A Short Guide To Clinical Pharmacokinetics
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A Short Guide To Clinical Pharmacokinetics
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Author : Krishnaveni Manubolu
language : en
Publisher: Springer
Release Date : 2024-09-02
A Short Guide To Clinical Pharmacokinetics written by Krishnaveni Manubolu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-02 with Science categories.
This book is a complete resource on pharmacokinetics, pharmacodynamics and pharmacogenomics in clinical practice. It consists of seven chapters that cover various aspects of pharmacokinetics and its clinical applications. The chapters are structured to provide clear objectives and keywords are bolded throughout the text to facilitate understanding. The topics covered include the significance of pharmacokinetics in clinical practice, factors affecting pharmacokinetic parameters, pharmacokinetic drug interactions, therapeutic drug monitoring, dosage adjustment in different population groups, the influence of hepatic diseases on pharmacokinetics and the impact of pharmacogenomics on pharmacokinetics and pharmacodynamics. The book is written in simple language to make the concepts accessible to all readers. This book is a comprehensive resource for students pursuing a doctoral degree in pharmacy, as well as academicians and researchers in clinical pharmacokinetics.
Clinical Pharmacokinetics
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Author : Devarakonda Rama Krishna
language : en
Publisher: Berlin ; New York : Springer-Verlag
Release Date : 1990
Clinical Pharmacokinetics written by Devarakonda Rama Krishna and has been published by Berlin ; New York : Springer-Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
Clinical Pharmacokinetics
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Author : John E. Murphy
language : en
Publisher:
Release Date : 2012
Clinical Pharmacokinetics written by John E. Murphy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Pharmacokinetics categories.
In the complex field of pharmacokinetics, one reference guide has an identity all its own. Clinical Pharmacokinetics, the classic quick reference, comes from a distinctive voice in the field: Dr. John E. Murphy, a long-trusted source offering a straightforward, accessible approach. Now, the fully updated fifth edition brings to experienced practitioners, new practitioners, residents, and students alike the pharmacokinetic information they need most.
Clinical Pharmacokinetics
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Author : Devarakonda R. Krishna
language : en
Publisher: Springer
Release Date : 1990
Clinical Pharmacokinetics written by Devarakonda R. Krishna and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
The first part of this book enables the reader to be familiarized with basic concepts of pharmacokinetics (Absorption, Distribution, Metabolism and Excretion - ADM E) following single dose administration. In this part these principles are applied to clinically relevant situations, namely, multiple or (sub) chronic administration. In day to day practice besides acute drug response, often a longer duration of action is desired. This situation needs the under standing of changes in pharmacokinetics of drugs upon repeated administra tion, and the dosage regimen has to be accordingly adjusted for achieving uniform therapeutic levels for desired period of time. 2 Multiple dosing The basic mathematical relationships applicable to single dose administration kinetics are also valid (with slight modifications) for multiple dose kinetics. In multiple dose therapy the ultimate purpose is to achieve a steady drug effect or response with minimum side effects. As mentioned before, this can be achieved in most cases by maintaining the plasma concentrations in therapeutic range for required number of hours or days. This may be considered as a general rule with an exception of nitrates, in which case the concentrations during the interval between two doses (called "dosing interval") should fall below a critical threshold level, such that tolerance does not develop. A drug is commonly administered in fixed doses at constant intervals of time so that the amount lost through elimination is replaced after each dose.
Clinical Pharmacokinetics
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Author : John E. Murphy
language : en
Publisher: ASHP
Release Date : 2011-10-01
Clinical Pharmacokinetics written by John E. Murphy and has been published by ASHP this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-01 with Medical categories.
In the complex field of pharmacokinetics, one reference guide has an identity all its own: Clinical Pharmacokinetics. Now the fully updated 5th edition brings to experienced practitioners and students alike the fresh information they need most: · Content organized for fast reference to specific drugs · The latest on dosing in obese and overweight patients · Dosing considerations for neonatal, pediatric and geriatric patients · A look at protein binding and its implications · Population values for a variety of drugs to initiate dosing · Drug dosing in renal disease and creatinine clearance estimation A Distinctively Straightforward Guide is Now Even Better The 5th Edition of Clinical Pharmacokinetics is completely revised and updated, making a handy clinical guide even easier to use than ever. · Reorganized content features two sections: Basic Concepts and Special Populations and Specific Drugs and Drug Classes · Sections on special populations, including Dosing in Overweight and Obese Patients, have been conveniently grouped together · Comprehensive introduction covers means, measurements and monitoring · Also conveniently placed up front” a glossary of pharmacokinetics basics and commonly used equations
Biopharmaceutics And Clinical Pharmacokinetics
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Author : Notari
language : en
Publisher: Routledge
Release Date : 2017-11-22
Biopharmaceutics And Clinical Pharmacokinetics written by Notari and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Science categories.
For a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics. Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses. Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics. As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.
Concepts In Clinical Pharmacokinetics
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Author : Joseph T. DiPiro
language : en
Publisher: ASHP
Release Date : 2010
Concepts In Clinical Pharmacokinetics written by Joseph T. DiPiro and has been published by ASHP this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Short Description: This popular teaching and self-instructional text makes it easier than ever to acquire a strong foundation in the basic principles of pharmacokinetics.
Drug Metabolism And Pharmacokinetics Quick Guide
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Author : Siamak Cyrus Khojasteh
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-04-07
Drug Metabolism And Pharmacokinetics Quick Guide written by Siamak Cyrus Khojasteh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-07 with Medical categories.
Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.
Biopharmaceutics And Clinical Pharmacokinetics
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Author : Robert E. Notari
language : en
Publisher:
Release Date : 1980
Biopharmaceutics And Clinical Pharmacokinetics written by Robert E. Notari and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Biopharmaceutics categories.
Pharmacokinetics A Beginner S Guide
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Author : John Kolthammer
language : en
Publisher: Inst of Clinical Research
Release Date : 2007
Pharmacokinetics A Beginner S Guide written by John Kolthammer and has been published by Inst of Clinical Research this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Pharmacokinetics categories.
Everything you ever wanted to know about basic pharmacokinetics.