C Digo Dos Milion Rios
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Government At A Glance Latin America And The Caribbean 2017
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2016-12-06
Government At A Glance Latin America And The Caribbean 2017 written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-06 with categories.
This second edition of Government at a Glance: Latin America and the Caribbean provides the latest available data on public administrations in the LAC region and compares it to OECD countries.
Slavery In Brazil
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Author : Herbert S. Klein
language : en
Publisher: Cambridge University Press
Release Date : 2010
Slavery In Brazil written by Herbert S. Klein and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with History categories.
This is the first complete modern survey of the institution of slavery in Brazil and how it affected the lives of enslaved Africans. It is based on major new research on the institution of slavery and the role of Africans and their descendants in Brazil. This book aims to introduce the reader to this latest research, both to elucidate the Brazilian experience and to provide a basis for comparisons with all other American slave systems.
To Your Scattered Bodies Go
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Author : Philip Jose Farmer
language : en
Publisher: Hachette UK
Release Date : 2013-01-24
To Your Scattered Bodies Go written by Philip Jose Farmer and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-24 with Fiction categories.
All those who ever lived on Earth have found themselves resurrected - healthy, young, and naked as newborns - on the grassy banks of a mighty river, in a world unknown. Miraculously provided with food, but with no clues to the meaning of their strange new afterlife, billions of people from every period of Earth's history - and prehistory - must start again. Sir Richard Francis Burton would be the first to glimpse the incredible way-station, a link between worlds. This forbidden sight would spur the renowned 19th-century explorer to uncover the truth. Along with a remarkable group of compatriots, including Alice Liddell Hargreaves (the Victorian girl who was the inspiration for Alice in Wonderland), an English-speaking Neanderthal, a WWII Holocaust survivor, and a wise extraterrestrial, Burton sets sail on the magnificent river. His mission: to confront humankind's mysterious benefactors, and learn the true purpose - innocent or evil - of the Riverworld . . . Winner of the Hugo Award for best novel, 1972
Urban Literacy
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Author : Unesco Institute for Education
language : en
Publisher: UNESCO
Release Date : 2005
Urban Literacy written by Unesco Institute for Education and has been published by UNESCO this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Education categories.
Over 800 million adults worldwide, two thirds of them women, are unable to reap the benefits of literate expression. In this book, the author aims to dispel the notion that illiteracy is principally confined to rural areas, which has for many years been the main focus of development programmes. Through a series of case studies and analysis this book provides a valuable insight into what literacy can mean in an urban setting and explores the many ways it is used to enhance the lives of individuals. It highlights the need for greater understanding of the diversity of literacy learning and explores the practical issues in providing assistance to those who aspire to improve their literacy skills.
Opera In The Tropics
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Author : Rogério Budasz
language : en
Publisher: Oxford University Press
Release Date : 2019-03-22
Opera In The Tropics written by Rogério Budasz and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-22 with Music categories.
Opera in the Tropics is an engaging exploration of theater with music in Brazil from the mid 1500s to the early 1820s. Author Rogério Budasz delves into the practices of the actors, singers, poets, and composers who created and performed Jesuit moral plays, Spanish comedias, and Portuguese vernacular operas and entremezes during the colonial period, as well as the Italian operas that celebrated the new independent nation in 1822. A Brazilian producer claimed in 1825 that the goal of music-theater was to instruct, entertain, and distract the population. Budasz argues that this threefold goal had in fact been present throughout the colonial period, in different combinations and with different purposes, at the hands of missionaries, intellectuals, bureaucrats, political leaders, and cultural producers. While Budasz demonstrates a continuity from Portuguese theatrical practices, primarily through the circulation of artists and repertory, he also examines a number of localized departures from the metropolitan model, particularly in the ethnic and gender profile of theatrical workers, in the modifications determined by local tastes, priorities, and materials, and in the political use of theater as an ideological and civilizing tool within the paradoxical context of a slave society. An eye-opening narrative of the transformations and uses of a colonial art form, Opera in the Tropics will be essential reading for all interested in the music and theater in Iberian and Latin American culture.
Art Geeks And Prom Queens
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Author : Alyson Noël
language : en
Publisher: St. Martin's Griffin
Release Date : 2007-04-01
Art Geeks And Prom Queens written by Alyson Noël and has been published by St. Martin's Griffin this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-01 with Young Adult Fiction categories.
Dorks, Dweebs, Debutantes, and Jocks—Where would you fit in? Being the new girl is tough—just ask sixteen-year-old Rio Jones. A New York transplant, Rio has no clue how she's going to fit in at her fancy new private school in Southern California. Plus, being late, overdressed, and named after a Duran Duran song doesn't make the first day any easier for her. Then Rio meets Kristi. Beautiful, rich, and a cheerleader, Kristi is the queen bee of Newport Beach. And Kristi isn't friends with just anyone, so Rio is thrilled when she's invited to be part of the most exclusive, popular clique. Of course, like any club, Kristi and her friends have rules: Always smile (even if you don't mean it), always dress cute (and never repeat outfits), and always flirt (but only with jocks, preps, and rich college guys). At first Rio is having a great time, but as she becomes more immersed in this jet-set crowd, she figures out there is one last rule that her new friends forgot to mention: Don't cross Kristi . . . in Alyson Noël's Art Geeks and Prom Queens.
Borderlands
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Author : Gloria Anzaldúa
language : en
Publisher:
Release Date : 2021
Borderlands written by Gloria Anzaldúa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Literary Criticism categories.
Literary Nonfiction. Poetry. Latinx Studies. LGBTQIA Studies. Edited by Ricardo F. Vivancos-Pèrez and Norma Cantú. Rooted in Gloria Anzaldúa's experiences growing up near the U.S./Mexico border, BORDERLANDS/LA FRONTERA remaps our understanding of borders as psychic, social, and cultural terrains that we inhabit and that inhabit us all. Drawing heavily on archival research and a comprehensive literature review while contextualizing the book within her theories and writings before and after its 1987 publication, this critical edition elucidates Anzaldúa's complex composition process and its centrality in the development of her philosophy. It opens with two introductory studies; offers a corrected text, explanatory footnotes, translations, and four archival appendices; and closes with an updated bibliography of Anzaldúa's works, an extensive scholarly bibliography on Borderlands, a brief biography, and a short discussion of the Gloria E. Anzaldúa Papers. "Ricardo F. Vivancos-Pèrez's meticulous archival work and Norma Elia Cantú's life experience and expertise converge to offer a stunning resource for Anzaldúa scholars; for writers, artists, and activists inspired by her work; and for everyone. Hereafter, no study of Borderlands will be complete without this beautiful, essential reference."--Paola Bacchetta
African Roots Brazilian Rites
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Author : C. Sterling
language : en
Publisher: Springer
Release Date : 2012-09-06
African Roots Brazilian Rites written by C. Sterling and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-06 with Political Science categories.
This text explores how Afro-Brazilians define their Africanness through Candomblé and Quilombo models, and construct paradigms of blackness with influences from US-based perspectives, through the vectors of public rituals, carnival, drama, poetry, and hip hop.
Cosmopolitan Archaeologies
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Author : Lynn Meskell
language : en
Publisher: Duke University Press
Release Date : 2009-04-17
Cosmopolitan Archaeologies written by Lynn Meskell and has been published by Duke University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-17 with Social Science categories.
An important collection, Cosmopolitan Archaeologies delves into the politics of contemporary archaeology in an increasingly complex international environment. The contributors explore the implications of applying the cosmopolitan ideals of obligation to others and respect for cultural difference to archaeological practice, showing that those ethics increasingly demand the rethinking of research agendas. While cosmopolitan archaeologies must be practiced in contextually specific ways, what unites and defines them is archaeologists’ acceptance of responsibility for the repercussions of their projects, as well as their undertaking of heritage practices attentive to the concerns of the living communities with whom they work. These concerns may require archaeologists to address the impact of war, the political and economic depredations of past regimes, the livelihoods of those living near archaeological sites, or the incursions of transnational companies and institutions. The contributors describe various forms of cosmopolitan engagement involving sites that span the globe. They take up the links between conservation, natural heritage and ecology movements, and the ways that local heritage politics are constructed through international discourses and regulations. They are attentive to how communities near heritage sites are affected by archaeological fieldwork and findings, and to the complex interactions that local communities and national bodies have with international sponsors and universities, conservation agencies, development organizations, and NGOs. Whether discussing the toll of efforts to preserve biodiversity on South Africans living near Kruger National Park, the ways that UNESCO’s global heritage project universalizes the ethic of preservation, or the Open Declaration on Cultural Heritage at Risk that the Archaeological Institute of America sent to the U.S. government before the Iraq invasion, the contributors provide nuanced assessments of the ethical implications of the discursive production, consumption, and governing of other people’s pasts. Contributors. O. Hugo Benavides, Lisa Breglia, Denis Byrne, Chip Colwell-Chanthaphonh, Alfredo González-Ruibal, Ian Hodder, Ian Lilley, Jane Lydon, Lynn Meskell, Sandra Arnold Scham