Pratos T Picos Do Pantanal Vol I Ii Iii Iv
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Carotenoids Properties Processing And Applications
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Author : Charis M. Galanakis
language : en
Publisher: Academic Press
Release Date : 2019-08-27
Carotenoids Properties Processing And Applications written by Charis M. Galanakis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Technology & Engineering categories.
Carotenoids: Properties, Processing, and Applications fills the gap of transfer knowledge between academia and industry, covering integral information in three critical dimensions: properties, recovery and applications. At the moment, carotenoid research is directed at particular applications, including colorants, antioxidants and recovery from plant processing by-products. These trends take into account the health, nutrition and functions of carotenoids, the new recovery efforts from underutilized sources, the extraction procedures using green solvents and technologies, and their sustainability aspects. Written by a team of experts in the field of food chemistry, food science and technology, as well as bioresource technologists mainly from academia, the book covers the most recent advances in the field of carotenoids, while also analyzing the potential of already commercialized processes and products. Covers carotenoids’ properties in view of alternative sources (plant by-products, microalgae, etc.), recovery technologies and applications Thoroughly explores mechanistic aspects, dietary intake and recommendations surrounding the health-promoting effects of carotenoids Discusses the effect of processing and storage conditions in carotenoid levels and bioavailability Presents applications and case studies in the food industry
Encyclopedia Of Tribology
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Author : C. Kajdas
language : en
Publisher: Elsevier
Release Date : 1990-10-09
Encyclopedia Of Tribology written by C. Kajdas and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-10-09 with Science categories.
The multidisciplinary nature of tribology, the conflicting theories and approaches to it found in the literature, plus the fact that definitions of the same phenomenon often differ widely, prompted the authors to compile this work. The aim of this encyclopedia is to provide information on specific tribological terms. The entire field of tribology encompassing lubrication, friction and wear, i.e. the science and technology of interacting surfaces in relative motion, is covered. An extensive description of the chemical and biological aspects of tribology is given, including a wide range of current references and authors. The reader is also referred to relevant literature for most of the terms listed. The information presented has been made as up-to-date as possible, taking into account both the theoretical and practical nature of the subject.The encyclopedia will be an indispensable reference source in the work of engineers, chemists, physicists, metallurgists, materials and surface scientists, biotechnologists, as well as research workers in these fields.
The Oceans And Climate
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Author : Grant R. Bigg
language : en
Publisher: Cambridge University Press
Release Date : 2003-12-11
The Oceans And Climate written by Grant R. Bigg and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-11 with Science categories.
The oceans are an integral and important part of the climate system. The Oceans and Climate introduces the multi-disciplinary controls on air-sea interaction - physical, chemical and biological - and shows how these interact. It demonstrates how the ocean contributes to, and is affected by, climate processes on timescales from seasonal to millennial and longer. Past, present and future relationships between the ocean and climate are discussed. The new edition of this successful textbook has been completely updated throughout, with extensive new material on thermohaline processes in the ocean and their link to both abrupt climate change and longer-term climate change. It will prove an ideal course and reference book for undergraduate and graduate students studying earth and environmental sciences, oceanography, meteorology and climatology. The book will also be useful for students and teachers of geography, physics, chemistry and biology.
Participatory Methods Toolkit
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Author : Nikki Slocum
language : en
Publisher:
Release Date : 2003
Participatory Methods Toolkit written by Nikki Slocum and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Mainstreaming Biodiversity For Sustainable Development
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-07-10
Mainstreaming Biodiversity For Sustainable Development written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-10 with categories.
Drawing on experiences and insights from 16 megadiverse countries, this report examines how biodiversity is being mainstreamed in four key areas.
The Golden Age Of Brazil 1695 1750
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Author : C. R. Boxer
language : en
Publisher: Univ of California Press
Release Date : 1962-01-01
The Golden Age Of Brazil 1695 1750 written by C. R. Boxer and has been published by Univ of California Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1962-01-01 with History categories.
When Brazil's 'golden age' began, the Portuguese were securely established on the coast and immediate hinterland. European rivals - Spanish, French, Dutch - had been repelled, and expansion into the vast interior had begun. By the end of the 'golden age', bandleirantes, missionaries, miners, planters and ranchers had penetrated deep into the continent. In 1750, by the Treaty of Madrid, Spain recognized Brazil's new frontiers. The colony had come to occupy an area slightly greater than that of the ten Spanish colonies in South America put together. Despite conflicts, the fusion of Portuguese, Amerindian and African into a Brazilian entity had begun; and the explosive expansion of Brazil had laid the foundation for the independence that followed in 1822. Professor Boxer deals not only with the turbulent events of the 'golden age' but analyses the economic and administrative changes of the period. He examines the relationships of officials with colonists, of settlers with Indians, of colony with mother country. Professor Boxer's classic study of a critical period in the growth of Brazil (the world's fifth largest country) has long been out of print. It is here reissued with numerous illustrations.
Travels In Brazil
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Author : Henry Koster
language : en
Publisher:
Release Date : 1817
Travels In Brazil written by Henry Koster and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1817 with categories.
External Morphology Of The Genus Aegla Crustacea Anomura Aeglidae
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Author : Joel W. Martin
language : en
Publisher:
Release Date : 1988
External Morphology Of The Genus Aegla Crustacea Anomura Aeglidae written by Joel W. Martin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
Crocodiles
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Author : John B. Thorbjarnarson
language : en
Publisher: IUCN
Release Date : 1992
Crocodiles written by John B. Thorbjarnarson and has been published by IUCN this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Nature categories.
This Action Plan describes the conservation status of 23 species of the order Crocodylia found worldwide. The plan is arranged in three principal sections: an Introductory overview, Country accounts, and Species accounts. Each Country account describes the status of wild populations, and current management programmes. The Species accounts summarise the conservation status, principle threats, and existing management programmes and then describe the ecology and natural history of the species and set out recommended priority conservation projects.