A Esperan A Utopia Imposs Vel

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Restoration

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Author : Rose Tremain
language : en
Publisher: W. W. Norton & Company
Release Date : 2013-04-15

Restoration written by Rose Tremain and has been published by W. W. Norton & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-15 with Fiction categories.

Restoration is a dazzling romp through 17th-century England. The main character Robert Merivel not only embodies the contradictions of his era, but ours as well. He is trapped between the longing for wealth and power and the realization that the pursuit of these trappings can leave one's life rather empty.

Translational Medicine

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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26

Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.

Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

World Literature Cosmopolitanism Globality

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Author : Gesine Müller
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-10-21

World Literature Cosmopolitanism Globality written by Gesine Müller and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-21 with Foreign Language Study categories.

From today’s vantage point it can be denied that the confidence in the abilities of globalism, mobility, and cosmopolitanism to illuminate cultural signification processes of our time has been severely shaken. In the face of this crisis, a key concept of this globalizing optimism as World Literature has been for the past twenty years necessarily is in the need of a comprehensive revision. World Literature, Cosmopolitanism, Globality: Beyond, Against, Post, Otherwise offers a wide range of contributions approaching the blind spots of the globally oriented Humanities for phenomena that in one way or another have gone beyond the discourses, aesthetics, and political positions of liberal cosmopolitanism and neoliberal globalization. Departing basically (but not exclusively) from different examples of Latin American literatures and cultures in globalized contexts, this volume provides innovative insights into critical readings of World Literature and its related conceptualizations. A timely book that embraces highly innovative perspectives, it will be a mustread for all scholars involved in the field of the global dimensions of literature.

Caciques And Cemi Idols

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Author : José R. Oliver
language : en
Publisher: University of Alabama Press
Release Date : 2009-05-10

Caciques And Cemi Idols written by José R. Oliver and has been published by University of Alabama Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-10 with History categories.

Takes a close look at the relationship between humans and other (non-human) beings that are imbued with cemí power, specifically within the Taíno inter-island cultural sphere encompassing Puerto Rico and Hispaniola Cemís are both portable artifacts and embodiments of persons or spirit, which the Taínos and other natives of the Greater Antilles (ca. AD 1000-1550) regarded as numinous beings with supernatural or magic powers. This volume takes a close look at the relationship between humans and other (non-human) beings that are imbued with cemí power, specifically within the Taíno inter-island cultural sphere encompassing Puerto Rico and Hispaniola. The relationships address the important questions of identity and personhood of the cemí icons and their human “owners” and the implications of cemí gift-giving and gift-taking that sustains a complex web of relationships between caciques (chiefs) of Puerto Rico and Hispaniola. Oliver provides a careful analysis of the four major forms of cemís—three-pointed stones, large stone heads, stone collars, and elbow stones—as well as face masks, which provide an interesting contrast to the stone heads. He finds evidence for his interpretation of human and cemí interactions from a critical review of 16th-century Spanish ethnohistoric documents, especially the Relación Acerca de las Antigüedades de los Indios written by Friar Ramón Pané in 1497–1498 under orders from Christopher Columbus. Buttressed by examples of native resistance and syncretism, the volume discusses the iconoclastic conflicts and the relationship between the icons and the human beings. Focusing on this and on the various contexts in which the relationships were enacted, Oliver reveals how the cemís were central to the exercise of native political power. Such cemís were considered a direct threat to the hegemony of the Spanish conquerors, as these potent objects were seen as allies in the native resistance to the onslaught of Christendom with its icons of saints and virgins.

Outline Of The Principles Of History

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Author : Johann Gustav Droysen
language : id
Publisher:
Release Date : 1897

Outline Of The Principles Of History written by Johann Gustav Droysen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1897 with History categories.

Toward Liberty

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Author : Friedrich August Hayek
language : en
Publisher:
Release Date : 1973

Toward Liberty written by Friedrich August Hayek and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with categories.

Beyond Development

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Author : Miriam Lang
language : en
Publisher:
Release Date : 2013

Beyond Development written by Miriam Lang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Latin America categories.

Happiness And Utility

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Author : Georgios Varouxakis
language : en
Publisher: UCL Press
Release Date : 2019-07-29

Happiness And Utility written by Georgios Varouxakis and has been published by UCL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-29 with Philosophy categories.

Happiness and Utility brings together experts on utilitarianism to explore the concept of happiness within the utilitarian tradition, situating it in earlier eighteenth-century thinkers and working through some of its developments at the end of the nineteenth and beginning of the twentieth centuries. Drawing on a range of philosophical and historical approaches to the study of the central idea of utilitarianism, the chapters provide a rich set of insights into a founding component of ethics and modern political and economic thought, as well as political and economic practice. In doing so, the chapters examine the multiple dimensions of utilitarianism and the contested interpretations of this standard for judgement in morality and public policy.

Xtremus A Bionican Quest In The Wake Of Cybergeddon

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Author : Peter Wiesner
language : en
Publisher: Montag Press
Release Date : 2015-04-27

Xtremus A Bionican Quest In The Wake Of Cybergeddon written by Peter Wiesner and has been published by Montag Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-27 with Humor categories.

Xtremus is a dystopian satire about the aftermath of a cataclysmic demise of technology that takes place in post-apocalyptic Southern California. Eco terrorists have unleashed a computer virus killing the ruling class whose power and life force were dependent on sophisticated brain implants through which they communicated and held sway. The story follows the quest of Condor, leader of a group of "hackers" who survived Cybergeddon because of the immunities they received, albeit without the firepower of the halcyon days of techno splendor. Condor and other "hackers" are sworn to protect The Well, the only remaining database from the high-technology past that now resides in brains of the Bionicans. Condor's mission is to determine whether The Well's secret database could be hacked by other survivors outside of Bionica to develop weapons of mass destruction and wreak havoc again. Condor's quest obliges him to deal with all three surviving clans in Southern California, each bent on imposing their unique ideology in this post-apocalyptic world: his fellow Bionicans, a drug besotted lot who communicate telepathically through The Well; the crude and romantic Goths, who love gladiatorial combat and motorcycles, and treat bad poetry as a capital crime; and the decadent Greeks whose work to revive of the Classics from Homer to Plato is supported by slavery and guided by sexual politics. Condor's quest is transformed many times by the women he conquers and manipulated by the woman who finally conquers him. His exploits turn into a power-grabbing adventure of murder, intrigue, and betrayal. By the time he learns about the true nature of his quest, it is too late for our hero to prevail. Xtremus is a morality tale and a satire of the Information Age, as we now know it. It pokes fun at the ideological melange of the 1960's that gave rise to environmental awareness, consumerism, sexual freedom, gay liberation, vegans, Eastern religion, mythology, New Age healing, motorcycle-based rebellion, and drug-induced alternate states of consciousness. It also takes on those whose blue-sky tunnel vision of technology is painting our future into a corner where wildlife and civil society cannot thrive."

The Handbook Of Global Media And Communication Policy

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Author : Robin Mansell
language : en
Publisher: John Wiley & Sons
Release Date : 2014-03-03

The Handbook Of Global Media And Communication Policy written by Robin Mansell and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-03 with Social Science categories.

The Handbook of Global Media and Communication Policy offers insights into the boundaries of this field of study, assesses why it is important, who is affected, and with what political, economic, social and cultural consequences. Provides the most up to date and comprehensive collection of essays from top scholars in the field Includes contributions from western and eastern Europe, North and Central America, Africa and Asia Offers new conceptual frameworks and new methodologies for mapping the contours of emergent global media and communication policy Draws on theory and empirical research to offer multiple perspectives on the local, national, regional and global forums in which policy debate occurs