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H Ros Cobayes


H Ros Cobayes
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Magnesium In The Central Nervous System


Magnesium In The Central Nervous System
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Author : Robert Vink
language : en
Publisher: University of Adelaide Press
Release Date : 2011

Magnesium In The Central Nervous System written by Robert Vink and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.


The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.



Auditory Pathway


Auditory Pathway
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Author : Josef Syka
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Auditory Pathway written by Josef Syka and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Since the last symposium on "Neuronal Mechanisms of Hearing" held in Prague in 1980 and published in the volume of the same name (J. Syka and L. Aitkin, Eds. , Plenum Press, 1981), remarkable progress has been achieved in the understanding of the auditory system. A variety of new ideas and new methods have emerged. This progress can be easily documented by comparing the volume based on the 1980 Symposium with the program for the 1987 Symposium. For example, there were 45 contributions to auditory physiology in each symposium but there were 27 contributions focusing on anatomy in 1987 as compared to 7 in 1980, and perhaps most telling, there were 12 contributions to the neurochemistry of the system in 1987 while there were only 3 in 1980. In terms of percentages of contributions, neuroanatomy rose from 13% to 32% and neurochemistry (or chemical anatomy) rose from 5% in 1980 to 14% in 1987. These increases in the numbers and proportions of anatomical and neurochemical contributions undoubtedly reflects the increasing availabil ity and rising expertise in the new neuroanatomica1 and biochemical techniques most notably, tract-tracing by exploitation of axonal transport or by intracellular micro-injection methods, and neurotransmitter identifi cation by use of immunocytochemistry or receptor-binding techniques. New ideas have emerged on the function of cochlear hair cells particularly in connection with olivococh1ear bundle stimulation and supported by findings of contractile proteins in outer hair cells.



Contact Dermatitis


Contact Dermatitis
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Author : Peter J. Frosch
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-07

Contact Dermatitis written by Peter J. Frosch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-07 with Medical categories.


It is an unusual event for a textbook covering such a national and international networks and the use of highly specialized field as contact dermatitis to be standardized methodology, a highly differentiated published in its fourth edition within a time period picture can now be painted; we know the major p- of 13 years. When the European and Environmental fessions at risk, as well as the influences of age and Contact Dermatitis Research Group was founded in various cofactors. This is a solid basis for preventive 1985,one of the major goals was to edit a textbook of measures. A new allergen, described in one center, high scientific standard written by renown experts can now be tested on a large scale in a short time and keep it regularly updated. The greatest danger period. If the data evaluation shows an unacceptably for a textbook is to become outdated – then it stays high rate of sensitization in the exposed population, on the bookshelf and is rarely consulted. The contin- regulatory measures will be undertaken to protect uous flow of new medicaments, the fascinating the consumer. A recent example is the “methyldib- improvements in diagnostic image analysis and ever- mo glutaronitrile story. ” changing operative procedures are the reasons for These and other issues of importance are covered considerable knowledge deficits in old textbooks, in depth in the newest edition of this textbook.



Osteoarthritis


Osteoarthritis
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Author : J.-Y. Reginster
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Osteoarthritis written by J.-Y. Reginster and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Musculoskeletal diseases are rapidly becoming a major health concern. The incidence of osteoarthritis, the most common arthritic disorder, is increasing steadily due to the graying of the world population. This disease is responsible of human life, a time in for significant morbidity, particularly in the second half which the quality of life is of primary importance. The aim of this publication is to bring to physicians and scientists a comprehensive overview of the field, from molecules to men. The direct costs related to osteoarthritis have been increasing steadily over the years and will soon be comparable to those of other major illnesses, such as cardiovascular diseases. This, of course, does not take into account all of the other costs related to the disease which often cannot be simply calculated in dollars and cents. There has been a great deal of renewed interest in osteoarthritis in the last few decades. This has been brought on by the need to improve our knowledge of all aspects of the disease, especially with regard to its etiopathogenesis and treatment. The most recent findings and developments on the structural, bio chemical, biomechanical and molecular changes observed in clinical and ex perimental osteoarthritis are presented in this book.



Genome Mapping And Genomics In Animal Associated Microbes


Genome Mapping And Genomics In Animal Associated Microbes
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Author : Vishvanath Nene
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-11-24

Genome Mapping And Genomics In Animal Associated Microbes written by Vishvanath Nene and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-24 with Science categories.


Achievements and progress in genome mapping and the genomics of microbes supersede by far those for higher plants and animals, in part due to their enormous economic implication but also smaller genome size. In the post-genomic era, whole genome sequences of animal-associated microbes are providing clues to depicting the genetic basis of the complex host-pathogen relationships and the evolution of parasitism; and to improving methods of controlling pathogens. This volume focuses on a globally important group of intracellular prokaryotic pathogens which affect livestock animals. These include Brucella, Mycobacterium, Anaplasma and Ehrlichia, as well as the protozoan pathogens Cryptosporidium and Theileria, for which genome sequence data is available. Insights from comparative genomics of the microbes described provide clues to the adaptation involved in host-microbe interactions, as well as resources potentially useful for application in future research and product development.



Bone Circulation And Vascularization In Normal And Pathological Conditions


Bone Circulation And Vascularization In Normal And Pathological Conditions
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Author : A. Schoutens
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bone Circulation And Vascularization In Normal And Pathological Conditions written by A. Schoutens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The Association Internationale de Recherche sur la Circulation Osseuse, A.R.C.O., was founded in London in December 1989 by a small group of doctors, surgeons and researchers in basic sciences who had been involved for many years in the study of bone circulation and its disorders. They had met several times in Toulouse, during the International Symposia on Bone Circulation held there since 1973 and they wished to carry their contacts further. In founding A.R.C.O., they established as their primary aims the encouragement and furtherance of research, organisation of meetings and promotion of knowledge on the subject. At the present time, the Association has over a hundred members from more than bone tissue twenty countries in Europe, America and Asia. All have the conviction that and its pathology can only be truly known and studied if one has an understanding of its vascular system and the way its circulation functions. This concept, apparently beyond question, has not yet been adopted by all physicians and scientists who are interested in bone. From time to time, one comes across teaching programmes on bone patho logy which make no mention of bone circulation.



Environmental Hygiene Ii


Environmental Hygiene Ii
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Author : Norbert H. Seemayer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Environmental Hygiene Ii written by Norbert H. Seemayer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Environmental Hygiene II deals with the evaluation of environmental pollutants and their relevance to human health. Main topics include mutagenic and carcinogenic activity of environmental chemicals, specific effects of heavy metals, special biological indicators for screening environmental contaminants and monitoring of indoor/outdoor air pollutants. Furthermore, assessment of exposure to environmental and occupational chemicals in man are presented as well as epidemiological studies on the health effects by environmental pollution, studies of inhalation toxicology and strategies and policy of environmental control.



Epigenetics Of Aging And Longevity


Epigenetics Of Aging And Longevity
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Author : Alexey Moskalev
language : en
Publisher: Academic Press
Release Date : 2017-11-17

Epigenetics Of Aging And Longevity written by Alexey Moskalev and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-17 with Medical categories.


Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan



Dictionary Of French And English English And French


Dictionary Of French And English English And French
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Author : John Bellows
language : en
Publisher:
Release Date : 1911

Dictionary Of French And English English And French written by John Bellows and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1911 with English language categories.




Microbic Dissociation


Microbic Dissociation
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Author : Philip Bardwell Hadley
language : en
Publisher:
Release Date : 1927

Microbic Dissociation written by Philip Bardwell Hadley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1927 with Autolysis categories.