O Clube Dos Pequenos Milion Rios
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Child Of The Dark
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Author : Carolina Maria de Jesus
language : en
Publisher: Signet Classic
Release Date : 2003
Child Of The Dark written by Carolina Maria de Jesus and has been published by Signet Classic this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Fiction categories.
An uneducated Black woman exposes the squalid living conditions and savage human relationships that she experienced in a Brazilian slum.
The Power Of Habit
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Author : Charles Duhigg
language : en
Publisher: Random House
Release Date : 2012-02-28
The Power Of Habit written by Charles Duhigg and has been published by Random House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-28 with Business & Economics categories.
NEW YORK TIMES BESTSELLER • This instant classic explores how we can change our lives by changing our habits. NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The Wall Street Journal • Financial Times In The Power of Habit, award-winning business reporter Charles Duhigg takes us to the thrilling edge of scientific discoveries that explain why habits exist and how they can be changed. Distilling vast amounts of information into engrossing narratives that take us from the boardrooms of Procter & Gamble to the sidelines of the NFL to the front lines of the civil rights movement, Duhigg presents a whole new understanding of human nature and its potential. At its core, The Power of Habit contains an exhilarating argument: The key to exercising regularly, losing weight, being more productive, and achieving success is understanding how habits work. As Duhigg shows, by harnessing this new science, we can transform our businesses, our communities, and our lives. With a new Afterword by the author “Sharp, provocative, and useful.”—Jim Collins “Few [books] become essential manuals for business and living. The Power of Habit is an exception. Charles Duhigg not only explains how habits are formed but how to kick bad ones and hang on to the good.”—Financial Times “A flat-out great read.”—David Allen, bestselling author of Getting Things Done: The Art of Stress-Free Productivity “You’ll never look at yourself, your organization, or your world quite the same way.”—Daniel H. Pink, bestselling author of Drive and A Whole New Mind “Entertaining . . . enjoyable . . . fascinating . . . a serious look at the science of habit formation and change.”—The New York Times Book Review
The Southern Book Club S Guide To Slaying Vampires
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Author : Grady Hendrix
language : en
Publisher: Quirk Books
Release Date : 2020-04-07
The Southern Book Club S Guide To Slaying Vampires written by Grady Hendrix and has been published by Quirk Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-07 with Fiction categories.
“This funny and fresh take on a classic tale manages to comment on gender roles, racial disparities, and white privilege all while creeping me all the way out. So good.”—Zakiya Dalila Harris, author of The Other Black Girl Steel Magnolias meets Dracula in this New York Times best-selling horror novel about a women's book club that must do battle with a mysterious newcomer to their small Southern town. Bonus features: • Reading group guide for book clubs • Hand-drawn map of Mt. Pleasant • Annotated true-crime reading list by Grady Hendrix • And more! Patricia Campbell’s life has never felt smaller. Her husband is a workaholic, her teenage kids have their own lives, her senile mother-in-law needs constant care, and she’s always a step behind on her endless to-do list. The only thing keeping her sane is her book club, a close-knit group of Charleston women united by their love of true crime. At these meetings they’re as likely to talk about the Manson family as they are about their own families. One evening after book club, Patricia is viciously attacked by an elderly neighbor, bringing the neighbor's handsome nephew, James Harris, into her life. James is well traveled and well read, and he makes Patricia feel things she hasn’t felt in years. But when children on the other side of town go missing, their deaths written off by local police, Patricia has reason to believe James Harris is more of a Bundy than a Brad Pitt. The real problem? James is a monster of a different kind—and Patricia has already invited him in. Little by little, James will insinuate himself into Patricia’s life and try to take everything she took for granted—including the book club—but she won’t surrender without a fight in this blood-soaked tale of neighborly kindness gone wrong.
Science Education And Citizenship
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Author : S. Terzian
language : en
Publisher: Springer
Release Date : 2012-12-28
Science Education And Citizenship written by S. Terzian and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-28 with History categories.
Science fairs, clubs, and talent searches are familiar fixtures in American education, yet little is known about why they began and grew in popularity. In Science Education and Citizenship, Sevan G. Terzian traces the civic purposes of these extracurricular programs for youth over four decades in the early to mid-twentieth century. He argues that Americans' mobilization for World War Two reoriented these educational activities from scientific literacy to national defense a shift that persisted in the ensuing atomic age and has left a lasting legacy in American science education.
Placar Magazine
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Author :
language : pt
Publisher:
Release Date : 1981-04-03
Placar Magazine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-04-03 with categories.
PLACAR: a maior revista brasileira de futebol. Notícias, perfis, entrevistas, fotos exclusivas.
From My Window
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Author :
language : en
Publisher:
Release Date : 2020-04-15
From My Window written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-15 with categories.
What do you see from your window? This #OwnVoices picture book from Brazil offers a firsthand view of what children growing up in the favelas of Rio de Janeiro see every day. A vibrant and diverse celebration of urban community living, brought to life by unique, colorful illustrations that juxtapose brick buildings with lush jungle plants.
Wikinomics
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Author : Anthony D. Williams
language : en
Publisher: Atlantic Books Ltd
Release Date : 2011-03-01
Wikinomics written by Anthony D. Williams and has been published by Atlantic Books Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-01 with Business & Economics categories.
An International Bestseller. An Economist Book of the Year. A Financial Times Book of the Year. Shortlisted for the Financial Times Business Book of the Year. Wikinomics shows how businesses can collaborate creatively with their customers to succeed in the age of Wikipedia, YouTube and Linux: 'The Number 1 must-read... A breathtaking piece of work.' Tom Peters. The knowledge, resources and computing power of billions of people are self-organizing into a massive, new collective force. Interconnected and orchestrated via blogs, wikis, chat rooms, peer-to-peer networks, and personal broadcasting, the web is being reinvented to provide the first global platform for collaboration in history.
All This Time
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Author : Mikki Daughtry
language : en
Publisher: Simon and Schuster
Release Date : 2020-09-29
All This Time written by Mikki Daughtry and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-29 with Young Adult Fiction categories.
From the team behind #1 New York Times bestseller Five Feet Apart comes a gripping new romance that asks: Can you find true love after losing everything? Kyle and Kimberly have been the perfect couple all through high school, but when Kimberly breaks up with him on the night of their graduation party, Kyle’s entire world upends—literally. Their car crashes and when he awakes, he has a brain injury. Kimberly is dead. And no one in his life could possibly understand. Until Marley. Marley is suffering from her own loss, a loss she thinks was her fault. And when their paths cross, Kyle sees in her all the unspoken things he’s feeling. As Kyle and Marley work to heal each other’s wounds, their feelings for each other grow stronger. But Kyle can’t shake the sense that he’s headed for another crashing moment that will blow up his life as soon as he’s started to put it back together. And he’s right. This book includes bonus content.
Conceitos Chave Em Sociologia Da Inf Ncia Perspetivas Globais Key Concepts On Sociology Of Childhood Global Perspectives
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Author : Catarina Tomás
language : pt
Publisher: UMinho Editora
Release Date : 2021-12-13
Conceitos Chave Em Sociologia Da Inf Ncia Perspetivas Globais Key Concepts On Sociology Of Childhood Global Perspectives written by Catarina Tomás and has been published by UMinho Editora this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-13 with Social Science categories.
Esta obra pretende ocupar um espaço ainda em aberto na área da Sociologia da Infância reunindo os contributos de 55 autores/as, nacional e internacionalmente reconhecidos/as, oriundos de geografias diversificadas, numa análise crítica sobre questões, temáticas e desafios que se colocam hoje na investigação em torno da infância e da(s) criança(s). O objetivo é reunir, num único volume, um conjunto significativo de reflexões científicas sobre conceitos centrais da investigação contemporânea na área, em português e em inglês, para desta forma possibilitar uma maior partilha e divulgação do conhecimento que se vai construindo a nível mundial. This book intends to fill a gap still open in the scientific area of Sociology of Childhood. It brings togheher the contributions of 55 authors, nationally and internationally recognized, from diverse geographies, in a renewed critical analysis on issues, themes and challenges currently placed in research on childhood and on the child(ren). The main goal is to share in a single volume a significant set of scientific reflections on key concepts of contemporary research in the area, in Portuguese and English, aiming to reach wider audiences around the globe.