All Aqueous Multiphase Microfl
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All Aqueous Multiphase Microfl
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Author : Yang Song
language : en
Publisher: Open Dissertation Press
Release Date : 2017-01-26
All Aqueous Multiphase Microfl written by Yang Song and has been published by Open Dissertation Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-26 with Technology & Engineering categories.
This dissertation, "All-aqueous Multiphase Microfluidics: From Formation of Liquid Structures to Synthesis of Biomaterials" by Yang, Song, 宋阳, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Droplet microfluidics which enables manipulation on droplets has been widely applied in the production of cosmetics and medicine, fabrication of materials, and bioassays. To form emulsion droplets, organic solvents are frequently used as oil phases. Nevertheless, the use of organic solvents also causes concerns on the biocompatibility and health issues due to their toxicity. In particular, the interface formed by water and oil can cause the denaturation of proteins and even death of cells. Therefore, an alternative set of emulsion droplets without the using of organic solvents is demanded in biomedical applications. In the first chapter of this dissertation, we present an all-aqueous microfluidic approach to generate emulsion droplets from immiscible aqueous phases. Such immiscible aqueous phases take advantages of the phase separation between the incompatible solutes dissolved in water to form all-aqueous emulsions. Compared to the water/oil emulsion systems, the all-aqueous emulsion is advantageous in processing of biomolecules and cells. However, manipulation on the structure of the all-aqueous emulsion is challenged by the ultralow interfacial tension between two immiscible aqueous phases. In the second chapter, we demonstrate the ability to control the structure of the all-aqueous emulsions by combining a perturbation approach and a phase-separation approach. Nevertheless, this approach is only applicable to non-viscous w/w systems. In particular, when biomolecules such as protein and polysaccharide are dissolved to form a viscous mixture, the resultant fluids are often too viscous to be handled by this approach. Alternatively, we investigate using an applied electrical field to manipulate the liquid structures of viscous aqueous phases in chapter 3 and 4. In chapter 3, we present a technique of controlling the folding and unfolding of viscous water-in-water (w/w) jet in the microfluidic channels by electrical charging. In chapter 4, we introduce an all-aqueous electrospray approach to generate w/w droplets from viscous aqueous phases. By using the all-aqueous emulsion droplets as templates, hydrogel particles and core-shell structured capsules can be fabricated with highly tunable structures. The fabricated particles and capsules exhibit good cytocompatibility, which can be used for delivery of bioactive proteins (Chapter 5). However, without the gelation of w/w emulsion droplets, interface of the w/w emulsion are intrinsically unstable. Therefore, we investigate the stabilization of w/w emulsion droplets by using protein nanofibrils with high aspect ratios in Chapter 6. These protein nanofibrils can be efficiently adsorb to the w/w interface and stabilize the w/w droplets. The stabilized droplets can be further used for fabrication of robust protein vesicles. When the concentration of protein fibrils is further increased, a colloidal network forms inside the w/w droplets. Such a composite structure exhibits interesting budding and splitting behaviors upon osmotic shrinking, suggesting the possibility of fabricating functionalized biomaterials by using all-aqueous emulsion droplets as templates. In summary, an all-aqueous multiphase microfluidic technology is developed in this dissertation. This technology enables the manipulation of all-aqueous structures, which provides a versatile and biocompatible platform for fabrication of biomaterials.
All Aqueous Multiphase Microfluidics
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Author : 宋阳
language : en
Publisher:
Release Date : 2015
All Aqueous Multiphase Microfluidics written by 宋阳 and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Microfluidics categories.
Multiphase Microfluidics The Diffuse Interface Model
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Author : Roberto Mauri
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-05-31
Multiphase Microfluidics The Diffuse Interface Model written by Roberto Mauri and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-31 with Science categories.
Diffuse interface (D.I.) model for muliphase flows.- Phase separation of viscous ternary liquid mixtures.- Dewetting and decomposing films of simple and complex liquids.- Phase-field models. Multiphase flows are typically described assuming that the different phases are separated by a sharp interface, with appropriate boundary conditions. This approach breaks down whenever the lengthscale of the phenomenon that is being studied is comparable with the real interface thickness, as it happens, for example, in the coalescence and breakup of bubbles and drops, the wetting and dewetting of solid surfaces and, in general, im micro-devices. The diffuse interface model resolves these problems by assuming that all quantities can vary continuously, so that interfaces have a non-zero thickness, i.e. they are "diffuse". The contributions in this book review the theory and describe some relevant applications of the diffuse interface model for one-component, two-phase fluids and for liquid binary mixtures, to model multiphase flows in confined geometries.
Microfluidics Enabled Soft Manufacture
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Author : Pingan Zhu
language : en
Publisher: Springer Nature
Release Date : 2022-03-11
Microfluidics Enabled Soft Manufacture written by Pingan Zhu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-11 with Science categories.
This book covers state-of-the-art development in microfluidics-enabled soft manufacturing (MESM), ranging from fundamentals to applications. The book addresses the long-standing challenge in the manufacture of simultaneously achieving both precise control over nano-/micro-scale structures and large-scale fabrication of materials for pragmatic use, with microfluidics-enabled soft manufacture to fill the gap between the widely-varied length scales involved. It offers a comprehensive insight into the microfluidic generation of fluid systems as liquid templates, such as droplets, bubbles, jets, emulsions, and foams, which are categorized into individual templates, one-dimensional arrays, and two-/three-dimensional assemblies for the modular fabrication of microparticles, microfibers, and porous materials, respectively. MESM enriches the compositional and structural diversity of engineered materials for well-tailored properties and functionalities, markedly broadening the application horizons across interdisciplinary fields, including engineering, environment, physics, chemistry, biology, and medicine. This book aims to systematize this emerging yet versatile and powerful technology, with the hope of aiding the realization of its full potential. Microfluidics-Enabled Soft Manufacture will be an invaluable reference for graduate students, postgraduates, researchers, and practitioners/professionals working in micro and nanofabrication, materials science, surface science, fluid dynamics, and engineering.
Multiphase Microfluidics On A Centrifugal Platform
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Author : Stefan Häberle
language : en
Publisher:
Release Date : 2008
Multiphase Microfluidics On A Centrifugal Platform written by Stefan Häberle and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Advances In Microfluidics
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Author : Xiao-Ying Yu
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-11-23
Advances In Microfluidics written by Xiao-Ying Yu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-23 with Science categories.
Increasing innovations and applications make microfluidics a versatile choice for researchers in many disciplines. This book consists of multiple review chapters that aim to cover recent advances and new applications of microfluidics in biology, electronics, energy, and materials sciences. It provides comprehensive views of various aspects of microfluidics ranging from fundamentals of fabrication, flow control, and droplet manipulation to the most recent exploration in emerging areas such as material synthesis, imaging and novel spectroscopy, and marriage with electronics. The chapters have many illustrations showcasing exciting results. This book should be useful for those who are eager to learn more about microfluidics as well as researchers who want to pick up new concepts and developments in this fast-growing field.
Principles Of Multiple Liquid Separation Systems
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Author : Kit Wayne Chew
language : en
Publisher: Elsevier
Release Date : 2023-01-12
Principles Of Multiple Liquid Separation Systems written by Kit Wayne Chew and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-12 with Technology & Engineering categories.
Principles of Multiple-Liquid Separation Systems: Interaction, Application and Advancement describes the basic principles and advancements of multiple-liquid separation systems in downstream processing. Several important elements are included, such as the fundamental process and mechanisms of the multiple-liquid separation system, key principles of the interaction between different solvents and phase components, applications, and green solvents for the separation system. Furthermore, the book gives insights in commercializing this separation technique to industrial scale and making the process environmentally and economically sustainable. The book also presents constructive critics of this separation technique for both past and the latest findings. Comprehensively reviews several advanced separation methods and their fundamentals in a single source Covers a deep understanding of the interaction between various liquid phase techniques and the latest cases of advanced techniques applied in bioprocesses Provides a critical and constructive judgement of costs and environmental sustainability of multiple-liquid separation systems
Microfluidics For Advanced Functional Polymeric Materials
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Author : Liang-Yin Chu
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-13
Microfluidics For Advanced Functional Polymeric Materials written by Liang-Yin Chu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-13 with Technology & Engineering categories.
A comprehensive and systematic treatment of our current understanding of the microfluidic technique and its advantages in the controllable fabrication of advanced functional polymeric materials. Introducing and summarizing recent advances and achievements in the field, the authors cover the design and fabrication of microfluidic devices, the fundamentals and strategies for controllable microfluidic generation of multiphase liquid systems, and the use of these liquid systems with an elaborate combination of their structures and compositions for generating novel polymer materials, such as microcapsules, microfibers, valves, and membranes. Clear diagrams and illustrations throughout the text make the relevant theory and technologies more readily accessible. The result is a specialist reference for materials scientists, organic, polymer and physical chemists, and chemical engineers.
New And Future Developments In Microbial Biotechnology And Bioengineering
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Author : Harikesh Bahadur Singh
language : en
Publisher: Elsevier
Release Date : 2022-02-03
New And Future Developments In Microbial Biotechnology And Bioengineering written by Harikesh Bahadur Singh and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-03 with Technology & Engineering categories.
New and Future Developments in Microbial Biotechnology and Bioengineering: Sustainable Agriculture: Advances in Microbe-Based Biostimulants describes advances in microbial mechanisms involved in crop production and stress alleviation. Recent developments in our understanding of the role of microbes in sustainable agriculture and disease management have created a highly potential research area. The plant holobiont has a significant role in stress signaling, nutrient use efficiency, and soil health and fertility for sustainable developments. The mycorrhizosphere, hyphosphere, phyllosphere, rhizosphere and endosphere are critical interfaces for the exchange of signaling and resources between plants and soil environment.? This book is an ideal reference source for microbiologists, agrochemists, biotechnologists, biochemists, industrialists, researchers and scientists working on agriculturally important microorganisms and their exploitation in sustainable future applications. Gives insights into mechanisms of plant-microbe interaction Introduces new aspects and advances in plant-microbe interaction for disease management Includes descriptions and modern practices on how to harness the potential of microbes in sustainable agriculture applications
Advances In Biomembranes And Lipid Self Assembly
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Author : Ales Iglic
language : en
Publisher: Academic Press
Release Date : 2019-03-26
Advances In Biomembranes And Lipid Self Assembly written by Ales Iglic and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-26 with Science categories.
Advances in Biomembranes and Lipid Self-Assembly, Volume 29, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale. As planar lipid bilayers are widely studied due to their ubiquity in nature, this book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers. Surveys recent theoretical and experimental results on lipid micro- and nanostructures Presents potential use applications, such as clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering and food products Includes both original research and comprehensive reviews written by world leading experts and young researchers Provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale