simultaneously? Did the capitalist system produce these, and were class antagonisms to blame? Why did the Victorians believe there was a housing problem, and who or what created it? What housing solutions were attempted, and how successfully? These are amongst the central questions addressed by social and urban historians in recent years, and their arguments and analyses are reviewed here. The history of housing between 1780 and 1914 encapsulates many problems associated with the transition from a largely rural to an overwhelmingly urban nation. The unprecedented pace of this transition imposed immense tensions within society, with implications for the urban environment and for local and national government. Housing is central to an understanding of the social, economic, political and cultural forces in nineteenth-century history; this book is an ideal introduction to the topic.
The Role Of Ecosystems In Disaster Risk Reduction
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Author : Fabrice G. Renaud
language : en
Publisher: United Nations University Press
Release Date : 2013
The Role Of Ecosystems In Disaster Risk Reduction written by Fabrice G. Renaud and has been published by United Nations University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Nature categories.
The uptake of ecosystem-based approaches for disaster risk reduction (DRR) is slow, however, despite some success stories. There are multiple reasons for this reluctance: ecosystem management is rarely considered as part of the portfolio of DRR solutions because the environmental and disaster management communities typically work independently from each other; its contribution to DRR is highly undervalued compared to engineered solutions and therefore not given appropriate budget allocations; and there are poor interactions between policymakers and researchers, leading to unclear and sometimes contradictory scientific information on the role of ecosystems for DRR. The aim of this book is to provide an overview of knowledge and practice in this multidisciplinary field of ecosystems management and DRR. The contributors, professionals from the science and disaster management communities around the world, represent state-of-the-art knowledge, practices, and perspectives on the topic.