T H Umor
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Tumors And Tumor Like Conditions Of The Lung And Pleura E Book
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Author : Cesar A. Moran
language : en
Publisher: Elsevier Health Sciences
Release Date : 2010-03-22
Tumors And Tumor Like Conditions Of The Lung And Pleura E Book written by Cesar A. Moran and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-22 with Medical categories.
Tumors and Tumor-like Conditions of the Lung and Pleura is a superb visual resource that brings the state-of-the-art in thoracic diagnosis straight to the lab bench. Cesar A. Moran and Saul Suster are internationally recognized experts in pulmonary pathology who present a coherent and consistent approach to interpretation and diagnosis. Through more than 900 stunning photographs and a consistent, user-friendly format, this resource provides quality guidance on the diagnostic problems you face in everyday practice. You’ll get a host of innovative, practice-oriented features unavailable in any other text that streamline and facilitate diagnostic decision-making. Written by practitioners for practitioners, this visual resource is designed for quick and easy use. You can’t afford to be without it. Features over 900 high-quality full-color illustrations so you can recognize and diagnose any tissue sample under the microscope. Presents immunohistochemical and genetic features wherever relevant for comprehensive information on all of the investigative contexts important to formulating an accurate diagnosis. Includes summary tables throughout the text to simplify and clarify complex discussions and enable "at a glance" comparisons between entities. Provides practical advice from experts on pitfalls in differential diagnosis to help you avoid diagnostic errors.
Brain Tumors
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Author : Francis Ali-Osman
language : en
Publisher: Springer Science & Business Media
Release Date : 2005
Brain Tumors written by Francis Ali-Osman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Exciting new developments and discoveries of the last two decades are beginning to shed light on the complex biology of brain tumors and are advancing our understa- ing of the cellular and molecular processes involved in their initiation, progression, and clinical and biological behavior. The disease process in brain tumors is quite complex and the resulting tumors are characterized by a high degree of biological and clinical diversity. Thus, despite the advances of the last two decades, prognosis for patients with malignant brain tumors remains abysmal. Significant progress in the diagnosis, treatment and, ultimately, prevention of these tumors will require both the timely h- nessing of the advances in basic and clinical brain tumor research, and a continuing concerted effort at increasing our understanding of brain tumor biology, in particular, the molecular genetic changes and perturbations of cellular pathways involved in brain oncogenesis and which drive the biological and clinical behavior of the tumors. Brain tumor diagnosis and prognosis, which is still largely based on histopathology and other clinical criteria, will, in the future, acquire a significant molecular component, with the incorporation of knowledge of genes that are mutated, over-expressed, deleted, silenced, or functionally altered in the tumors. Treatment strategies for brain tumors, rather than being empirical, will be rationally developed based on an understanding of the cellular and molecular mechanisms and targets that have been activated, suppressed, or otherwise altered.
The Tumor Microenvironment Of High Grade Serous Ovarian Cancer
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Author : M. Sharon Stack
language : en
Publisher: MDPI
Release Date : 2019-02-06
The Tumor Microenvironment Of High Grade Serous Ovarian Cancer written by M. Sharon Stack and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with Biology (General) categories.
This book is a printed edition of the Special Issue "The Tumor Microenvironment of High Grade Serous Ovarian Cancer" that was published in Cancers
Tumor Immune Microenvironment In Cancer Progression And Cancer Therapy
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Author : Pawel Kalinski
language : en
Publisher: Springer
Release Date : 2017-12-22
Tumor Immune Microenvironment In Cancer Progression And Cancer Therapy written by Pawel Kalinski and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-22 with Medical categories.
The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.
Current Advances In The Science Of Osteosarcoma
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Author : Eugenie S. Kleinerman
language : en
Publisher: Springer
Release Date : 2020-07-30
Current Advances In The Science Of Osteosarcoma written by Eugenie S. Kleinerman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-30 with Medical categories.
This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.
Tumors Of The Spinal Canal
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Author : Simon Hanft
language : en
Publisher: Springer Nature
Release Date : 2020-11-13
Tumors Of The Spinal Canal written by Simon Hanft and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Medical categories.
This book presents a focused, case-oriented approach to a specific disease entity: tumors located within the spinal canal. Each tumor type constitutes its own chapter and additional chapters focus on more novel trends in the field, such as radiosurgery and minimally invasive surgical techniques. In each chapter, the authors provide expert opinions on preoperative goals, intraoperative techniques and decision-making, and postoperative paradigms, including surveillance guidelines and thresholds for initiating adjuvant therapy. The management of intradural tumors has become increasingly interdisciplinary, and one of the major goals of this text is to familiarize the treating neurosurgeon with the latest advances in both operative and non-operative strategies. The text seeks to answer two questions: 1) what are the detailed surgical steps taken by these neurosurgeons to ensure safe maximal resection of these tumors? and 2) in cases of residual and recurrent disease, what are the most effective management options? Consensus regarding definitive management remains difficult to reach given the overall rarity of these tumors. Tumors of the Spinal Canal is ultimately a practical reference drawn from the experiences of its individual authors, a compendium of surgical pearls, pitfalls, and preferences, all steeped in the most recent and relevant literature on the subject.
Atlas Of Clinical Cases On Brain Tumor Imaging
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Author : Yelda Özsunar
language : en
Publisher: Springer
Release Date : 2020-04-29
Atlas Of Clinical Cases On Brain Tumor Imaging written by Yelda Özsunar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-29 with Medical categories.
This book presents and analyzes clinical cases of brain tumors and follows the classification provided by the WHO in 2016. After introductory chapters reviewing the international literature on the topic, the advances made in all imaging modalities (especially Magnetic Resonance and Computed Tomography) are examined.All radiological findings are supplemented with a wealth of images and brief explanations. The clinical information is given as part of the case discussion, as are the characteristics and differential diagnosis of the tumors. Radiologic-pathologic correlations round out the description of each clinical case.Intended as a quick and illustrative reference guide for radiology residents and medical students, this atlas represents the most up-to-date, practice-oriented reference book in the field of Brain Tumor Imaging.
Tumor Dormancy Quiescence And Senescence Volume 2
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Author : M. A. Hayat
language : en
Publisher:
Release Date : 2013-12-31
Tumor Dormancy Quiescence And Senescence Volume 2 written by M. A. Hayat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-31 with categories.
Tumor Suppressor Par 4
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Author : Vivek M. Rangnekar
language : en
Publisher: Springer Nature
Release Date : 2022-01-08
Tumor Suppressor Par 4 written by Vivek M. Rangnekar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-08 with Medical categories.
Par-4 is a tumor suppressor protein first discovered and identified in 1993 by Dr. Vivek Rangnekar’s laboratory in prostate cancer cells undergoing apoptosis. Par-4 (later also known as PAWR) is a naturally occurring tumor suppressor. Studies have indicated that Par-4 selectively induces apoptosis in cancer cells while leaving normal, healthy, cells unaffected. Mechanisms contributing to the cancer-selective action of Par-4 have been associated with protein kinase A activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. Par-4 is downregulated, inactivated or mutated in diverse cancers. This first of two volumes will be the first on the market on the topic of Par-4, and will provide the opportunity for researchers to discuss the future direction of studies, broaden the scope of research, and contribute a more complete understanding of the molecule’s structural features, key functional domains, regulation and relevant basic and clinical/translational facets.
Journal Of The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 2005
Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Cancer categories.