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O Nordeste E A Pol Tica


O Nordeste E A Pol Tica
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Translational Medicine


Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26

Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.


Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.



Water Pricing And Public Private Partnership


Water Pricing And Public Private Partnership
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Author : Asit K. Biswas
language : en
Publisher: Routledge
Release Date : 2014-04-10

Water Pricing And Public Private Partnership written by Asit K. Biswas and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-10 with Science categories.


There is no question that water pricing and public-private partnership can improve water management practices in the future. However, this concept is neither the cure-all many proponents argue, nor the disaster its opponents forecast. Providing a comprehensive and objective assessment of what does and does not work, where, why and under what circumstances, this informative collection assesses the social, economic, equity and institutional implications. This cohesive set of carefully selected essays, the result of The Third World Centre for Water Management and the Inter-American Development Bank's decision to objectively and critically assess the experiences in these areas, transcends the current dogmatic debate on these complex issues. Providing an in-depth analysis and assessment of the main issues and constraints of water pricing, private sector participation and their affect on water supply, the collection draws on illustrative case studies from Argentina, Brazil, the USA and Western European countries amongst others. This is a special issue of the Journal of Water Resource Development.



Veja


Veja
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Author :
language : pt-BR
Publisher:
Release Date : 1987

Veja written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Brazil categories.




Estudos Pol Ticos E Sociais


Estudos Pol Ticos E Sociais
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Author :
language : pt-BR
Publisher:
Release Date : 1970

Estudos Pol Ticos E Sociais written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Political science categories.




Angola


Angola
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Author : World Bank
language : en
Publisher: World Bank Publications
Release Date : 2007-01-01

Angola written by World Bank and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-01 with Technology & Engineering categories.


Once one of the world's largest staple food producers, Angola is now known as a major oil exporter - the second largest producer in sub-Saharan Africa. Angola is also the world's fourth largest producer of rough diamonds in terms of value, with the potential to become one of the leading global diamond producers. In addition to oil and diamonds, the country is well endowed with agricultural resources which remain mostly untapped. However, despite the country's significant natural wealth, a prolonged civil war, the rapid development of the oil sector, and the policies pursued after Independence in 1975 have left the Angolan economy in a unique situation, characterized by very uneven indicators of development. The Angolan economy is now experiencing massive oil windfall gains that are expected to last throughout the next decade. Since oil rents are to a large part concentrated in the public sector, the question of how the oil revenue should be spent and distributed across present and future generations becomes key to any economic development strategy. This study identifies six core areas where a strategic approach for the development of a broad-based growth strategy is required: (i) the incomplete transition to a market economy; (ii) macroeconomic management; (iii) governance and transparency in the management of the mineral wealth; (iv) the business environment; (v) agriculture; and (vi) public service delivery to the poor.



Genetic Enhancement In Major Food Legumes


Genetic Enhancement In Major Food Legumes
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Author : Kul Bhushan Saxena
language : en
Publisher: Springer Nature
Release Date : 2021-09-28

Genetic Enhancement In Major Food Legumes written by Kul Bhushan Saxena and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-28 with Science categories.


The protein molecule is the basic building block of every living entity. Its deficiency leads to restricted growth and development of individuals. Globally, such malnutrition is on the rise due to various reasons such as rapid population growth, stagnation of productivity, and ever-rising costs. Millions of people, especially in developing and under-developed countries, suffer from protein malnutrition and the only possible solution is to encourage farmers to grow high-protein food legume crops in their fields for domestic consumption. This, however, could be possible if farmers are provided with new cultivars with high yield, and resistance to major insects, diseases, and key abiotic stresses. The major food legume crops are chickpea, cowpea, common bean, groundnut, lentil, pigeonpea, and soybean. Predominantly, the legume crops are grown under a subsistence level and, therefore, in comparison to cereals and horticultural crops their productivity is low and highly variable. The crop breeders around the globe are engaged in breeding suitable cultivars for harsh and changing environments but success has been limited and not up to needs. With the recent development of new technologies in plant sciences, efforts are being made to help under-privileged farmers through breeding new cultivars which will produce more protein per unit of land area. In this book, the contributors analyze the constraints, review new technologies, and propose a future course of crop breeding programs in seven cold and warm season legume crops.



6th International Conference On The Conservation Of Earthen Architecture


6th International Conference On The Conservation Of Earthen Architecture
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Author : The Getty Conservation Institute
language : en
Publisher: Getty Publications
Release Date : 1991-02-28

6th International Conference On The Conservation Of Earthen Architecture written by The Getty Conservation Institute and has been published by Getty Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-02-28 with Art categories.


On October 14-19, 1990, the 6th International Conference on the Conservation of Earthen Architecture was held in Las Cruces, New Mexico. Sponsored by the GCI, the Museum of New Mexico State Monuments, ICCROM, CRATerre-EAG, and the National Park Service, under the aegis of US/ICOMOS, the event was organized to promote the exchange of ideas, techniques, and research findings on the conservation of earthen architecture. Presentations at the conference covered a diversity of subjects, including the historic traditions of earthen architecture, conservation and restoration, site preservation, studies in consolidation and seismic mitigation, and examinations of moisture problems, clay chemistry, and microstructures. In discussions that focused on the future, the application of modern technologies and materials to site conservation was urged, as was using scientific knowledge of existing structures in the creation of new, low-cost, earthen architecture housing.



The New Peasantries


The New Peasantries
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Author : Jan Douwe van der Ploeg
language : en
Publisher: Routledge
Release Date : 2018-06-13

The New Peasantries written by Jan Douwe van der Ploeg and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-13 with Social Science categories.


When first published in 2008, The New Peasantries revolutionized our ways of thinking of what constitutes the peasantry and repeasantization. It showed how a new era of empire and globalization was creating new forms of peasantry. This new edition is thoroughly revised, with a reorganization of chapters and several new chapters added. It includes a new chapter on China, based on the author's extensive fieldwork there, and much more information on Brazil. It integrates and critically reviews the many publications on peasants, peasantries and peasant modes of agricultural production published in recent years. The theoretical discussion is enriched with more attention to the seminal work of Chayanov. Greater attention is also paid to the construction of new markets – a theme that will remain a major issue in the coming decade. It combines and integrates different bodies of literature: the rich traditions of peasant studies, development and rural sociology, neo-institutional economics and debates on empire and globalization. The original book has been used in several international postgraduate courses. The experience and feedback thus obtained has been used to simplify the structure of the book and make it more accessible as a textbook for students.



Silvopastoral Systems In Southern South America


Silvopastoral Systems In Southern South America
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Author : Pablo Luis Peri
language : en
Publisher: Springer
Release Date : 2016-03-02

Silvopastoral Systems In Southern South America written by Pablo Luis Peri and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-02 with Technology & Engineering categories.


This multi-authored volume contains peer-reviewed chapters from leading researchers and professionals in silvopastoral systems topic in Southern South America (Argentina, Chile and South Brazil). It is a compendium of original research articles, case studies, and regional overviews and summarizes the current state of knowledge on different components and aspects (pasture production, animal production, trees production, carbon sequestration, conservation) of silvopatoral systems in native forests and tree plantations. The main hypothesis of the book is that farmers have integrated tree and pasture/grassland species in their land use systems to reach higher production per unit of land area, risk avoidance, product diversification, and sustainability. These production systems also impact positively in main ecosystem processes. Management of these productive systems, Policy and Socioeconomic Aspects provide great opportunities and challenges for farmers and policy makers in our region. The book is unique on this subject in Southern South America and constitutes a valuable reference material for graduate students, professors, scientists and extensionists who work with silvopastoral systems.



Brasil A Ucareiro


Brasil A Ucareiro
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Author :
language : pt-BR
Publisher:
Release Date : 1942

Brasil A Ucareiro written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1942 with Alcohol categories.