Sum Rio Executivo
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Betsy Tacy And Tib
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Author : Maud Hart Lovelace
language : en
Publisher: Harper Collins
Release Date : 2011-05-17
Betsy Tacy And Tib written by Maud Hart Lovelace and has been published by Harper Collins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-17 with Juvenile Fiction categories.
Three of a Kind Betsy and Tacy are best friends. Then Tib moves into the neighborhood and the three of them start to play together. The grown-ups think they will quarrel, but they don't. Sometimes they quarrel with Betsy's and Tacy's bossy big sisters, but they never quarrel among themselves. They are not as good as they might be. They cook up awful messes in the kitchen, throw mud on each other and pretend to be beggars, and cut off each other's hair. But Betsy, Tacy, and Tib always manage to have a good time. Ever since their first publication in the 1940s, the Betsy-Tacy stories have been loved by each generation of young readers.
Transforming Brazil
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Author : Mauricio Augusto Font
language : en
Publisher: Rowman & Littlefield
Release Date : 2003
Transforming Brazil written by Mauricio Augusto Font and has been published by Rowman & Littlefield this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Business & Economics categories.
This book re-examines the relationship between development strategy and political regime in twentieth-century Brazil. The first part of the study examines the beginning in the 1920s and 1930s of the centralized regime and state-centered development model later challenged in the 1980s, taking into account the economic and political role of Sao Paulo relative to the federal government. The analysis provides a distinctive account of the regime ruling Brazil from the 1930s through the 1980s. The second part focuses on the process of economic and political change in the 1980s and 1990s, paying particular attention to the Cardoso administration.
Host Bibliographic Record For Boundwith Item Barcode 30112100650693 And Others
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Author :
language : en
Publisher:
Release Date : 2013
Host Bibliographic Record For Boundwith Item Barcode 30112100650693 And Others written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Assessing The Quality Of Democracy
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Author : Larry Diamond
language : en
Publisher: JHU Press
Release Date : 2005-11-25
Assessing The Quality Of Democracy written by Larry Diamond and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-25 with Political Science categories.
Publisher description
Doing Business In 2004
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Author : Simeon Djankov
language : en
Publisher: World Bank Publications
Release Date : 2004
Doing Business In 2004 written by Simeon Djankov and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Juvenile Nonfiction categories.
A co-publication of the World Bank, International Finance Corporation and Oxford University Press
Wastewater Characteristics Treatment And Disposal
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Author : Marcos Von Sperling
language : en
Publisher: IWA Publishing
Release Date : 2007-03-30
Wastewater Characteristics Treatment And Disposal written by Marcos Von Sperling and has been published by IWA Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-30 with Science categories.
Wastewater Characteristics, Treatment and Disposal is the first volume in the series Biological Wastewater Treatment, presenting an integrated view of water quality and wastewater treatment. The book covers the following topics: wastewater characteristics (flow and major constituents) impact of wastewater discharges to rivers and lakes overview of wastewater treatment systems complementary items in planning studies. This book, with its clear and practical approach, lays the foundations for the topics that are analysed in more detail in the other books of the series. About the series: The series is based on a highly acclaimed set of best selling textbooks. This international version is comprised by six textbooks giving a state-of-the-art presentation of the science and technology of biological wastewater treatment. Other titles in the series are: Volume 2: Basic Principles of Wastewater Treatment; Volume 3: Waste Stabilisation Ponds; Volume 4: Anaerobic Reactors; Volume 5: Activated Sludge and Aerobic Biofilm Reactors; Volume 6: Sludge Treatment and Disposal
The Takeover Of Social Policy By Financialization
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Author : Lena Lavinas
language : en
Publisher: Springer
Release Date : 2017-03-25
The Takeover Of Social Policy By Financialization written by Lena Lavinas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-25 with Business & Economics categories.
This book critically addresses the model of social inclusion that prevailed in Brazil under the rule of the Workers Party from the early 2000s until 2015. It examines how the emergence of a mass consumer society proved insufficient, not only to overcome underdevelopment, but also to consolidate the comprehensive social protection system inherited from Brazil’s 1988 Constitution. By juxtaposing different theoretical frameworks, this book scrutinizes how the current finance-dominated capitalism has reshaped the role of social policy, away from rights-based decommodified benefits and towards further commodification. This constitutes the Brazilian paradox: how a center-left government has promoted and boosted financialization through a market incorporation strategy using credit as a lever for expanding financial inclusion. In so doing, it has pushed the subjection of social policy further into the logic of financial markets.
Routledge Handbook Of Physical Cultural Studies
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Author : Michael L. Silk
language : en
Publisher: Routledge
Release Date : 2017-02-10
Routledge Handbook Of Physical Cultural Studies written by Michael L. Silk and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-10 with Social Science categories.
Physical cultural studies (PCS) is a dynamic and rapidly developing field of study. This handbook offers the first definitive account of the state of the art in PCS, showcasing the latest research and methodological approaches. It examines the boundaries, preoccupations, theories and politics of PCS, drawing on transdisciplinary expertise from areas as diverse as sport studies, sociology, history, cultural studies, performance studies and anthropology. Featuring chapters written by world-leading scholars, this handbook examines the most important themes and issues within PCS, exploring the active body through the lens of class, age, gender, sexuality, race, ethnicity, (dis)ability, medicine, religion, space and culture. Each chapter provides an overview of the state of knowledge in a particular subject area, while also considering possibilities for developing future research. Representing a landmark contribution to physical cultural studies and allied fields, the Routledge Handbook of Physical Cultural Studies is an essential text for any undergraduate or postgraduate course on physical culture, sports studies, leisure studies, the sociology of sport, the body, or sport and social theory.
Strategic Employee Communication
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Author : Gail S. Thornton
language : en
Publisher: Springer
Release Date : 2018-10-06
Strategic Employee Communication written by Gail S. Thornton and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-06 with Business & Economics categories.
Employee engagement (or a lack thereof) can often be linked to poor communication and a detachment from company goals. Companies of all sizes are looking for ways to boost communication, recognizing its impact on key business outcomes, such as productivity and profitability. This book offers fresh insights about opportunities to improve the quality of employee communications based on employees’ needs. It highlights the importance of simple, jargon-free communication that focuses on dialogue and content. High-performing organizations are more likely to think about communication from the audience perspective, rather than purely from the management perspective. The case studies offer readers a firm understanding of ways to implement and measure communication in daily practice. Effective communication requires planning and this book, with its focus on the US, Latin America, and emerging markets, will guide readers in using communication in the alignment of corporate and employee needs.