Advances In Multiple Sclerosis Research Mdash Series I
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Advances In Multiple Sclerosis Research Mdash Series I
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Author : John Matsoukas
language : en
Publisher: MDPI
Release Date : 2021-04-19
Advances In Multiple Sclerosis Research Mdash Series I written by John Matsoukas and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-19 with Science categories.
Designing immunotherapeutics, drugs, and anti-inflammatory reagents has been at the forefront of autoimmune research, in particular multiple sclerosis, for over 20 years. Delivery methods that are used to modulate effective and long-lasting immune responses have been the major focus. This Special Issue focused on delivery methods to be used for vaccines, immunotherapeutic approaches, drug design, and anti-inflammatories and their outcomes in preclinical studies and clinical trials.
Advances In Multiple Sclerosis Research Series I
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Author : John Matsoukas
language : en
Publisher:
Release Date : 2021
Advances In Multiple Sclerosis Research Series I written by John Matsoukas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Designing immunotherapeutics, drugs, and anti-inflammatory reagents has been at the forefront of autoimmune research, in particular multiple sclerosis, for over 20 years. Delivery methods that are used to modulate effective and long-lasting immune responses have been the major focus. This Special Issue focused on delivery methods to be used for vaccines, immunotherapeutic approaches, drug design, and anti-inflammatories and their outcomes in preclinical studies and clinical trials.
Powder Injection Molding
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Author : Randall M. German
language : en
Publisher:
Release Date : 2003
Powder Injection Molding written by Randall M. German and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Technology & Engineering categories.
Mcalpine S Multiple Sclerosis
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Author : Alastair Compston
language : en
Publisher:
Release Date : 1998
Mcalpine S Multiple Sclerosis written by Alastair Compston and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development.
Combination Therapy In Ms
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Author : Yvette Corinne Zwick
language : en
Publisher: Schattauer Verlag
Release Date : 2005
Combination Therapy In Ms written by Yvette Corinne Zwick and has been published by Schattauer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Spectrums Of Amyotrophic Lateral Sclerosis
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Author : Christopher A. Shaw
language : en
Publisher: John Wiley & Sons
Release Date : 2021-04-20
Spectrums Of Amyotrophic Lateral Sclerosis written by Christopher A. Shaw and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-20 with Medical categories.
SPECTRUMS OF AMYOTROPHIC LATERAL SCLEROSIS Discover state-of-the-art research findings on ALS from leading authors and editors in the field In Spectrums of Amyotrophic Lateral Sclerosis: Heterogeneity, Pathogenesis & Therapeutic Directions, distinguished researchers and editors Dr. Christopher A. Shaw and Jessica R. Morrice deliver a practical and powerful perspective on Amyotrophic Lateral Sclerosis (ALS) as a heterogeneous spectrum of disorders. This increasingly accepted point-of-view allows researchers and medical professionals to develop better targeted interventions and more precise therapies. In the book, readers will find chapters on a wide variety of critical issues facing ALS researchers and healthcare practitioners treating ALS sufferers, including animal models of ALS, neuronal support cells known to have a pivotal role in ALS, and current challenges in ALS clinical trials, among others. The authors describe pathologic features common to all cases of ALS and why animal models, though crucial, should be interpreted with caution. Finally, multiple genetic and environmental etiologies of the disease are discussed. Readers will also benefit from the inclusion of: A thorough introduction to ALS as a spectrum disease and the implications for models, therapeutic development and clinical trial design Explorations of the genetic basis of ALS, prospective sALS etiologies, and the involvement of microbiome in ALS Discussions of ALS-PDC and environmental risk factors, protein aggregation in ALS, defects in RNA metabolism in ALS, and the non-cell autonomous nature of ALS and the involvement of glial cells Examinations of animal models of ALS and perspectives on previously failed ALS therapeutics and current therapeutic strategies Perfect for clinical neurologists, healthcare providers and caretakers, clinicians, and researchers studying motor neuron disease, Spectrums of Amyotrophic Lateral Sclerosis: Heterogeneity, Pathogenesis & Therapeutic Directions is also an indispensable resource for the neurodegenerative research community, neurology residents, and graduate-level neuroscience students.
Recent Advancement In Prodrugs
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Author : Kamal Shah
language : en
Publisher: CRC Press
Release Date : 2020-05-13
Recent Advancement In Prodrugs written by Kamal Shah and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-13 with Science categories.
Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.
Innovations For Next Generation Antibody Drug Conjugates
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Author : Marc Damelin
language : en
Publisher: Springer
Release Date : 2018-05-29
Innovations For Next Generation Antibody Drug Conjugates written by Marc Damelin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-29 with Medical categories.
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
Recent Advances In Organocatalysis
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Author : Iyad Karamé
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-09-28
Recent Advances In Organocatalysis written by Iyad Karamé and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-28 with Science categories.
Organocatalysis has recently attracted enormous attention as green and sustainable catalysis. It was realized as a fundamental field providing wide families of catalysts for important organic transformations. It will certainly develop in the future. Given the diversity of accessible transformations, metal-catalyzed reactions have become major tools in organic synthesis that will undoubtedly continue to have an important impact in the future. Alternatively, over the last years, a metal-free approach such as organocatalysis has reached a level of faithfulness, allowing researchers to discover new catalytic systems based on engagement of new or early-prepared organic molecules as organocatalysts. Organocatalysis meets green chemistry principles, especially the reduction of toxicity and chemical accidents, the biodegradability, and the use of benign and friendlier reaction media and conditions.
Intelligent Energy Management Technologies
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Author : Mohammad Shorif Uddin
language : en
Publisher: Springer Nature
Release Date : 2020-12-01
Intelligent Energy Management Technologies written by Mohammad Shorif Uddin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-01 with Technology & Engineering categories.
This book is a collection of best selected high-quality research papers presented at the International Conference on Advances in Energy Management (ICAEM 2019) organized by the Department of Electrical Engineering, Jodhpur Institute of Engineering & Technology (JIET), Jodhpur, India, during 20–21 December 2019. The book discusses intelligent energy management technologies which are cost effective compared to the high cost of fossil fuels. This book also explains why these systems have beneficial impact on environmental, economic and political issues of the world. The book is immensely useful for research scholars, academicians, R&D institutions, practicing engineers and managers from industry.
