Abastecer La Obra G Tica

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Translational Medicine

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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26

Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.

Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Artificial Intelligence

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Author : Stuart Russell
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2016-09-10

Artificial Intelligence written by Stuart Russell and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-10 with categories.

Artificial Intelligence: A Modern Approach offers the most comprehensive, up-to-date introduction to the theory and practice of artificial intelligence. Number one in its field, this textbook is ideal for one or two-semester, undergraduate or graduate-level courses in Artificial Intelligence.

A History Of Reading In The West

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Author : Guglielmo Cavallo
language : en
Publisher: Polity
Release Date : 2003-08-15

A History Of Reading In The West written by Guglielmo Cavallo and has been published by Polity this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-15 with History categories.

This path-breaking study will become the standard work on thehistory of reading in the West. It will be indispensable tostudents of cultural history, and to all those who want a freshperspective on the history of books and their uses. Wide-ranging and authoritative account of the changingpractices of reading from the ancient world to the presentday. An international team of leading historians examine thetechnical innovations which change physical aspects of books andother texts, as well as the changing forms of reading and thegrowth and transformation of the reading public. Contributors include: Robert Bonfil, Guglielmo Cavallo, RogerChartier, Jean-Francois Gilmont, Anthony Grafton, JacquelineHamesse, Dominique Julia, Martyn Lyons, M.B. Parkes, ArmandoPetrucci, Paul Saenger, Jesper Svenbro and Reinhard Wittmann. This path-breaking study has been highly successful in hardbackand is now available in paperback for the first time.

Bolivia

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Author :
language : es
Publisher:
Release Date : 1963

Bolivia written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1963 with Bolivia categories.

Life In The Argentine Republic In The Days Of The Tyrants

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Author : Domingo Faustino Sarmiento
language : en
Publisher:
Release Date : 1868

Life In The Argentine Republic In The Days Of The Tyrants written by Domingo Faustino Sarmiento and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1868 with Argentina categories.

Actas

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Author : Argentina. Congreso de la Nación. Cámara de Diputados de la Nación
language : es
Publisher:
Release Date : 1954

Actas written by Argentina. Congreso de la Nación. Cámara de Diputados de la Nación and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1954 with categories.

Teor A De Las Condiciones Y Los Servicios Generales De La Producci N

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Author : Gustavo Garza
language : es
Publisher: El Colegio de Mexico AC
Release Date : 2013-06-17

Teor A De Las Condiciones Y Los Servicios Generales De La Producci N written by Gustavo Garza and has been published by El Colegio de Mexico AC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-17 with Business & Economics categories.

La economía política de la urbanización asume que las condiciones generales de la producción constituyen el determinante histórico fundamental de la concentración espacial del capital. En este libro, primero de una trilogía sobre el tema, se extiende esa categoría proponiendo la existencia del binomio condiciones y servicios generales de la producción, como un concepto más adecuado para comprender las aglomeraciones metropolitanas contemporáneas. En la primera parte de la obra se analiza la evolución de dicha categoría dentro de la teoría del capital, su desarrollo histórico mundial como andamiaje infraestructural, así como su definición, tipología y características. En la segunda parte se inicia un estudio empírico sobre el vínculo de la infraestructura con la competitividad urbana y, principalmente, la cuestión de su financiamiento en el caso de la Ciudad de México.

The United Nations World Water Development Report 2017

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Author : WWAP
language : en
Publisher: UNESCO Publishing
Release Date : 2017-03-15

The United Nations World Water Development Report 2017 written by WWAP and has been published by UNESCO Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-15 with Education categories.

The United Nations World Water Assessment Programme (WWAP) is hosted and led by UNESCO. WWAP brings together the work of 31 UN-Water Members and 38 Partners to publish The United Nations World Water Development Report, (WWDR) series. The annual World Water Development Reports focus on strategic water issues. UN-Water Members and Partners, all experts in their respective fields, contribute the latest findings on a specific theme. The 2017 edition of the World Water Development Report focuses on 'Wastewater' and seeks to inform decision-makers, inside and outside the water community, about the importance of managing wastewater as an undervalued and sustainable source of water, energy, nutrients and other recoverable by-products, rather than something to be disposed of or a nuisance to be ignored. The report's title - Wastewater: The Untapped Resource - reflects the critical role that wastewater is poised to play in the context of a circular economy, whereby economic development is balanced with the protection of natural resources and environmental sustainability, and where a cleaner and more sustainable economy has a positive effect on the water quality. Improved wastewater management is not only critical to achieving the Sustainable Development Goal on clean water and sanitation (SDG 6), but also to other goals of the 2030 Agenda for Sustainable Development.

Anales De La C Tedra Francisco Su Rez

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Author :
language : es
Publisher:
Release Date :

Anales De La C Tedra Francisco Su Rez written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Law categories.

Acta

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Author : Argentina. Congreso de la Nación. Senado de la Nación
language : es
Publisher:
Release Date : 1954

Acta written by Argentina. Congreso de la Nación. Senado de la Nación and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1954 with Argentina categories.