A Nobel Fellow On Every Floor
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A Nobel Fellow On Every Floor
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Author : John Finch
language : en
Publisher: Icon Books
Release Date : 2024-06-07
A Nobel Fellow On Every Floor written by John Finch and has been published by Icon Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-07 with Science categories.
In Cambridge in the 1950s, several research groups funded by the Medical Research Council were producing exciting results. In the Biochemistry Department, Sanger determined the amino acid sequence of insulin, and was awarded a Nobel Prize for this in 1958. At the Cavendish Laboratory, in the MRC Unit for the Study of the Molecular Structure of Biological Systems, Watson and Crick solved the structure of DNA, and Perutz and Kendrew produced the first three-dimensional maps of protein structures – haemoglobin and myoglobin – for which all four were later awarded Nobel Prizes. This made it timely to create, in 1962, a new Laboratory of Molecular Biology in Cambridge by amalgamating these groups with other MRC-funded groups from London. The Laboratory has become one of the most successful in its field, and the number of Nobel Prizes awarded over the years to scientists at LMB has risen to thirteen. This book follows the development of LMB, through the people who moved into the new Laboratory and their research. It describes events and personalities that have given the Laboratory a friendly, family atmosphere, while continuing to be scientifically productive.
Fred Sanger Double Nobel Laureate
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Author : George G. Brownlee
language : en
Publisher: Cambridge University Press
Release Date : 2014-11-06
Fred Sanger Double Nobel Laureate written by George G. Brownlee and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-06 with Biography & Autobiography categories.
The first biography of Fred Sanger, shedding light on his remarkable life and career and exploring his continuing legacy.
Nobel Prizes And Notable Discoveries
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Author : Erling Norrby
language : en
Publisher: World Scientific
Release Date : 2016-09-06
Nobel Prizes And Notable Discoveries written by Erling Norrby and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-06 with Science categories.
The present book discusses the prizes in physiology or medicine 1963-65. The 1963 prize recognized milestone discoveries in the field of neurosciences, the way electrical impulses are generated and spread in nerves. The impressive developments of insights into tantalizing brain functions, like consciousness and memory, is discussed in the perspective of prizes both before and after the 1963 prize. The prize in 1964 marked the advanced biochemical venture that led to a full understanding of the synthesis of cholesterol, a central molecule for providing flexibility of the membranes of the trillions of cell in our body. The importance of this molecule for the appearance of cardiovascular diseases and the possibilities to prevent them is presented in the light of other prizes earlier and later in this field. The 1965 prize recognized three impressive French intellectuals, Lwoff, Monod and Jacob. Their contributions allowed the full maturation of the initial phase of the emerging field of molecular biology. The comprehension of the information flow from DNA via RNA to proteins was the source of a revolution of life sciences and of medicine.
Nobel Prizes And Nature S Surprises
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Author : Erling Norrby
language : en
Publisher: World Scientific
Release Date : 2013
Nobel Prizes And Nature S Surprises written by Erling Norrby and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
Each year the Nobel Prizes in the natural sciences reveal amazing discoveries. Nominations are kept secret for 50 years after the awards have been made. Covering the awards from 1960 to 1962, this book reveals discoveries relating to the control of infectious diseases and the advent of organ transplant organs, as well as advances in molecular biology.
Nobel Prizes Genes Viruses And Cellular Signaling
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Author : Erling Norrby
language : en
Publisher: World Scientific
Release Date : 2022-09-05
Nobel Prizes Genes Viruses And Cellular Signaling written by Erling Norrby and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-05 with Science categories.
The present book discusses the Nobel Prizes in physiology or medicine from 1969 to 1971. The 1969 prize recognized Max Delbrück, Alfred Hershey and Salvador Luria. Their pioneering studies of viruses infecting bacteria, bacteriophages, from the mid-1940s through the 1950s laid the foundation for the wide field of molecular biology. The nature of the gene was finally understood. Insights into the biochemistry of the critical information molecules, the nucleic acids, opened wide vistas for interpreting their expression and the interaction of their product with other gene products.The contact between the endings of a nerve and a target cell, the synapse, has always stirred the imagination of scientists. A number of the insights gained have been highlighted by Nobel Prizes in physiology or medicine. In 1970 the prize recognized Bernard Katz, Ulf von Euler and Julius Axelrod. They had revealed how signaling substances in the nerve terminals were stored in packages, released by membrane fusion and inactivated or reused by particular metabolic events.The recipient of the 1971 Nobel Prize in physiology or medicine was a single scientist, Earl Sutherland. He had identified critical molecules in cells that allow signals elicited at their surface via a number of internal steps to influence the expression of specific genes in the nucleus. The new kind of information transmitting molecules were referred to as 'secondary messengers'. They represent a critical part of a highly complex network of signaling controlling the operative conditions of the cell by adjustments of the so-called intermediary metabolism.The widening insights into functions of specialized cells and their complex interactions have led to the development of many kinds of remedies.
Frederick Sanger
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Author : Joe S. Jeffers
language : en
Publisher: Springer
Release Date : 2017-03-14
Frederick Sanger written by Joe S. Jeffers and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-14 with Science categories.
In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.
A Place In History
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Author : Paul M. Wassarman
language : en
Publisher: Oxford University Press, USA
Release Date : 2020
A Place In History written by Paul M. Wassarman and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Science categories.
John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the twentieth century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today. In this book, Paul M. Wassarman, a postdoctoral fellow with Kendrew in the late 1960s, delves into Kendrew's personal and scientific life to uncover the background, traits, and experiences of the man responsible for so many achievements within science and beyond. Wassarman shares previously unpublished stories of Kendrew, including his vital role in the rise of molecular biology at three world-famous scientific institutions: the Cavendish Laboratory, Laboratory of Molecular Biology, and European Laboratory of Molecular Biology. Kendrew was an unwavering advocate for British and European science and one of the most gifted, influential, and accomplished figures in twentieth century science. A Place in History is a groundbreaking account of Kendrew's life that is perfect for anyone interested in learning about the person behind the many achievements.
Architects Of Structural Biology
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Author : John Meurig Thomas
language : en
Publisher: Oxford University Press, USA
Release Date : 2020-02-28
Architects Of Structural Biology written by John Meurig Thomas and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-28 with Nature categories.
This is a history of the personalities and single-minded devotion of four Nobel laureates who played a pivotal role in the creation of a new and prevalent branch of biology. This led to major medical advances in one of the greatest centres of scientific research: the Laboratory of Molecular Biology in Cambridge, which they helped to establish.
The Secret Of Life Rosalind Franklin James Watson Francis Crick And The Discovery Of Dna S Double Helix
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Author : Howard Markel
language : en
Publisher: W. W. Norton & Company
Release Date : 2021-09-21
The Secret Of Life Rosalind Franklin James Watson Francis Crick And The Discovery Of Dna S Double Helix written by Howard Markel and has been published by W. W. Norton & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-21 with Science categories.
An NPR Best Book of the Year An authoritative history of the race to unravel DNA’s structure, by one of our most prominent medical historians. James Watson and Francis Crick’s 1953 discovery of the double helix structure of DNA is the foundation of virtually every advance in our modern understanding of genetics and molecular biology. But how did Watson and Crick do it—and why were they the ones who succeeded? In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel. The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin’s sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised. A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick—their competitiveness, idiosyncrasies, and youthful immaturity—and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.
Unravelling The Double Helix
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Author : Gareth Williams
language : en
Publisher: Hachette UK
Release Date : 2019-04-18
Unravelling The Double Helix written by Gareth Williams and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-18 with Science categories.
DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other researchers had assembled over decades. Researchers like Maurice Wilkins (the 'Third Man of DNA') and Rosalind Franklin, famously demonised by Watson. Not forgetting the 'lost heroes' who fought to prove that DNA is the stuff of genes, only to be airbrushed out of history. In Unravelling the Double Helix, Professor Gareth Williams sets the record straight. He tells the story of DNA in the round, from its discovery in pus-soaked bandages in 1868 to the aftermath of Watson's best-seller The Double Helix a century later. You don't need to be a scientist to enjoy this book. It's a page-turner that unfolds like a detective story, with suspense, false leads and treachery, and a fabulous cast of noble heroes and back-stabbing villains. But beware: some of the science is dreadful, and the heroes and villains may not be the ones you expect.