Melatonina
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Melatonin
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Author : Hing-Sing Yu
language : en
Publisher: CRC Press
Release Date : 2020-10-28
Melatonin written by Hing-Sing Yu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Science categories.
Melatonin: Biosynthesis, Physiological Effects, and Clinical Applications provides a thorough review of recent advances in major areas of melatonin research. The book is arranged in a logical sequence, beginning with the history of melatonin and then proceeding to cover its biochemistry and secretion, physiological effects, and clinical significance. New findings and current concepts are emphasized, and a significant amount of previously unpublished data are included. The book will be an important reference for neurobiologists, cell biologists, ophthalmologists, endocrinologists, neuroendocrinologists, reproductive biologists, psychiatrists, and other researchers and clinicians interested in melatonin.
Melatonin In Plants Role In Plant Growth Development And Stress Response
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Author : Anket Sharma
language : en
Publisher: Springer Nature
Release Date :
Melatonin In Plants Role In Plant Growth Development And Stress Response written by Anket Sharma and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Antioxidant Effect Of Melatonin On Saccharomyces And Non Saccharomyces Wine Yeasts
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Author : Jennifer Vázquez González
language : en
Publisher:
Release Date : 2017
Antioxidant Effect Of Melatonin On Saccharomyces And Non Saccharomyces Wine Yeasts written by Jennifer Vázquez González and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
La melatonina (N-acetil-5 metoxytryptamine) que es sintetitza a partir de triptòfan, es forma durant la fermentació alcohòlica, no obstant el seu paper en el llevat és desconegut. Aquest estudi va utilitzar espècies de Saccharomyces i no Saccharomyces per avaluar els possibles efectes antioxidants de melatonina. Es va avaluar la resistència al H2O2, la producció d'espècies reactives d'oxigen, la peroxidació lipídica, l'activitat catalasa i a la composició lipídica (àcids grassos, fosfolípids i esterols) tant en llevats de Saccharomyces com no-Saccharomyces. A més, a S. cerevisiae es va avaluar el contingut de glutatió reduït i oxidat, es va quantificar la melatonina endògena i es va realitzar un assaig transcriptòmic. Els resultats van mostrar que els llevats que contenen àcids grassos insaturats com els àcids linoleic o linolènic són més tolerants a l'estrès oxidatiu. Per altra banda, la suplementació amb melatonina va facilitar que les cèl·lules fessin front a possibles estressos futurs. Tanmateix, quan les cèl·lules van ser sotmeses a estrès oxidatiu induït per H2O2, la melatonina va poder mitigar parcialment el dany cel·lular reduint la producció de ROS, la peroxidació de lípids i el glutatió oxidat a la vegada que augmentava el glutatió reduït i la viabilitat cel·lular. L̀anàlisi de transcriptòmica va demostrar que la melatonina és capaç de modular la resposta a l'estrès oxidatiu a nivell transcripcional. Els resultats demostren que la melatonina pot actuar com antioxidant tant en llevats Saccharomyces com en no-Saccharomyces.
Melatonin Metabolism In Yeast Cells During Alcoholic Fermentation
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Author : María de los Ángeles Morcillo Parra
language : en
Publisher:
Release Date : 2019
Melatonin Metabolism In Yeast Cells During Alcoholic Fermentation written by María de los Ángeles Morcillo Parra and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
La melatonina és una indolamina que és produïda pel llevat a partir de l'aminoàcid triptòfan durant la fermentació alcohòlica. En aquesta tesi, estudiem la producció de melatonina en most sintètic en diferents condicions ambientals i nutricionals pels llevats, així com l'efecte d'aquesta molècula bioactiva en la dinàmica de poblacions d'una fermentació. Com a resultats, observem que la detecció estava desfasada entre la producció intracel·lular, la qual va ocórrer durant la fase d'adaptació al medi i la secreció al medi extracel·lular durant la fase exponencial o estacionària. Així mateix, la presència de melatonina millorava el desenvolupament de la fermentació i augmentava la presència de llevats no-Saccharomyces a final de fermentació. A més, vam analitzar la interacció d'aquesta molècula amb proteïnes durant la fermentació. Els resultats van mostrar que la melatonina s'unia a enzims glicolítics en llevats que tenien una alta capacitat fermentativa, reforçant la idea que la melatonina podria actuar com una molècula senyal durant la fermentació alcohòlica. Finalment, es va optimitzar un nou mètode de detecció per fluorescència utilitzant una línia cel·lular que presenta el receptor humà de melatonina per a mostres procedents de begudes fermentades. Els resultats van mostrar que aquest nou mètode disminueix el límit de detecció i és una bona alternativa en comparació amb el mètode de detecció de melatonina basat en cromatografia. No obstant, es necessita una extracció de la mostra per a realitzar l'anàlisi de melatonina.
Melatonin And The Mammalian Pineal Gland
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Author : Josephine Arendt
language : en
Publisher: Springer Science & Business Media
Release Date : 1994-12-31
Melatonin And The Mammalian Pineal Gland written by Josephine Arendt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-12-31 with Science categories.
This volume provides the reader with an overview of an intriguing and interdisciplinary field of research. For the first time the mammalian pineal gland, its mode of action and its physiological effects are discussed in a comprehensive, single-authored work.
Melatonin In The Promotion Of Health Second Edition
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Author : Ronald Ross Watson
language : en
Publisher: CRC Press
Release Date : 2017-05-31
Melatonin In The Promotion Of Health Second Edition written by Ronald Ross Watson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-31 with Electronic book categories.
"This new edition presents information on how melatonin is synthesized and produced in the body as well as how this hormone affects several diseases. The book heavily focuses on prevention as well as treatment of various human disease states including behavior disorders, mental disorders, breast cancer, bone health, and gastrointestinal diseases. It covers the role of melatonin in the prevention of oxidative stress, mutagenesis, sun damage, ocular health, gut motility, and detoxification. It also presents mechanisms of melatonin action in humans including cell modulation, signaling mechanisms, protective effects, and melatonin receptors as well as its role as an antioxidant"--Provided by publisher.
Melatonin
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Author : Alejandro Romero Martínez
language : en
Publisher:
Release Date : 2021
Melatonin written by Alejandro Romero Martínez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Melatonin categories.
"The exponential influx of scientific research on melatonin is associated with a greater orientation towards the study of the systemic effects of melatonin and their derivatives, as well as their clinical implications. Proof of this fact is summarized in the present compilation, where melatonin is presented as a remarkable agent to counteract most of the physiopathological events that trigger several disorders. The book also collects evidence about melatonin's interactions with two high-affinity G protein-coupled receptors to provide new pharmacological targets for the treatment of cancer, neurological or endocrine conditions. The present review also includes detailed coverage of molecules with improved safety profiles and melatonin receptor agonists (such as ramelteon, tasimelteon, and agomelatine), and the latest findings on the role of melatonin in protecting plants from abiotic stress, improving their resistance to adverse conditions, regulating several environmental stresses including heat stress, as well as the clinical use of melatonin in the treatment of fertility-related problems and reproductive health. The multiplicity of actions of melatonin, including modulating immune responses and inflammation and maintaining mitochondrial integrity, make this indoleamine a valuable therapeutic agent in the treatment of neurodegeneration, polycystic ovary syndrome, brain ischemia and traumatic brain injury, fibromyalgia, optic neuritis and glaucoma, alone or in combination with other drugs. Melatonin easily crosses the blood-brain and placental barriers. In this sense, this book provides a complete review suggesting that melatonin supplementation should be considered as a potential disease-preventing agent, with the aim of extending pregnancy duration to improve clinical outcomes and prevent fetal brain damage for pregnancy pathologies, such as preeclampsia, intrauterine growth restriction and preterm birth. Within the last few decades, melatonin has emerged in clinical oncology as a naturally occurring bioactive molecule with substantial anticancer properties. In addition, this chronobiotic agent exerts oncostatic effects throughout all stages of tumor growth, from initial cell transformation to mitigation of malignant progression and metastasis. Its therapeutic applications in oral cancer, gastrointestinal pathologies and colorectal cancer are discussed, as well as its applications as an adjuvant for alleviating side-effects and improving the welfare of radio/chemotherapy-treated patients. In the final chapter, the authors summarize the indications for the development of new galenic formulations of melatonin. Thus, different melatonin formulations, such as intranasal solutions, sprays, microspheres, gels and liposomes would allow for the maintenance of endogenous active concentrations for a long time, avoiding poor oral bioavailability"--
Melatonina Il Sonnifero Naturale
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Author : Ray Sahelian
language : it
Publisher: Tecniche Nuove
Release Date : 1996
Melatonina Il Sonnifero Naturale written by Ray Sahelian and has been published by Tecniche Nuove this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
La Melatonina
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Author : Hasnain Walji
language : es
Publisher: Plaza & Janes Editories Sa
Release Date : 1996
La Melatonina written by Hasnain Walji and has been published by Plaza & Janes Editories Sa this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Anti-aging hormone categories.
Treatise On Pineal Gland And Melatonin
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Author : Chandana Haldar
language : en
Publisher: Science Publishers
Release Date : 2002
Treatise On Pineal Gland And Melatonin written by Chandana Haldar and has been published by Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
This text includes recent literature on pineal research on reproduction, melatonin rhythm, carbohydrate metabolism and immunity.