As Rela Es Perigosas
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Boletim
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Author : Sociedade Brasileira de Geografia
language : en
Publisher:
Release Date : 1892
Boletim written by Sociedade Brasileira de Geografia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1892 with Geography categories.
Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Annaes Do Parlamento Brazileiro
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Author : Brazil. Parlamento. Câmara dos Srs. Deputados
language : pt-BR
Publisher:
Release Date : 1888
Annaes Do Parlamento Brazileiro written by Brazil. Parlamento. Câmara dos Srs. Deputados and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1888 with Brazil categories.
Anais
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Author : Brazil. Congresso Nacional. Câmara dos Deputados
language : pt-BR
Publisher:
Release Date : 1888
Anais written by Brazil. Congresso Nacional. Câmara dos Deputados and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1888 with categories.
Perigosa Mente
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Author : Cininha Maciel E Herval Machado Costa
language : pt-BR
Publisher: Clube de Autores
Release Date : 2019-07-06
Perigosa Mente written by Cininha Maciel E Herval Machado Costa and has been published by Clube de Autores this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-06 with Drama categories.
Uma história fictícia escrita a quatro mãos pela escritora Cininha Maciel e pelo jornalista e advogado Herval Machado. Ela é ambientada a partir dos anos trinta. Fala de vários crimes cometidos por uma pessoa de dupla personalidade que ao mesmo tempo que amava, também odiava em nome desse amor ou também por uma grande amizade. A história envolve o personagem Wilson Cordeiro Junior. As primeiras páginas já prendem a atenção do leitor : porque será que o Junior foi preso? Vamos deixar que os leitores viagem nesta história, através da violência doméstica, trabalho infantil, prostituição, homicídios, drogas, guerra, preconceito, amores proibidos e também de espiritualidade. Não deixem de ler. É uma viagem no tempo.
Revista Universal Lisbonense
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Author :
language : pt-BR
Publisher:
Release Date : 1850
Revista Universal Lisbonense written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1850 with categories.
Sonhar Restaurado O
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Author : Ab’Sáber, Tales A. M.
language : pt-BR
Publisher: Editora 34
Release Date : 2005
Sonhar Restaurado O written by Ab’Sáber, Tales A. M. and has been published by Editora 34 this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Psychology categories.
O sonhar restaurado alterna os relatos de três casos vivenciados pelo autor em sua experiência clínica - voltada em grande parte à restauração da capacidade de sonhar - com três ensaios teóricos, dedicados a W. Bion, D. Winnicott e Sigmund Freud, que discutem em detalhe e profundidade seus conceitos e práticas, ao mesmo tempo em que analisam a evolução da disciplina a partir de suas obras fundamentais.
A Constru O Po Tica Do Real
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Author :
language : pt-BR
Publisher: 7Letras
Release Date : 2004
A Constru O Po Tica Do Real written by and has been published by 7Letras this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Literature categories.
Quest Es Laborais N O 57
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Author : Associação de Estudos Laborais
language : pt-BR
Publisher: Leya
Release Date : 2023-06-05
Quest Es Laborais N O 57 written by Associação de Estudos Laborais and has been published by Leya this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-05 with Law categories.
Publicada desde 1994, a Questões Laborais tem constituído uma referência singular na literatura e jurisprudência laborais do nosso país, bem assim como uma demonstração de persistência da entidade responsável pela sua publicação, a Associação de Estudos Laborais (ael), em prol do estudo e do reconhecimento do Direito do Trabalho. A AEL nunca deixou de se empenhar no cumprimento de um dos seus objetivos principais: a publicação de uma revista independente sem outras preocupações que não sejam o estudo, com objetividade e rigor, do Direito do Trabalho. Tem cumprido - e propõe-se continuar a cumprir, nesta nova fase da sua vida - o seu desiderato, congregando, na Questões Laborais, escritos diversificados, de valia prática e teórica, expressando perspetivas e posições de largo espectro ideológico, profissional e doutrinário. Greve e substituição de grevistas Greve e serviços mínimos Reorganização societária e estruturas de representação coletiva Uberização do contrato de trabalho e a subordinação jurídica Regime dos acidentes de trabalho Trabalho temporário e segurança e saúde laborais Teletrabalho e direito à desconexão Contrato de trabalho com treinador desportivo Relação laboral desportiva: o caso Rafael Leão
Palmerin Of England
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Author : Francisco de Morais
language : en
Publisher: London, Longman, Hurst, Rees and Orme
Release Date : 1807
Palmerin Of England written by Francisco de Morais and has been published by London, Longman, Hurst, Rees and Orme this book supported file pdf, txt, epub, kindle and other format this book has been release on 1807 with Palmerin of England (Romance) categories.