Living Donor Liver Transplantation The Asian Perspective
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Living Donor Liver Transplantation
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Author : Chao-Long Chen
language : en
Publisher:
Release Date : 2003
Living Donor Liver Transplantation written by Chao-Long Chen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Living Donor Liver Transplantation
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Author :
language : en
Publisher:
Release Date : 2014
Living Donor Liver Transplantation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Living Donor Liver Transplantation
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Author : Chao-Long Chen
language : en
Publisher:
Release Date : 2003
Living Donor Liver Transplantation written by Chao-Long Chen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Living Donor Liver Transplantation 2nd Edition
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Author : Sheung Tat Fan
language : en
Publisher: World Scientific
Release Date : 2011-03-08
Living Donor Liver Transplantation 2nd Edition written by Sheung Tat Fan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-08 with Medical categories.
The book describes in detail the technical aspects of Living Donor Liver Transplantation (LDLT), the routine practice of the world renowned Liver Transplant Team at Hong Kong's Queen Mary Hospital, and our views on various issues of the operation. The thorough review on the history and technical procedures of LDLT and discussion on various aspects of the operation and its future perspectives will serve as a unique reference for surgeons, researchers, nurses, medical students, patients and laypersons seeking information on LDLT.This latest edition offers updated operative results from our center and the latest modifications of the technique. With contributions from a leading microvascular surgeon, a critical care clinician, a psychiatrist, and two anesthetists from the same liver transplant team, the LDLT experience at Queen Mary Hospital is depicted in an even greater extent.
Living Donor Liver Transplantation
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Author : Sheung Tat Fan
language : en
Publisher: World Scientific
Release Date : 2011
Living Donor Liver Transplantation written by Sheung Tat Fan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
The book describes in detail the technical aspects of Living Donor Liver Transplantation (LDLT), the routine practice of the world renowned Liver Transplant Team at Hong Kong's Queen Mary Hospital, and our views on various issues of the operation. The thorough review on the history and technical procedures of LDLT and discussion on various aspects of the operation and its future perspectives will serve as a unique reference for surgeons, researchers, nurses, medical students, patients and laypersons seeking information on LDLT. This latest edition offers updated operative results from our center and the latest modifications of the technique. With contributions from a leading microvascular surgeon, a critical care clinician, a psychiatrist, and two anesthetists from the same liver transplant team, the LDLT experience at Queen Mary Hospital is depicted in an even greater extent.
Living Donor Liver Transplantation Surgical Techniques And Innovations
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Author :
language : en
Publisher: Prous Science
Release Date : 2003
Living Donor Liver Transplantation Surgical Techniques And Innovations written by and has been published by Prous Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Donor Perspective Of Right Lob
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Author : See-Ching Chan
language : en
Publisher: Open Dissertation Press
Release Date : 2017-01-26
Donor Perspective Of Right Lob written by See-Ching Chan and has been published by Open Dissertation Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-26 with Medical categories.
This dissertation, "Donor Perspective of Right Lobe Adult-to-adult Live Donor Liver Transplantation" by See-ching, Chan, 陳詩正, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled Donor Perspective of Right Lobe Adult-to-Adult Live Donor Liver Transplantation submitted by See Ching CHAN for the Degree of Master of Surgery at the University of Hong Kong in August 2005 Donors of adult-to-adult live donor liver transplantation (ALDLT) undergo a very major surgical operation which carries a 0.5% mortality, 20% morbidity, and has unknown long-term consequences. Despite these caveats, ALDLT is now an accepted treatment modality and has saved the lives of thousands of patients with end-stage liver disease of various etiologies and small unresectable hepatocellular carcinoma. The rapid adoption of ALDLT is associated with the scarcity of deceased donor liver grafts. However, pure demand from the recipient should not progress to ALDLT. To a minimum, it is the potential donor's perception of the expected recipient outcomes and the donor costs which substantiates such voluntarism. Nonetheless, the potential donors are seldom trained to make such decisions. We as guardians are obligated to guide the potential donors and the potential recipients throughout the process. Conversance of contemporary donor and recipient outcomes is therefore mandatory. The ultimate aim of this thesis was to provide a synopsis of the endeavors toward the holistic care of the highest standard for donors of right lobe ALDLT. This was done through: 1) optimum donor workup, 2) accurate graft size requirement estimation, 3) safe donor right hepatectomy, 4) quantifying quality of life of donor, 5) documentation of long-term biological consequences of donor surgery, and 6) establishing standards for donor right hepatectomy. In a cohort of 399 potential donors for ALDLT, 32.1% (128/399) underwent donor operation. Dropouts because of incompatible blood group, positive hepatitis ii serology, and voluntary donor withdrawal were 52.6% (210/399). Only 11.6% (22/189) were determined unsuitable for psychological or anatomical reasons as revealed in the further workup. Careful and expeditious initial donor workup minimized wastage which was not related to blood group or serological reasons. Adequacy of graft size is a prerequisite for recipient survival. Based on the right lobe graft weight on the back table and the volumetric analysis of donor computed tomography, a formula of liver weight estimation by body weight and gender for the local population was derived: liver weight (g) = 218 + body weight (kg) x 12.3 + gender x 51 (female = 0, male = 1). The technicality of donor right hepatectomy contributes directly to the donor safety and recipient success. Based on donor computed tomography and operative data, preservation of segment 4b hepatic vein with substantial venous drainage into the middle hepatic vein for donors was validated as clinically important. Even though the liver has remarkable regenerative ability, right lobe donors operated over two and a half years or earlier had statistically significant decrease in the white cell count, and elevation of serum creatinine, alanine aminotransferase, aspartate aminotransferase, and bilirubin at follow-up. Using the Chinese (Hong Kong) version of the Medical Outcomes 36-Item Short-Form Survey and a condition-specific questionnaire, physical abilities of donors were temporarily compromised, while the psychological domains were not affected. Older d
Application Of Living Donor Liver Transplantation To Adult Recipients In Hong Kong
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Author : Chung-Mau Lo
language : en
Publisher:
Release Date : 2017-01-27
Application Of Living Donor Liver Transplantation To Adult Recipients In Hong Kong written by Chung-Mau Lo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-27 with categories.
This dissertation, "Application of Living Donor Liver Transplantation to Adult Recipients in Hong Kong" by Chung-mau, Lo, 盧寵茂, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: ABSTRACT of thesis entitled: "Application of living donor liver transplantation to adult recipients in Hong Kong" Submitted by Dr. Chung-Mau LO for the degree of Master of Surgery at the University of Hong Kong in July 1998 Despite the acceptance of organ transplantation from brain-dead donors in Hong Kong, the availability of cadaveric liver grafts is severely restricted by Chinese religious and cultural traditions. For 3 years since the initiation of the liver transplant program at Queen Mary Hospital in October 1991, only nine cadaveric grafts were available for transplantation and the liver donor rate in 1993 was 0.6 per million populations per year. With the application of living donor liver transplantation (LDLT) to pediatric patients, the disparity between the supply and demand for donor organs was in adult recipients. In particular, high-urgency candidates who required emergency transplantation had a pretransplantation mortality of nearly 100%. A review of the literature showed that the extension of LDLT to adults had not been made with success. The aim of this thesis is to develop a strategy to overcome the problem of organ shortage by evaluating the possible application of LDLT to adult recipients in Hong Kong. From July 1994, 5 adult patients underwent LDLT using a full left lobe graft. Four of the operations were performed as an emergency for high-urgency candidates. The donor-to-recipient body weight ratio ranged from 104% to 139%. Although the body weights and heights of all the donors were greater than those of the ncorresponding recipients, the weight of the left lobe graft amounted to only 31% to 54% of the recipient's expected liver weight. Two recipients developed early graft dysfunction and died. The other 3 recipients (60%) survived after a period of cholestasis. From May 1996 to January 1998, a new technique of liver transplantation using an extended right lobe graft from a living donor was applied to 9 high-urgency adult patients. The body weights of 5 donors were less than those of the corresponding recipients and the lowest donor-to-recipient body weight ratio was 62%. Nonetheless, the ratio of the graft weight to the recipient's expected liver weight (graft weight ratio) was more than 40% in all except one cases and 8 of 9 recipients (89%) survived with the original graft at a median follow-up of 16.5 months. The technique has overcome the problem of donor-to-recipient size match and extended the success of LDLT from children to adults of virtually all sizes. To establish the criteria for selecting the type of donor operation, a retrospective analysis of 25 LDLTs using 9 extended right lobe grafts and 16 left lobe or left lateral segment grafts was undertaken. For the donor, an extended right lobectomy carried a higher risk of transient postoperative liver dysfunction, a prolonged hospital stay, and possibly increased morbidity. For the recipient, on the other hand, when the graft weight ratio was 100% (p = 0.016, graft weight ratio 40%). An analysis of 49 consecutive high-urgency adult patients listed for emergency liver transplantation at Queen Mary Hospital betwe
Living Donor Liver Transplantation For Hepatocellular Carcinoma
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Author : Chih-Che Lin
language : en
Publisher:
Release Date : 2017
Living Donor Liver Transplantation For Hepatocellular Carcinoma written by Chih-Che Lin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Medicine categories.
Hepatocellular carcinoma (HCC) is a major worldwide health problem, which is expected to increase steadily due to different underlying liver diseases. Surgical treatment modalities including liver transplantation (LT) or liver resection (LR) are the mainstay options for early cases of HCC. Liver transplantation for well-selected cases provides excellent survival outcomes comparable to nonmalignant indications of LT. Living donor liver transplantation (LDLT) is an alternative option or even the sole one in the current era of organ shortage problem and in some Asian countries where deceased organ donation is markedly reduced due to various reasons. The adoption of LDLT for HCC treatment elicited many dynamic changes and debates to the dilemma of LT as a whole. In this chapter, we focus on different perspectives of LDLT for HCC, including selection criteria evolution, controversial topics, ethical considerations, operative highlights, and other points.
Overweight And Obesity In The Western Pacific Region An Equity Perspective
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Author : WHO Regional Office for the Western Pacific
language : en
Publisher: World Health Organization
Release Date : 2018-09-11
Overweight And Obesity In The Western Pacific Region An Equity Perspective written by WHO Regional Office for the Western Pacific and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-11 with Medical categories.
Overweight and obesity have become urgent global health issues in recent decades. Globally the number of overweight children under the age of 5 years has increased from 32 million in 2000 to 41 million in 2014 corresponding to an increase in prevalence from 5.0% to 6.1%. It is estimated that at the current pace by 2020 some 9% of all children under 5 years will be overweight. Furthermore an increase in adult obesity prevalence has been observed in all countries and globally the prevalence of obesity among adults has doubled from 1980 to 2014 from 5% to 11% for men and from 8% to 15% for women. Overweight and obesity were estimated to account for 3.4 million deaths annually and 93.6 million disability-adjusted life years (DALYs) 1 in 2010. The burden of overweight and obesity is inequitably distributed and affects some population groups and geographical areas more than others based on their social characteristics which are also inequitably distributed. Vulnerability to overweight and obesity might depend on for instance urban or rural residence socioeconomic status ethnicity or the geographical area where people live and their nutritional status in the first 1000 days of life. This report intends to assist policy-makers in the World Health Organization (WHO) Western Pacific Region by contributing to a better understanding of the unequal distribution of overweight and obesity in the Region and by providing policy options to address the social determinants of overweight and obesity. Identifying vulnerable population groups or areas can help policymakers programme managers and other actors to improve programme targeting and increase the effectiveness and improve the health and well-being of the most vulnerable.