A Cidade Polif Nica
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
The War Of Dreams
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Author : Marc Auge
language : en
Publisher: Pluto Press
Release Date : 1999-06-20
The War Of Dreams written by Marc Auge and has been published by Pluto Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-06-20 with Literary Criticism categories.
Continues Augé's critical exploration of contemporary modernity with an examination of the role of dreams, myth and fiction in the age of satellite TV and the Internet.
O Crime Do Padre Amaro A Cidade E As Serras Prosas B Rbaras Contos O Primo Basilio A Ilustre Casa De Ramires O Mandarim A Rel Quia
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Author : Eça de Queirós
language : es
Publisher:
Release Date : 1958
O Crime Do Padre Amaro A Cidade E As Serras Prosas B Rbaras Contos O Primo Basilio A Ilustre Casa De Ramires O Mandarim A Rel Quia written by Eça de Queirós and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1958 with categories.
The Blackwell Companion To The Sociology Of Culture
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Author : Mark D. Jacobs
language : en
Publisher: John Wiley & Sons
Release Date : 2016-09-26
The Blackwell Companion To The Sociology Of Culture written by Mark D. Jacobs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-26 with Social Science categories.
This collection of original, state-of-the-art essays by prominent international scholars covers the most important issues comprising the sociology of culture. Provides an invaluable reference resource to all interested in the cultural structures and processes that animate contemporary life Contains 27 essays on the most important issues comprising the sociology of culture, including art, science, religions, race, class, gender, collective memory, institutions, and citizenship Reflects and analyzes the “cultural turn” that has transformed scholarship in the social sciences and humanities.
A Tropical Belle Epoque
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Author : Jeffrey D. Needell
language : en
Publisher: Cambridge University Press
Release Date : 1987
A Tropical Belle Epoque written by Jeffrey D. Needell and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with History categories.
This book, originally published in 1987, is a socio-cultural analysis of a tropical belle epoque: Rio de Janeiro between 1898 and 1914. It relates how the city's elite evolved from the semi-rural, slave-owning patriarchy of the coffee-port seat of a monarchy into an urbane, professional, rentier upper crust dominating the centre of a 'modernising' oligarchical republic. It explores such varied topics as architecture, literature, prostitution, urban reform, the family, secondary schools, and the salon. It evokes a milieu increasingly marked by Europe, demonstrating how French and English culture permeated the lives of elite members who adapted it to their needs and perspectives as a dominant stratum of relatively recent and varied origin. This exploration of cultural 'dependency' in a unique, cosmopolitan, fin-de-siecle urban culture will also interest those concerned with the broader questions of culture and colonialism during the high tide of European imperialism.
Geology Of Southwest Gondwana
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Author : Siegfried Siegesmund
language : en
Publisher: Springer
Release Date : 2018-02-02
Geology Of Southwest Gondwana written by Siegfried Siegesmund and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-02 with Science categories.
This book focuses on the geological evolution of Southwest (SW) Gondwana and presents state-of-the-art insights into its evolution. It addresses the diachronic assembly of continental fragments derived from the break-up of the Rodinia supercontinent later amalgamated to build SW Gondwana during the Neoproterozoic–Cambrian transition, which on a global scale includes parts of present-day South America, Africa and Madagascar. The book presents 24 state-of-the-art reviews including the most crucial controversies. Most experienced scientists about the geology of SW Gondwana from Europe, Africa, South America and Australia present contributions on key areas addressing the interactions between the main cratons and fold belts on both sides of the South Atlantic Ocean. Chapters related to the geology of the major Archean- Paleoproterozoic cratons and Neoproterozoic Brasiliano/Pan-African fold belts enable readers to gain an in-depth understanding of the tectonometamorphic and magmatic evolution of SW Gondwana. The book covers a wide range of issues including metallogenetic, sedimentary, paleobiological and paleoclimatic processes and allows a deep insight into this key period of the Earth’s evolution.
Brasil Medico
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Author :
language : pt-BR
Publisher:
Release Date : 1942
Brasil Medico written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1942 with categories.
Understanding News
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Author : John Hartley
language : en
Publisher: Routledge
Release Date : 2013-06-17
Understanding News written by John Hartley and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-17 with Social Science categories.
News depends for its effect on a culturally shared language, and this book concentrates on ways we can decode its messages without simply reproducing their underlying assumptions.
Dark Side Of The Tune
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Author : Bruce Johnson
language : en
Publisher: Ashgate Publishing, Ltd.
Release Date : 2009
Dark Side Of The Tune written by Bruce Johnson and has been published by Ashgate Publishing, Ltd. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Music categories.
This book focuses on the 'dark side' of popular music by examining the ways in which popular music has been deployed in association with violence. Cloonan and Johnson address the physiological and cognitive foundations of sounding/hearing and provide a historical survey of examples of the nexus between music and violence, from (pre)Biblical times to the late nineteenth century. The book also concentrates on the emergence of technologies by which music can be electronically augmented, generated, and disseminated. The authors investigate the implications of this nexus both for popular music studies itself, and also in cultural policy and regulation, the ethics of citizenship, and arguments about human rights.
Pedagogy Of Praxis
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Author : Moacir Gadotti
language : en
Publisher: SUNY Press
Release Date : 1996-01-01
Pedagogy Of Praxis written by Moacir Gadotti and has been published by SUNY Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-01-01 with Education categories.
Presents a critical, Neo-Marxist philosophy of education.