La Cultura Cient Fico Tecnol Gica Nacional

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Translational Medicine

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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26

Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.

Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Crop Ecology Cultivation And Uses Of Cactus Pear

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Author : Food and Agriculture Organization of the United Nations
language : en
Publisher: Food & Agriculture Org.
Release Date : 2018-06-05

Crop Ecology Cultivation And Uses Of Cactus Pear written by Food and Agriculture Organization of the United Nations and has been published by Food & Agriculture Org. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-05 with Nature categories.

Cactus plants are precious natural resources that provide nutritious food for people and livestock, especially in dryland areas. Originally published in 1995, this extensively revised edition provides fresh insights into the cactus plant’s genetic resources, physiological traits, soil preferences and vulnerability to pests. It provides invaluable guidance on managing the resource to support food security and offers tips on how to exploit the plant’s culinary qualities.

Measuring Innovation A New Perspective

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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2010-05-25

Measuring Innovation A New Perspective written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-25 with categories.

Measuring Innovation is a major step towards evidence-based innovation policy making. It complements traditional “positioning”-type indicators with ones that show how innovation is, or could be, linked to policy.

The United Nations World Water Development Report 2017

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Author : WWAP
language : en
Publisher: UNESCO Publishing
Release Date : 2017-03-15

The United Nations World Water Development Report 2017 written by WWAP and has been published by UNESCO Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-15 with Education categories.

The United Nations World Water Assessment Programme (WWAP) is hosted and led by UNESCO. WWAP brings together the work of 31 UN-Water Members and 38 Partners to publish The United Nations World Water Development Report, (WWDR) series. The annual World Water Development Reports focus on strategic water issues. UN-Water Members and Partners, all experts in their respective fields, contribute the latest findings on a specific theme. The 2017 edition of the World Water Development Report focuses on 'Wastewater' and seeks to inform decision-makers, inside and outside the water community, about the importance of managing wastewater as an undervalued and sustainable source of water, energy, nutrients and other recoverable by-products, rather than something to be disposed of or a nuisance to be ignored. The report's title - Wastewater: The Untapped Resource - reflects the critical role that wastewater is poised to play in the context of a circular economy, whereby economic development is balanced with the protection of natural resources and environmental sustainability, and where a cleaner and more sustainable economy has a positive effect on the water quality. Improved wastewater management is not only critical to achieving the Sustainable Development Goal on clean water and sanitation (SDG 6), but also to other goals of the 2030 Agenda for Sustainable Development.

World Anthropologies

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Author : Gustavo Lins Ribeiro
language : en
Publisher: Routledge
Release Date : 2020-07-13

World Anthropologies written by Gustavo Lins Ribeiro and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-13 with Social Science categories.

Since its inception, anthropology's authority has been based on the assumption that it is a unified discipline emanating from the West. In an age of heightened globalization, anthropologists have failed to discuss consistently the current status of their practice and its mutations across the globe. World Anthropologies is the first book to provoke this conversation from various regions of the world in order to assess the diversity of relations between regional or national anthropologies and a contested, power-laden Western discourse. Can a planetary anthropology cope with both the 'provincial cosmopolitanism' of alternative anthropologies and the 'metropolitan provincialism' of hegemonic schools? How might the resulting 'world anthropologies' challenge the current panorama in which certain allegedly national anthropological traditions have more paradigmatic weight - and hence more power - than others? Critically examining the international dissemination of anthropology within and across national power fields, contributors address these questions and provide the outline for a veritable world anthropologies project.

The Study Of Teaching

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Author : Michael J. Dunkin
language : en
Publisher:
Release Date : 1982

The Study Of Teaching written by Michael J. Dunkin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Education categories.

O Quarto Paradigma

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Author : Tony Hey
language : pt
Publisher: Oficina de Textos
Release Date :

O Quarto Paradigma written by Tony Hey and has been published by Oficina de Textos this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.

Publicado em parceria com a Microsoft Research, este livro apresenta pela primeira vez as pesquisas para a formulação do chamado Quarto Paradigma - uma nova metodologia de desenvolver ciência, baseada no uso intensivo de dados e na utilização de computação avançada para interpretar essas informações e criar novo conhecimento. Ao avaliar os novos campos de colaboração entre tecnologia e ciência, esta obra procura apontar tendências, além de inspirar uma nova geração de cientistas.

World Report On Violence And Health

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Author : World Health Organization
language : en
Publisher:
Release Date : 2002

World Report On Violence And Health written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Adolescence categories.

This report is part of WHO's response to the 49th World Health Assembly held in 1996 which adopted a resolution declaring violence a major and growing public health problem across the world. It is aimed largely at researchers and practitioners including health care workers, social workers, educators and law enforcement officials.

Vicente Rojo

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Author : Federico Álvarez
language : en
Publisher: Rm
Release Date : 2015

Vicente Rojo written by Federico Álvarez and has been published by Rm this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Art categories.

Since his arrival in Mexico in the 1950s, Vicente Rojo (b. Barcelona, 1932) has been a multiple artist: painter, designer, editor; his work produces while frames the modern visibility in Mexico. The catalogue "Printed/painted" explores the tension and mutual understanding of the main activities of Rojo, as a painter and as a designer, which could be defined as a modernist creative tension.

Teaching Children To Think

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Author : Robert Fisher
language : en
Publisher: Nelson Thornes
Release Date : 2005

Teaching Children To Think written by Robert Fisher and has been published by Nelson Thornes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Education categories.

Discusses key areas including emotional intelligence, cognitive acceleration, and the use of ICT in teaching thinking.