Minhas P Rolas
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Problems Of Cryobiology
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Author :
language : en
Publisher:
Release Date : 1994
Problems Of Cryobiology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.
Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Problems Of Cryobiology
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Author :
language : en
Publisher:
Release Date : 1994
Problems Of Cryobiology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.
Dicion Rio De Onomatopeias E Voc Bulos Expressivos
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Author : Wagner Azevedo
language : pt-BR
Publisher: Editora Moan
Release Date : 2022-12-12
Dicion Rio De Onomatopeias E Voc Bulos Expressivos written by Wagner Azevedo and has been published by Editora Moan this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-12 with Foreign Language Study categories.
Esta é a 2ª edição revista e ampliada do bem-sucedido Dicionário de Onomatopeias e Vocábulos Expressivos, resultado de uma pesquisa prazerosa nas letras da MPB, nas literaturas, poemas e nas histórias em quadrinhos. Esta obra está dividida em três partes: Primeira Parte, Segunda Parte e Adendo. A Primeira Parte reúne os vocábulos gerais que estão registrados nos dicionários convencionais como onomatopeia ou vocábulo expressivo, inclusive os que estão registrados como “prov.” (provavelmente) e “talvez” pelos autores e ainda os vocábulos onomatopaicos registrados como tal por autores de literaturas, livros diversos e letras da MPB. A Segunda Parte reúne os vocábulos que são muito parecidos com a onomatopeia ou com o vocábulo expressivo, mas não estão assinalados como tal nos dicionários convencionais, ou porque são de origem desconhecida ou porque são de origem estrangeira (no caso da onomatopeia, pois o vocábulo expressivo é somente da Língua Portuguesa). O Adendo apresenta vocábulos comuns que não são onomatopeias, entretanto, são usados como tal; e alguns caracteres usados especificamente nos gibis e histórias em quadrinhos.
Platelets And Their Factors
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Author : Franz von Bruchhausen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Platelets And Their Factors written by Franz von Bruchhausen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and perhaps safer antiplatelet drugs is one of the most active areas of investigation in both basic and clinical research. Platelets, especially human platelets, have also emerged as one of the major models for the study of inter- and intracellular signal transduction pathways. Many biochemists, cell biologists, pharmacologists, pathologists, hematologists, and cardiologists find platelets useful for studying processes such as adhesion, inside-out and outside-in signalling through the plasma membrane, channels, calcium homeostasis, protein kinases, the network of intracellular signal transduction cascades, and the release of vasoactive substances. The aim of the editors has been to compile chapters summarizing the current state-of-the-art information on the biochemistry, cell biology, pharmacology, and physiologic and pathophysiologic roles of human platelets. We hope that this volume represents the major aspects of current platelet research although it is perhaps inevitable that certain areas are covered less thoroughly than others. We would like to acknowledge the excellent help and support of the Springer-Verlag staff, in particular that of Ms. Doris Walker.
B Blia Do Pregador Pentecostal
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Author : Sociedade Bíblica do Brasil
language : pt-BR
Publisher: Sociedade Bíblica do Brasil
Release Date : 2017-03-02
B Blia Do Pregador Pentecostal written by Sociedade Bíblica do Brasil and has been published by Sociedade Bíblica do Brasil this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-02 with Bibles categories.
A Bíblia do Pregador Pentecostal reúne 1.002 sermões bíblicos associados ao texto bíblico, que servirão de auxílio e orientação para pregações voltadas aos mais diversos públicos e ocasiões. Os sermões, preparados pelo teólogo e pastor Erivaldo de Jesus, abordam cada um dos 66 livros da Bíblia, além de tratarem de temas para ministrar a Palavra de Deus em convenções de pastores, reuniões de obreiros, escolas bíblicas, reuniões para mulheres e festividades em geral da Igreja. Cada sermão é subdividido em variados tópicos e referências bíblicas acerca do tema abordado e possui os três elementos fundamentais do princípio da homilética, que é a arte de pregar: introdução, explanação e conclusão. A publicação oferece, ainda, um curso básico de Teologia, composto de 12 matérias teológicas, que dará uma pequena noção do que é Teologia e sua importância para o crescimento espiritual, intelectual e bíblico de todos os estudantes da Bíblia Sagrada.
My Sweet Orange Tree
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Author : José Mauro de Vasconcelos
language : en
Publisher: Pushkin Press
Release Date : 2018-01-04
My Sweet Orange Tree written by José Mauro de Vasconcelos and has been published by Pushkin Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-04 with Juvenile Fiction categories.
A worldwide classic of children's literature - a moving, life-affirming childhood story, finally available in English again Meet Zezé - Brazil's naughtiest and most loveable boy, his talent for mischief matched only by his great kindness. When he grows up he wants to be a 'poet with a bow-tie' but for now he entertains himself playing pranks on the residents of his family's poor Rio de Janeiro neighbourhood and inventing friends to play with. That is, until he meets a real friend, and his life begins to change... My Sweet Orange Tree is a worldwide classic of children's literature – never out of print in Brazil since it was first published in 1968, it has also been translated into an astonishing number of languages and won the hearts of millions of young readers from Korea to turkey, Poland to Thailand and in many other countries too. José Mauro de Vasconcelos (1920-84) was a Brazilian writer who worked as a sparring partner for boxers, a labourer on a banana farm, and a fisherman before he started writing at the age of 22. He is most famous for his autobiographical novel My Sweet Orange Tree, which tells the story of his own childhood in Rio de Janeiro.
Soil Degradation Restoration And Management In A Global Change Context
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-10-28
Soil Degradation Restoration And Management In A Global Change Context written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-28 with Science categories.
Soil Degradation, Restoration and Management in a Global Change Context, volume four in the Advances in Chemical Pollution, Environmental Management and Protection series, explores a wide breadth of emerging and state-of-the-art technologies and provides the best practices to manage soils affected by degradation. Soils are the base of life, thus a sustainable soil management is crucial in a context of global environmental change. Chapters in this new release include Soil degradation, processes, future treats and possible solutions, Agriculture and grazing environments, Abandoned and afforested lands, Environments affected by fire, Mining environments, Urban areas, and Lands affected by war. Covers a wide breadth of emerging and state-of-the-art technologies Includes contributions from an international board of authors Provides a comprehensive set of reviews Synthesizes all aspects involved in soil degradation
Plant Based Muscle Our Roadmap To Peak Performance On A Plant Based Diet
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Author : Robert Cheeke
language : en
Publisher: Plant-Based Muscle
Release Date : 2017-09-02
Plant Based Muscle Our Roadmap To Peak Performance On A Plant Based Diet written by Robert Cheeke and has been published by Plant-Based Muscle this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-02 with Health & Fitness categories.
Co-authored by plant-based athletes with more than 35 years' combined experience, Robert Cheeke and Vanessa Espinoza, Plant-Based Muscle is the most complete plant-based fitness book to be released since Shred It!. Sharing experiences from different perspectives, and different backgrounds in exercise and sports nutrition, this plant-based fitness duo brings you the information, motivation, and inspiration to take your plant-based athlete lifestyle to the next level. We wrote this book with you in mind. We want this to be an incredibly helpful manual, designed to provide you with the exact tools you need to achieve your health and fitness goals as a plant-based athlete. By athlete, we mean YOU. The inner athlete inside all of us is ready to come out, and this book will give you the confidence to unleash your best plant-based self. From start to finish, this book will provide you with the motivation, instruction, guidance, tips, recommendations, and resources to put you on the path to success. We've got you covered on everything from how to create a workout routine, to how to select quality foods and ingredients to prepare plant-based meals, to what to eat for improved athletic performance, to how to prevent and overcome injuries and setbacks. Here are some specific things that you can expect to learn from our 35+ years combined experience as plant-based athletes: Motivation to get you pumped up to achieve your goals Programs for muscle building Programs for fat burning Programs for fitness conditioning Samples of our actual meal plans and workouts Grocery shopping lists and tips Healthy plant-based meal plans Delicious plant-based recipes Meal preparation guidelines A detailed account of our nutrition and fitness philosophies Photo demonstrations of numerous exercises Strategies for effective outreach as plant-based athletes Techniques to prevent and overcome injuries
Os Da Minha Rua
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Author : Ondjaki
language : pt-BR
Publisher: Leya
Release Date : 2012-02-28
Os Da Minha Rua written by Ondjaki and has been published by Leya this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-28 with Fiction categories.
Há espaços que são sempre nossos. E quem os habita, habita também em nós. Falamos da nossa rua, desse lugar que nos acompanha pela vida. A rua como espaço de descoberta, alegria, tristeza e amizade. Os da Minha Rua tem nas suas páginas tudo isso.