Um Touro Solit Rio
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Santa Mar A Del Monte
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Author : Ruth Behar
language : en
Publisher:
Release Date : 1986
Santa Mar A Del Monte written by Ruth Behar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with León (Spain : Province) categories.
The description for this book, Santa Maria del Monte: The Presence of the Past in a Spanish Village, will be forthcoming.
The Spelit Power Matrix
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Author : June H. Schmieder-Ramirez
language : en
Publisher: Createspace Independent Pub
Release Date : 2007-05-30
The Spelit Power Matrix written by June H. Schmieder-Ramirez and has been published by Createspace Independent Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-30 with Business & Economics categories.
The SPELIT POWER MATRIX is a leadership tool for untangling the organizational environment from a social, political, economic, legal, intercultural and technical view. The SPELIT analysis method was developed for adult learners to have a framework for determining and formulating the answer to the question: What is? There is a need to analyze the environment in all organizations, whether you are entering a new organization or to benchmark the existing organization. The purpose of this text is to show how perceptive leaders can analyze environments in preparation for possible future action. We demonstrate how the methodology aligns with previous theories regarding environmental scanning and produces a workable framework for the perceptive leader. The SPELIT POWER MATRIX is intended for practitioners doing a market analysis or diagnosis prior to implementing transitions, benchmarking in anticipation of an intervention, and can be used by undergraduate students and seasoned practitioners.
Ecstatic Encounters
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Author : Mattijs van de Port
language : en
Publisher: Amsterdam University Press
Release Date : 2011
Ecstatic Encounters written by Mattijs van de Port and has been published by Amsterdam University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Social Science categories.
"Reality does not comply with our narrations of it. And that is most certainly the case with the narrations produced in academia. An anthropologist in Bahia, Brazil, fears to become possessed by the spirits he had come to study; falls madly in love withan 'informant'; finds himself baffled by the sayings of a clairvoyant; and has to come to grips with the murder of one of his best friends. Unsettling events that do not belong to the orderly world of scientific research, yet leave their imprint on the way the anthropologist comes to understand the world. REflecting on his long research experience with the spirit possession cult Candomblâe, the author shows, in a probing manner, how definitions of reality always require the exclusion of certain perceptions, experiences and insights. And yet, this 'rest-of-what-is' turns out to be an inexhaustible source of amazement, seduction and renewal." --P [4] of cover.
Bio Geotechnologies For Mine Site Rehabilitation
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Author : M.N.V. Prasad
language : en
Publisher: Elsevier
Release Date : 2018-01-10
Bio Geotechnologies For Mine Site Rehabilitation written by M.N.V. Prasad and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-10 with Science categories.
Bio-Geotechnologies for Mine Site Rehabilitation deals with the biological, physical, chemical, and engineering approaches necessary for the reclamation of mine waste. As mining has negative effects on natural resources and deteriorates the quality of the surrounding environment, this book provides coverage across different types of mining industries, which are currently creating industrial deserts overloaded with technogenic waste. The book offers cost-effective strategies and approaches for contaminated sites, along with remediation and rehabilitation methods for contaminated soils and waste dumps. It is an essential resource for students and academics, but is also ideal for applied professionals in environmental geology, mineral geologists, biotechnologists and policymakers. Deals with global and holistic approaches of abandoned mine land rehabilitation Includes mine waste rehabilitation case studies from around the world Covers integrated technologies, such as bioremediation of metalliferous soil Provide strategies for sustainable ecosystems on mine spoil dumps Offers novel methods for the remediation of acid mine drainage
The National Parks
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Author : Barry Mackintosh
language : en
Publisher:
Release Date : 1985
The National Parks written by Barry Mackintosh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with National parks and reserves categories.
The Parsing System Palavras
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Author : Eckhard Bick
language : en
Publisher:
Release Date : 2000
The Parsing System Palavras written by Eckhard Bick and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Palavras (Computer program) categories.
Originally presented as the author's thesis (doctoral--Aarhas University).
Dangerous Encounters
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Author : Daniel Touro Linger
language : en
Publisher: Stanford University Press
Release Date : 1992
Dangerous Encounters written by Daniel Touro Linger and has been published by Stanford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Social Science categories.
This book is about violence in the Brazilian city of Sao Luis. It describes how people think about and negotiate dangerous encounters - vital and disturbing experiences that, when they go wrong, yield moral failure, humiliation, and death. Brazilians, like people elsewhere, worry about the perils of coming face-to-face with the wrong person, at the wrong time, under the wrong circumstances. The book discusses two conceptually linked forms of perilous face-to-face encounters: Carnival, a bacchanalian festival, and briga, a potentially lethal street confrontation. When playing becomes fighting, Carnival's samba, fueled by the controlled venting of dangerous passions, gives way to the explosive pas de deux of the street fight. Sao-luisenses tell vivid, sometimes terrifying, stories of verbal and physical confrontations. Their narratives, based on cultural models of Carnivals and brigas, highlight the vulnerability of the self to humiliation by others and the vulnerability of moral controls to one's own hostile emotions. The book argues that this double sense of social and psychological vulnerability is a product of Brazilian interpersonal relations, which are profoundly marked by the arbitrary exercise of power and the stifling of resentment in subordinates. Culture here consists not of shared symbols but of shared quandaries. The author suggests that Brazilian street fighting is an alarm bell - an inarticulate representation of pressing but poorly understood social and psychological dilemmas. Violence in Sao Luis may therefore be a desperate attempt to understand and come to grips with the very resentment, rooted in the city's harsh social transactions, that engenders it.
Historic Cities And Sacred Sites
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Author : Ismail Serageldin
language : en
Publisher: World Bank Publications
Release Date : 2001-01-01
Historic Cities And Sacred Sites written by Ismail Serageldin and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-01 with Social Science categories.
This book contributes to a better understanding of why historic cities and sacred sites are important, and how cultural roots may influence and improve urban futures. It emphasises the need to include social and cultural dimensions in economic development and offers cases of best practice.
Minority Government And Majority Rule
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Author : Kaare Strøm
language : en
Publisher: Cambridge University Press
Release Date : 1990-04-27
Minority Government And Majority Rule written by Kaare Strøm and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-04-27 with Philosophy categories.
Examines minority governments to show they are not exceptional or unstable.