American Trypanosomiasis Chagas Disease
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American Trypanosomiasis
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Author : Jenny Telleria
language : en
Publisher: Elsevier
Release Date : 2010-09-03
American Trypanosomiasis written by Jenny Telleria and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-03 with Medical categories.
Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: The host: human and mammalian reservoirs The insect vectors: domestic and sylvatic vectors The causative parasite: Trypanosoma cruzi Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts
American Trypanosomiasis
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Author : Kevin M. Tyler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
American Trypanosomiasis written by Kevin M. Tyler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
American trypanosomiasis, or Chagas disease, is caused by the protozoan parasite, Trypanosoma cruzi. Sixteen to eighteen million people are currently infected with this organism, and 45,000 deaths are attributed to the disease each year. Infection with T. cruzi is life-long, and 10-30% of persons who harbor the parasite chronically develop cardiac and gastrointestinal problems associated with the parasitosis. Although major progress has been made in recent years in reducing vector-borne and transfusion-associated transmission of T. cruzi, the burden of disability and death in persons chronically infected with the organism continues to be enormous. Eight to ten million persons born in countries in which Chagas disease is endemic currently reside in the United States, and epidemiologic and census data suggest that 50,000-100,000 are chronically infected with T. cruzi. The presence of these infected persons poses a risk of transmission of the parasite in the USA through blood transfusion and organ transplantation and several such cases have now been documented. American Trypanosomiasis, volume seven of World Class Parasites is written for students of tropical medicine, parasitology and public health, for researchers and practitioners alike who wish to bring themselves abreast of the status quo with respect to this disease. It is intended to supplement formal textbooks, in order to broaden and illuminate current areas of scientific and public health concern. Uniquely for T. cruzi, this book addresses parasite, vector and host biology, the pathogenesis of Chagas disease and current and prospective therapeutics and control strategies in a single volume.
Chagas Disease
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Author : María-Jesús Pinazo Delgado
language : en
Publisher: Springer Nature
Release Date : 2020-07-20
Chagas Disease written by María-Jesús Pinazo Delgado and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-20 with Medical categories.
This book provides a comprehensive resource on various aspects of the parasite Trypanosoma cruzi and the neglected tropical disease Chagas disease (American trypanosomiasis), the disorder resulting from infection with the parasite. Topics include the biological description and taxonomy of the parasite, epidemiology and transmission routes, laboratory techniques in use when working with the parasite, as well as diagnostic measures and treatment of Chagas disease. Furthermore, a chapter with life stories of people in contact with the disease in endemic as well as non-endemic countries is included. The book is therefore a valuable source for individuals engaged in basic research as well as patient care and health management related to American trypanosomiasis.
Historical Aspects Of American Trypanosomiasis Chagas Disease
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Author : Matthias Perleth
language : en
Publisher: Peter Lang Pub Incorporated
Release Date : 1997-01-01
Historical Aspects Of American Trypanosomiasis Chagas Disease written by Matthias Perleth and has been published by Peter Lang Pub Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-01 with Medical categories.
Chagas Disease
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Author :
language : en
Publisher:
Release Date : 1992
Chagas Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with categories.
Trypanosoma Cruzi As A Foodborne Pathogen
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Author : Belkisyolé de Noya
language : en
Publisher: Springer
Release Date : 2015-10-29
Trypanosoma Cruzi As A Foodborne Pathogen written by Belkisyolé de Noya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-29 with Technology & Engineering categories.
This Brief provides a comprehensive overview of Trypanosoma cruzi, a parasite that is traditionally considered as exclusively vectorborne, but can be foodborne, and may lead to outbreaks of Chagas disease in consumers. The characteristics of Trypanosoma cruzi and the clinical effects of the disease are covered, including documented outbreaks, regional patterns, and epidemiology. The various transmission routes are outlined, but with specific focus on foodborne transmission. A major emphasis of this text is contamination of fruit juices with Trypanosoma cruzi in, a transmission vehicle with increasing significance in the spread of this parasite. Also outlined is the difficulty of establishing a protocol for detection in food samples. Results on survival of Trypanosoma cruzi in food matrices is considered, as well as current risk assessment procedures and regulations. Different approaches to preventing transmission, including inactivation and decontamination are introduced, but also the importance of targeted educational initiatives, and also with a focus on future detection, prevention, and prevention of contamination of foods with this parasite.
Chagas Disease
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Author : Sandra R. Wall
language : en
Publisher: Nova Biomedical Books
Release Date : 2017
Chagas Disease written by Sandra R. Wall and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Chagas' disease categories.
The authors begin reviewing the characterization of American trypanosomiasis, or Chagas Disease, noting that although the disease has become less prevalent in recent decades, it is estimated that 8-10 million people are currently infected. Next, authors present a study wherein the dynamics of Trypanosoma cruzi infection (which causes Chagas disease) were mathematically modelled. This model assumed three clinical stages of the disease; acute, chronic indeterminate, and chronic with determinate pathology. Following this, cysteine proteases, ergosterol metabolic pathways, thiol-dependent mechanisms (trypanothione reductase), glycolytic pathways, trans-sialidase enzymes, the transport and metabolism of polyamines, and examples from literature are described in the context of therapeutic targets. The book goes on to discuss the history of nifurtimox and benznidazole, two drugs used in an effort combat Chagas disease. Additionally, the chapter addresses new therapies in clinical research to develop new treatments for Chagas' disease. In closing, the authors discuss the idea of targeting the cell cycle of T. cruzi in chemotherapy because the parasite undergoes several morphological changes to adapt to its vertebrate and invertebrate hosts.
Chagas Disease
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Author : Veeranoot Nissapatorn
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-09-12
Chagas Disease written by Veeranoot Nissapatorn and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-12 with Medical categories.
This book contains 11 chapters of significant and updated materials on what we know and what we lack and need in better understanding of Trypanosoma cruzi - a parasite that never dies - and the consequences of Chagas disease as one of the most important neglected parasitic diseases threatening the global health and wellbeing. This book is intended to increase the readers' enthusiasm to explore the four sections of the contents: Section 1 begins with biochemistry, pathophysiology, histo-immunological study, and findings to assist in the diagnosis; Section 2 further investigates the role of vector in propagation of the parasite, the intensity on epidemiology, and the severity on clinical aspects, which help us to be well perceived on the course of disease; Section 3 is seeking beyond modern medicine and what lays in the nature that helps fight against this parasite; and the last section, Section 4, deals with the impacts of public health problem and the control strategies on Chagas disease.
Chagas Disease
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Author : Jaime Marcelo Altcheh
language : en
Publisher: Springer Nature
Release Date : 2019-09-09
Chagas Disease written by Jaime Marcelo Altcheh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-09 with Science categories.
Chagas disease is a potentially life threatening condition that was historically mainly endemic to Latin America. Over the last decade, however, the disease has spread to and is increasingly prevalent in other continents such as North America and Europe, with an estimated 7 million people infected worldwide. It is primarily transmitted by insect vectors that carry the parasite Trypanosoma cruzi, the disease agent. In areas where there is vector control and in non-endemic countries, it is mainly transmitted via congenital infection. Cardiac and gastrointestinal complications are common in untreated individuals. This book offers a comprehensive overview of Chagas disease, including its vectorial and congenital transmission, and molecular diagnosis, which is essential for screening, and developing and providing timely, effective anti-trypanosomal treatment. Written by experts working with infected patients on a daily basis, it discusses the pathogenesis of congenital, cardiac, gastrointestinal and oral Chagas disease, as well as its treatment and the pharmacological aspects of drug development in this area. Chapter "Chagas Disease Treatment Efficacy Biomarkers: Myths and Realities" is available open access under a via link.springer.com.
American Trypanosomiasis Chagas Disease
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Author : C.A. Santos-Buch
language : en
Publisher:
Release Date : 1979
American Trypanosomiasis Chagas Disease written by C.A. Santos-Buch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with categories.