Surgery And Inflammatory Bowel Disease
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Cancer And Reconstructive Surgery In Inflammatory Bowel Disease
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Author : Maie Abdalla
language : en
Publisher: Linköping University Electronic Press
Release Date : 2019-11-04
Cancer And Reconstructive Surgery In Inflammatory Bowel Disease written by Maie Abdalla and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-04 with categories.
Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon. According to the literature, some thirty percent of UC patients may require a subtotal colectomy and ileostomy due to failure of medical treatment, acute toxic colitis or dysplasia/cancer diagnosis. Some patients choose to get continence restored with either an ileorectal anastomosis (IRA) or an ileal pouch-anal anastomosis (IPAA). Worldwide most surgeons prefer an IPAA to an IRA, despite reports of pouchitis, impaired fertility and fecundity. Fear of recurring proctitis and fear of rectal cancer in the remaining rectum is contributing to the choice of an IPAA. Little is known regarding the outcomes of IRA compared with IPAA in UC patients. We aimed to investigate the anorectal function, quality of life (QoL), risk of failure and rectal cancer in patients with UC restored with IRA and IPAA respectively. Methods: Data about all Inflammatory bowel disease (IBD) patients was obtained from the Swedish National Patient Register (NPR) between 1964-2014 and in one study from the Linköping University Hospital medical records 2006-2012. Patients who developed cancer were identified from the Swedish National Cancer Register. We investigated the risk of cancer and inflammation, functional outcome and failure as well as the quality of life for IRA and IPAA patients. Investigation of risk for cancer in IRA and IPAA compared with the background population was performed using survival analytic techniques: uni-and multivariate regression, Kaplan Meier curves and standardized incidence ratio. Results: Twelve percent (7,889 /63,795) of UC patients required colectomy according to the NPR. The relative risk for rectal cancer among patients with an IRA was increased (SIR 8.7). However, the absolute risk was 1.8% after a mean follow up of 8.6 years and the cumulative risk 10- and 20-years after IRA was 1.6% and 5.6%, respectively. Risk factors for rectal cancer were primary sclerosing cholangitis in patients with an IRA (hazard ratio 6.12), and severe dysplasia or cancer of the colon prior to subtotal colectomy in patients with a diverted rectum in place (hazard ratio 3.67). Regarding IPAA, the relative risk to develop rectal cancer was (SIR 0.4) compared with the background population and the absolute risk was only 0.06% after a mean of 12.2 years of follow up. Among patients operated at the Linköping University Hospital: IRA patients reported better overall continence according to the Öresland score with in median3 (IQR 2–5) for IRA (n=38) and 10 (IQR 5–15) for IPAA (n=39, p<0.001). There were no major differences regarding the QoL. According to the NPR, after a median follow up of 12.4 years failure occurred in 265(32%) out of 1112 patients, of which 76 were secondarily reconstructed with an IPAA. Failure of the IPAA occurred in 103 (6%) patients with primary and in 6 (8%) patients after secondary IPAA (log-rank p=0.38). Conclusion: IRA is a safe restorative procedure for selected UC patients. Patients should be aware of the annual postoperative endoscopic evaluation with biopsies as well as the need to the use of local anti-inflammatory preparations. However, IRA should not be offered for UC patients with an associated primary sclerosing cholangitis diagnosis due to the increased risk to develop rectal cancer in their rectal mucosa. In such case, IPAA is probably the treatment of choice.
Inflammatory Bowel Disease An Issue Of Surgical Clinics
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Author : Sean J. Langenfeld
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-12-19
Inflammatory Bowel Disease An Issue Of Surgical Clinics written by Sean J. Langenfeld and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-19 with Medical categories.
This issue of Surgical Clinics of North America focuses on Inflammatory Bowel Disease and is edited by Dr. Sean Langenfeld. Articles will include: IBD presentation and diagnosis; Endoscopy in IBD; Preoperative considerations in IBD; Postoperative Considerations in IBD; IBD and cancer/dysplasia; Elective abdominal surgery for IBD; Abdominal emergencies in IBD; Anorectal Crohn’s disease; Other surgeries in IBD patients; Pediatric inflammatory bowel disease; Pouch complications; Genetic and environmental considerations for IBD; IBD and short bowel syndrome; Medical Management of IBD; and more!
Mastery Of Ibd Surgery
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Author : Neil Hyman
language : en
Publisher: Springer
Release Date : 2019-05-29
Mastery Of Ibd Surgery written by Neil Hyman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-29 with Medical categories.
This book provides a guide to the management of patients with Crohn’s disease and ulcerative colitis. The indications for surgery within inflammatory bowel disease are covered, as well as new biologic medications and the effects they have on the immune system. Details on how these drugs should be managed to avoid complications and ensure patient safety are also included. Mastery of IBD Surgery sets out to cover surgical responses to inflammatory bowel disease from a multidisciplinary perspective and aims to help all surgeons and medical professionals working in this area. This book is relevant to colorectal surgeons, gastrointestinal surgeons, and gastroenterologists.
Inflammatory Bowel Disease An Issue Of Surgical Clinics
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Author : Kerry L. Hammond
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-01-07
Inflammatory Bowel Disease An Issue Of Surgical Clinics written by Kerry L. Hammond and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-07 with Medical categories.
Inflammatory Bowel Disease is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Inflammatory Bowel Disease: Historical Perspective, Epidemiology and Risk Factors; Diagnostic Modalities for Inflammatory Bowel Disease: Serologic Markers and Endoscopy; Diagnostic Modalities for Inflammatory Bowel Disease: Radiologic Imaging; Medical Therapy for Inflammatory Bowel Disease; Crohn's Disease of the Foregut and Small Intestine; Crohn's Disease of the Colon, Rectum and Anus; Indications and Options for Surgery in Ulcerative Colitis; Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease; Extraintestinal Manifestations of Inflammatory Bowel Disease; Colorectal Neoplasia and Inflammatory Bowel Disease; Nutritional Support of the Inflammatory Bowel Disease Patient; Psychosocial Support of the Inflammatory Bowel Disease Patient; Genetics and Pathogenesis of Inflammatory Bowel Disease; and more!
Operative Strategies In Inflammatory Bowel Disease
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Author : Fabrizio Michelassi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Operative Strategies In Inflammatory Bowel Disease written by Fabrizio Michelassi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
A thorough review of the operative techniques as well as the indications, pitfalls, strategies and timing, complications, and long term results involved in the surgical treatment of ulcerative colitis and Crohn's Disease. As IBD is characterised by a high incidence of re-operations and complications, independent sections of the text are devoted entirely to surgical treatment of specific complications and the management of recurrent diseases. Exquisitely illustrated with over 200 line drawings, this book contains important information on medical treatment, endoscopic evaluation, pathology, radiology, and aetiology.
Crohn S Disease
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Author : Alessandro Fichera
language : en
Publisher: Springer
Release Date : 2015-08-20
Crohn S Disease written by Alessandro Fichera and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-20 with Medical categories.
Crohn’s Disease: Basic Principles provides a comprehensive and state-of-the-art overview of the current diagnosis and treatment strategies for Crohn’s disease. Care of these patients and clinical conditions can be quite complex and often require a multidisciplinary approach. Sections of the book are based on the most current, evidenced-based resources and have been structured to review the etiology and diagnosis of Crohn’s disease, discuss advances in medical and surgical treatment, illustrate emerging technologies impacting the care of patients with Crohn’s disease, and examine functional and quality of life outcomes in this patient population. The text reviews our understanding of the influence of molecular and genetic factors in the development and pattern of Crohn’s disease. Current methods of diagnosis and strategies in the medical management of patients with Crohn’s disease are evaluated including the use of biologic agents. Resection and bowel sparing techniques for primary and recurrent disease as well as advances in endoscopy and laparoscopy are discussed in detail. In addition, factors influencing the quality of life of patients with Crohn’s disease are examined including nutrition, enterostomal care, fertility, and sexual function. Written by recognized experts in their field, Crohn’s Disease: Basic Principles highlights the integrated multidimensional aspect of caring for patients with Crohn’s disease and will be of great value to colon and rectal surgeons, general surgeons, gastroenterologists, internists, as well as fellows and upper level residents in training training.
Crohn S Disease
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Author : Roberto Tersigni
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-13
Crohn S Disease written by Roberto Tersigni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-13 with Medical categories.
Crohn's disease is an inflammatory bowel disease, whose symptoms are similar to other intestinal disorders, such as irritable bowel syndrome and ulcerative colitis; it can therefore be difficult to diagnose. Its knowledge and understanding have increased considerably in the last years; new advances in genetics, medical and surgical management offer today new possibilities for patients suffering from an inflammatory bowel disease. However, Crohn's disease remains a difficult disease to deal with, both from a research and clinical point of view. This book provides general practitioners with a basic knowledge of the disease, offering in the same time an update on new facts about Crohn's disease to specialists. It can also be useful for residents willing to develop a deeper knowledge of inflammatory bowel diseases.
Mastery Of Ibd Surgery
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Author : Neil Hyman
language : en
Publisher:
Release Date : 2019
Mastery Of Ibd Surgery written by Neil Hyman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Inflammatory bowel diseases categories.
This book provides a guide to the management of patients with Crohn's disease and ulcerative colitis. The indications for surgery within inflammatory bowel disease are covered, as well as new biologic medications and the effects they have on the immune system. Details on how these drugs should be managed to avoid complications and ensure patient safety are also included. Mastery of IBD Surgery sets out to cover surgical responses to inflammatory bowel disease from a multidisciplinary perspective and aims to help all surgeons and medical professionals working in this area. This book is relevant to colorectal surgeons, gastrointestinal surgeons, and gastroenterologists.
Inflammatory Bowel Disease
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Author : Sami Karoui
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-01-27
Inflammatory Bowel Disease written by Sami Karoui and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-27 with Medical categories.
This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such as intestinal barrier dysfunction and the roles of TH 17 cells and IL 17 in the immune response in inflammatory bowel disease. The book also focuses on several relevant clinical points, such as pregnancy during inflammatory bowel disease and the health-related quality of life as an end point of the different treatments of the diseases. Finally, advances in management of patients with inflammatory bowel disease are discussed, especially in a complete review of the recent literature.
Crohn S Disease And Ulcerative Colitis
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Author : Devinder Kumar
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Crohn S Disease And Ulcerative Colitis written by Devinder Kumar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
A gem among surgical manuals, this comprehensive guide to Crohn's disease and ulcerative colitis is an excellent source for all surgeons looking specifically for technical details about the surgical management of these two diseases. Its authors - both involved in multi-center international trials, working parties and symposia - capture in print the improved techniques that have brought about revolutionary developments in the field. The extremely practical approach makes it easy for surgeons to review the indications for surgical interventions and the surgical options available for each clinical problem. Step-by-step operative instructions with practical tips born of long experience are given. The authors point out what results one should expect following the surgical intervention; these include zero mortality and minimal morbidity. They also list all the steps that should be taken to minimize the risk of late complications or recurrence. The clear instructions in this manual will also be of great value to non-surgical physicians who wish to know the indications for surgical treatment and what results they should expect from their surgical colleagues.