Near Future B W Edition

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Novel Molecular Targets And Treatments For Gastroesophageal Cancer 2nd Edition

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Author : Bin Li
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-10

Novel Molecular Targets And Treatments For Gastroesophageal Cancer 2nd Edition written by Bin Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-10 with Medical categories.

Gastroesophageal cancer is among the most common malignant diseases worldwide and is associated with high mortality rates, leading to a substantial burden on public health and healthcare systems around the world. Chemotherapeutic drugs have achieved great success in the treatment of esophageal cancer; however, they also bring cytotoxicity to other organs and often have serious side effects. With the development of molecular diagnostics and biomarker discovery, the application of precision medicine has emerged to improve clinical outcomes. New antineoplastic therapy development is a timely topic in light of the recent development of precision medicine. New biotherapies aim to inhibit or regulate different targets, which are thought to be functionally selective or overexpressed in some types of tumors. In particular, progress has been made to understand the molecular biology of gastrointestinal cancer, resulting in the discovery of various molecular targets, such as KRAS, PD-1, PD-L1, EGFR, HER2 and VEGF. Moreover, anticancer agents, such as pembrolizumab, olaparib, trastuzumab, bevacizumab, either as single agents or in combination with conventional chemotherapy, have become part of the standard of care for treatment of advanced gastroesophageal cancer. This Research Topic provides a platform for recent studies on novel molecular targets and treatments for gastroesophageal cancer. Both Original Research articles and Reviews are welcome. Subjects may include but are not limited to: 1) Oncogenes and tumor suppressors; 2) Drug sensitivity/resistance; 3) Tumor metastasis and tumor microenvironment; 4) Biomarker discovery and epigenetic regulation.

Geography

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Author :
language : en
Publisher:
Release Date : 1975

Geography written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Geography categories.

Includes section "Reviews" and other bibliographical material.

Integrated Waste Biorefineries Achieving Sustainable Development Goals 2nd Edition

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Author : Mohammad Rehan
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-11

Integrated Waste Biorefineries Achieving Sustainable Development Goals 2nd Edition written by Mohammad Rehan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-11 with Technology & Engineering categories.

The United Nations' Sustainable Development Goals (SDGs) are designed to revolutionize societies to prepare for the future challenges. However, the practical implementation of such goals in many domains is are yet to be achieved despite of unique essence. Sustainable energy production (aligned with SDG 7), clean water and sanitation (aligned with SDG 6), sustainable waste services (aligned with SDG 11), and mitigating climate change impacts (aligned with SDG 13) have been the prime focus of SDGs. Moreover, much attention is being paid to research and development activities on waste prevention, reduction, recycling, and reuse to achieve responsible consumption and production (aligned with SDG 12). Waste biorefineries have emerged as a sustainable environmental management solution to achieve not only the aforementioned SDGs, but also to accomplish no poverty (aligned with SDG 1) and zero hunger (aligned with SDG 2) and to maintain well-being and good health aligned with (SDG 3) and decent work and economic growth (aligned with SDG 8) worldwide. This is true because integrated waste biorefineries can efficiently and sustainably produce fuels, heat, energy, power, and multiple value-added products and chemicals. It can further facilitate the transition from linear to circular economies and mitigate the major challenges faced, including environmental pollution, climate change, and adverse effects on public health. This Research Topic will focus on different types of waste biorefineries, current status, practical implications, optimization of waste-to-energy technologies, detailed life assessment studies, and future opportunities with a vision to achieve SDGs in the areas of sustainable energy generation, waste management, circular economies, and climate change mitigation. The editorial team of this special issue, consisting of world-renowned scientists including Highly Cited Researchers, welcomes submissions of original research articles, review articles, short communications, industrial and/or country/region case studies that covers the following enlisted topics: • Waste biorefineries (e.g., organic waste biorefinery, agricultural and forestry waste biorefinery, etc.) • Integration of different types of biorefineries • Sustainable development goals • Waste to energy technologies • Energy and resource recovery from biomass and other waste • Renewable and sustainable energy systems • Biomass and waste supply chain • Sustainable waste management systems • Mitigation of environmental pollution and climate change • Life cycle assessment • Sustainable circular and bio-based economies.

International Arms Control

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Author : Coit D. Blacker
language : en
Publisher: Stanford University Press
Release Date : 1984

International Arms Control written by Coit D. Blacker and has been published by Stanford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Political Science categories.

Completely revised and updated, this is an exhaustive analysis of national and international arms control: its history, philosophy, achievements and future prospects as well as its political, military and economic ramifications. Includes the complete text of the SALT II treaty and texts of major arms control agreements. ISBN 0-8047-1211-5 : $45.00; ISBN 0-8047-1212-0 (pbk.) : $16.95.

The Electrical Engineering Handbook Second Edition

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Author : Richard C. Dorf
language : en
Publisher: CRC Press
Release Date : 1997-09-26

The Electrical Engineering Handbook Second Edition written by Richard C. Dorf and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-09-26 with Technology & Engineering categories.

In 1993, the first edition of The Electrical Engineering Handbook set a new standard for breadth and depth of coverage in an engineering reference work. Now, this classic has been substantially revised and updated to include the latest information on all the important topics in electrical engineering today. Every electrical engineer should have an opportunity to expand his expertise with this definitive guide. In a single volume, this handbook provides a complete reference to answer the questions encountered by practicing engineers in industry, government, or academia. This well-organized book is divided into 12 major sections that encompass the entire field of electrical engineering, including circuits, signal processing, electronics, electromagnetics, electrical effects and devices, and energy, and the emerging trends in the fields of communications, digital devices, computer engineering, systems, and biomedical engineering. A compendium of physical, chemical, material, and mathematical data completes this comprehensive resource. Every major topic is thoroughly covered and every important concept is defined, described, and illustrated. Conceptually challenging but carefully explained articles are equally valuable to the practicing engineer, researchers, and students. A distinguished advisory board and contributors including many of the leading authors, professors, and researchers in the field today assist noted author and professor Richard Dorf in offering complete coverage of this rapidly expanding field. No other single volume available today offers this combination of broad coverage and depth of exploration of the topics. The Electrical Engineering Handbook will be an invaluable resource for electrical engineers for years to come.

The Future Of Philology

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Author : Hannes Bajohr
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2014-06-19

The Future Of Philology written by Hannes Bajohr and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-19 with Literary Criticism categories.

Philology, master science of the nineteenth century, has changed so radically over the course of the twentieth century that it is hardly recognizable in the twenty-first. Its scope has been transformed, its methodology contested, and its legitimacy called into doubt. Does it still make sense to speak institutionally and epistemologically of ‘philology’? Does this venerable title continue to signify a truly coherent field, and not a multitude of scattered currents and competing genealogies, differing national characteristics, and inconsistent methodologies? This volume collects answers by a range of young philologists, given at the 11th Annual Columbia University German Graduate Student Conference. They show that philology, in its practices and theories, continues to be the fundament of the ever-expanding field of literature and language studies – and that a discipline whose very core is the care for the text wields competencies that are indispensable for neighboring fields. In conversation with Brecht and George, Hamann and Rilke, Nietzsche and Heidegger, these essays confront questions of materiality, epistemology, and ontology that define, as Sheldon Pollock put it, the “fate of a soft science in a hard world.”

Science And Technology Of Terrorism And Counterterrorism Second Edition

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Author : Mark A. Prelas
language : en
Publisher: CRC Press
Release Date : 2010-08-10

Science And Technology Of Terrorism And Counterterrorism Second Edition written by Mark A. Prelas and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-10 with Social Science categories.

Traditionally, resources on terrorism and counterterrorism tend to focus on the social, behavioral, and legal aspects of the subject, with minimal emphasis on the scientific and technological aspects. Taking into account these practical considerations, the second edition of Science and Technology of Terrorism and Counterterrorism discusses the nature of terrorism and the materials used by terrorists. It describes how intelligence professionals and law enforcement personnel can detect and destroy these materials, and how they can deal with terrorist groups. This volume begins by introducing the shift in analysis of terrorist attacks after September 11, 2001 and summarizes selected case studies. It discusses the origin and nature of terrorism and the factors involved in diplomacy. Covering a broad range of topics, the book examines: Aerosol dispersion of toxic materials Bioterrorism and the manufacture, detection, and delivery of biological agents Agricultural terrorism Nuclear terrorism and nuclear weapons systems, threats, and safeguards Chemical terrorism, including manufacture, detection, delivery, and decontamination Cyber-terrorism Personal protective equipment The role of government at federal, state, and local levels The role of international agencies and their resources, capabilities, and responsibilities The National Infrastructure Protection Plan As terrorist activities increase globally, it is critical that those charged with protecting the public understand the myriad of ways in which terrorists operate. While we cannot predict where, when, and how terrorists will strike, our vigilance in staying abreast of the terrorist threat is the only way to have a fighting chance against those who seek to destroy our world.

The Precipice

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Author : Toby Ord
language : en
Publisher: Hachette UK
Release Date : 2020-03-24

The Precipice written by Toby Ord and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-24 with Philosophy categories.

This urgent and eye-opening book makes the case that protecting humanity's future is the central challenge of our time. If all goes well, human history is just beginning. Our species could survive for billions of years - enough time to end disease, poverty, and injustice, and to flourish in ways unimaginable today. But this vast future is at risk. With the advent of nuclear weapons, humanity entered a new age, where we face existential catastrophes - those from which we could never come back. Since then, these dangers have only multiplied, from climate change to engineered pathogens and artificial intelligence. If we do not act fast to reach a place of safety, it will soon be too late. Drawing on over a decade of research, The Precipice explores the cutting-edge science behind the risks we face. It puts them in the context of the greater story of humanity: showing how ending these risks is among the most pressing moral issues of our time. And it points the way forward, to the actions and strategies that can safeguard humanity. An Oxford philosopher committed to putting ideas into action, Toby Ord has advised the US National Intelligence Council, the UK Prime Minister's Office, and the World Bank on the biggest questions facing humanity. In The Precipice, he offers a startling reassessment of human history, the future we are failing to protect, and the steps we must take to ensure that our generation is not the last. "A book that seems made for the present moment." —New Yorker

An Atlas Of Operative Laparoscopy And Hysteroscopy Second Edition

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Author : Jacques Donnez
language : en
Publisher: CRC Press
Release Date : 2001-05-15

An Atlas Of Operative Laparoscopy And Hysteroscopy Second Edition written by Jacques Donnez and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-15 with Medical categories.

Since its introduction in the 1980s, the use of endoscopic surgery in gynecology has grown tremendously, its equipment improved, and methods refined. Today it is clear that the future of gynecologic surgery lies in the realm of minimally invasive techniques. An Atlas of Operative Laparoscopy and Hysteroscopy, Second Edition is not just a how-to-do-the-surgery book, but also a guide to the pathogenesis, pathophysiology, and epidemiology of the urogynecological area. Thoroughly updated to reflect advances in methods and technology, the book covers established techniques such as laparoscopic tubal anastomosis, endometrial ablation, and ovarian surgery, to cite just a few. It pays special attention to emerging procedures and technologies, including the use of robotics and the treatment of carcinoma. Of particular importance is the section on complications, which shows you how to recognize and avoid potential pitfalls. With more than 850 illustrations, most in full color, An Atlas of Operative Laparoscopy and Hysteroscopy, Second Edition is informative and thorough. As a reference, as a text, and as a surgical manual, it provides the grounding in current and emerging surgical techniques you need to stay at the top of your field.

Advances In Design And Specification Languages For Embedded Systems

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Author : Sorin Alexander Huss
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-19

Advances In Design And Specification Languages For Embedded Systems written by Sorin Alexander Huss and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-19 with Technology & Engineering categories.

This book is the latest contribution to the Chip Design Languages series and it consists of selected papers presented at the Forum on Specifications and Design Languages (FDL'06), in September 2006. The book represents the state-of-the-art in research and practice, and it identifies new research directions. It highlights the role of specification and modelling languages, and presents practical experiences with specification and modelling languages.