Peixe El Trico 01
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Taxonomic Revision Of Cuphea Sect Euandra Subsect Oidemation Lythraceae
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Author : Shirley A. Graham
language : en
Publisher:
Release Date : 2013
Taxonomic Revision Of Cuphea Sect Euandra Subsect Oidemation Lythraceae written by Shirley A. Graham and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Cuphea categories.
Biology Of Semiarid Tropical Fish
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Author : José Rosa Gomes
language : en
Publisher: Nova Science Publishers
Release Date : 2014
Biology Of Semiarid Tropical Fish written by José Rosa Gomes and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Arid regions categories.
Brazil is home to equatorial, tropical, semi-arid, highland tropical, and subtropical climatic regions. The semiarid region of Northeastern Brazil, considered an area of drought polygon, has distinctive scrub vegetation referred to as Caatinga that covers over 10% of the Brazilian territory with approximately twenty million inhabitants. The Caatinga is considered one of the 37 Wilderness Areas of the World, and it plays an important role in the maintenance of regional macro-ecological processes, as well as indirectly supporting regions with biodiversity and endemism. The Brazilian semiarid region is also home to Neotropical fish species that occur in diversified aquatic ecosystems, exhibiting different strategies to survive and reproduce. In this scenario of fantastic diversity there exists an intensive and yet insufficiently known interaction of environmental factors and fish communities. To fully understand this it is necessary to know the details about how it works. For completed book description please visit our website at the link below.
Asylums
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Author : Erving Goffman
language : en
Publisher: Routledge
Release Date : 2017-09-08
Asylums written by Erving Goffman and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-08 with Social Science categories.
A total institution is defined by Goffman as a place of residence and work where a large number of like-situated, individuals, cut off from the wider society for an appreciable period of time, together lead an enclosed, formally administered round of life. Prisons serve as a clear example, providing we appreciate that what is prison-like about prisons is found in institutions whose members have broken no laws. This volume deals with total institutions in general and, mental hospitals, in particular. The main focus is, on the world of the inmate, not the world of the staff. A chief concern is to develop a sociological version of the structure of the self. Each of the essays in this book were intended to focus on the same issue--the inmate's situation in an institutional context. Each chapter approaches the central issue from a different vantage point, each introduction drawing upon a different source in sociology and having little direct relation to the other chapters. This method of presenting material may be irksome, but it allows the reader to pursue the main theme of each paper analytically and comparatively past the point that would be allowable in chapters of an integrated book. If sociological concepts are to be treated with affection, each must be traced back to where it best applies, followed from there wherever it seems to lead, and pressed to disclose the rest of its family.
Age And Gender Considerations In Psychiatric Diagnosis
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Author : William E. Narrow
language : en
Publisher: American Psychiatric Pub
Release Date : 2008-05-20
Age And Gender Considerations In Psychiatric Diagnosis written by William E. Narrow and has been published by American Psychiatric Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-20 with Medical categories.
Written to help identify major gaps in our knowledge of how gender and age affect psychiatric diagnoses and to stimulate much-needed research to fill these gaps, Age and Gender Considerations in Psychiatric Diagnosis serves as both a valuable short-term source for the DSM-V Task Force and its disorder-specific workgroups, and a long-term guide for future studies that will contribute to revised psychiatric classifications in these three areas. Here, 47 experts present findings in three areas of psychiatric research that historically have been neglected but rightfully have received increasing attention in recent years and thus are worthy of investigation into their clinical features, etiology, and course: 1. Significant gender differences in prevalence, symptom profiles, and risk factors for mental disorders, including neurodevelopmental, neurophysiological, and environmental factors for men and women that cut across diagnostic categories-for example, the critical importance of gender in how psychiatric illness develops and presents; DSM's approach to gender to date; and relevant research findings and gaps in the epidemiology, etiology, and pathophysiology of disorders and the gender-related expression of psychopathology, including the controversial and complex question of whether DSM should have different diagnostic criteria for men and women. 2. Mental disorders in infancy and early childhood, including diagnosis and measurement of psychopathology; PTSD and social and cognitive factors related to the experience of stress; reactive attachment disorder (unique in part because of its specificity to early childhood); mood and anxiety disorders and difficulties in diagnosis; sleep disorders, including two new disorders, Night-Waking Dysomnia and Sleep-Onset Dysomnia; feeding disorders, including the need to address overeating and overfeeding (especially given the alleged U.S. epidemic of obesity); early childhood manifestations of behavior disorders; and early symptoms and diagnosis of autism. 3. Mental disorders in the elderly, such as dementia and depression, once considered normal consequences of aging but now understood to represent mental disorders, including the need to identify specific brain structure abnormalities, biomarkers, and the many contributing biological, psychosocial, and environmental factors of mental illness in late life and to understand their roles in the elderly to better diagnose and monitor disease progression. Written for clinicians and researchers alike, this thought-provoking compendium contributes critical information that helps enhance our understanding of the causes of mental disorders, develop effective preventive and treatment interventions, and inform future editions of DSM and ICD.
Diario Oficial
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Author : Brazil
language : pt-BR
Publisher: Brazil
Release Date : 1948
Diario Oficial written by Brazil and has been published by Brazil this book supported file pdf, txt, epub, kindle and other format this book has been release on 1948 with Law categories.
Revista da propriedade industrial.
The Ethics Of Biomedical Research
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Author : Baruch A. Brody
language : en
Publisher: Oxford University Press, USA
Release Date : 1998
The Ethics Of Biomedical Research written by Baruch A. Brody and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
Examines the many ethical issues related to biomedical research, including the use of animals in research, research on human subjects, clinical trials, international research ethics policies, and other related topics.
Calculo Volume 2
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Author : James Stewart
language : pt
Publisher:
Release Date : 2017-03-09
Calculo Volume 2 written by James Stewart and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-09 with categories.
Cálculo foi escrito originalmente na forma de um curso. Sempre dando ênfase à compre- ensão dos conceitos, James Stewart inicia a obra oferecendo uma visão geral do assunto para, em seguida, apresentá-lo em detalhes, por meio da formulação de problemas, exercícios, tabelas e gráfi cos. A obra está dividida em dois volumes: Vol. 1 ? capítulos 1 a 8 e Vol. 2 ? capítulos 9 a 17. Esta edição de Cálculo traz diversas inovações em relação à edição anterior: dados de exemplos e exercícios foram atualizados, novos exemplos foram incluídos, algumas resoluções de exemplos foram ampliadas e mais de 20% de exercícios em cada capítulo são novos. Assim como na edição anterior, a obra apresenta exercícios graduados, com progressão cuidadosamente planejada dos conceitos básicos até problemas complexos e desafiadores. Neste volume: equações diferenciais, equações paramétricas e coordenadas polares, sequências e séries infinitas, vetores e a geometria do espaço, funções vetoriais, derivadas parciais, integrais múltiplas, cálculo vetorial, equações diferenciais de segunda ordem.
Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22
Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Why Psychoanalysis
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Author : Elisabeth Roudinesco
language : en
Publisher: Columbia University Press
Release Date : 2004-03-10
Why Psychoanalysis written by Elisabeth Roudinesco and has been published by Columbia University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-10 with Medical categories.
Why do some people still choose psychoanalysis-Freud's so-called talking cure-when numerous medications are available that treat the symptoms of psychic distress so much faster? Elisabeth Roudinesco tackles this difficult question, exploring what she sees as a "depressive society": an epidemic of distress addressed only by an increasing reliance on prescription drugs. Far from contesting the efficacy of new medications like Prozac, Zoloft, and Viagra in alleviating the symptoms of any number of mental or nervous conditions, Roudinesco argues that the use of such drugs fails to solve patients' real problems. In the man who takes Viagra without ever wondering why he is suffering from impotence and the woman who is given antidepressants to deal with the loss of a loved one, Roudinesco sees a society obsessed with efficiency and desperate for the quick fix. She argues that "the talking cure" and pharmacology represent not just different approaches to psychiatry, but different worldviews. The rush to treat symptoms is itself symptomatic of an antiseptic and depressive culture in which thought is reduced to the firing of neurons and desire is just a chemical secretion. In contrast, psychoanalysis testifies to human freedom and the power of language.