Anti Sars Cov 2 Activity Of Flavonoids
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Anti Sars Cov 2 Activity Of Flavonoids
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Author : Jen-Tsung Chen
language : en
Publisher: CRC Press
Release Date : 2024-07-16
Anti Sars Cov 2 Activity Of Flavonoids written by Jen-Tsung Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-16 with Medical categories.
In the past years, COVID-19 caused millions of deaths and severely damaged not only public health, but also the global economy. New variants continue to threaten human health. Thus, natural compounds for retarding infection are in high demand. This book summarizes the emerging research with flavonoids, whose application holds great promise of antivirus, anti-inflammation, antioxidative stress, and immunomodulatory. Topics include the role of flavonoids in preventing an inflammatory storm and how flavonoids interact with critical protein targets that are involved in the infection stages of COVID-19. Key Features • Highlights anti-SARS-CoV-2 drug discovery on natural products and medicinal plants • Includes all major subclasses of flavonoids that promisingly combat COVID-19 • Proposes molecular mechanisms of flavonoids against protein targets of SARS-CoV-2 • Contributions from an international team of leading researchers • Provides recommendations with respect to the future research
Ethnopharmacology And Drug Discovery For Covid 19 Anti Sars Cov 2 Agents From Herbal Medicines And Natural Products
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Author : Jen-Tsung Chen
language : en
Publisher: Springer Nature
Release Date : 2023-10-09
Ethnopharmacology And Drug Discovery For Covid 19 Anti Sars Cov 2 Agents From Herbal Medicines And Natural Products written by Jen-Tsung Chen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-09 with Medical categories.
This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
Flavonoids As Nutraceuticals
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Author : Rajesh K. Kesharwani
language : en
Publisher: CRC Press
Release Date : 2024-04-09
Flavonoids As Nutraceuticals written by Rajesh K. Kesharwani and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-09 with Medical categories.
Flavonoids are well-known plant metabolites that have extraordinary properties that can be used for treating health issues. The pharmaceutical importance of flavonoids is due to their anti-depressant, anti-viral, anti-inflammatory, and antioxidant capacities. They are also of great importance when it comes to neuroprotection, cardiovascular disorders, and many types of cancer. Flavonoids are also easily available and produce less harmful side effects than some conventional therapeutics. This new volume examines the growing use of flavonoids for prevention and treatment of diseases and discusses their beneficial mechanisms. Chapters in the volume address diverse uses as anti-aging tools, as anti-inflammatory agents, for treating pregnancy-induced disorders, as a promising tool to combat infection of Covid-19, etc. The book explores their specific therapeutic antiviral potentials, the gene expression by flavonoids, and the role of flavonoids in agriculture.
Flavonoids And Their Disease Prevention And Treatment Potential
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Author : H.P. Vasantha Rupasinghe
language : en
Publisher: MDPI
Release Date : 2021-03-29
Flavonoids And Their Disease Prevention And Treatment Potential written by H.P. Vasantha Rupasinghe and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-29 with Science categories.
Flavonoids are ubiquitously present in plant-based foods and natural health products. The molecule of flavonoids is characterized by a 15-carbon skeleton of C6–C3–C6, with the different structural configuration of subclasses. The major subclasses of flavonoids with health-promotional properties are the flavanols or catechins (e.g., epigallocatechin 3-gallate from green tea), the flavones (e.g., apigenin from celery), the flavonols (e.g., quercetin glycosides from apples, berries, and onion), the flavanones (e.g., naringenin from citrus), the anthocyanins (e.g., cyanidin-3-O-glucoside from berries), and the isoflavones (e.g., genistein from soya beans). Scientific evidence has strongly shown that regular intake of dietary flavonoids in efficacious amounts reduces the risk of oxidative stress- and chronic inflammation-mediated pathogenesis of human diseases such as cardiovascular disease, certain cancers, and neurological disorders. The physiological benefits of dietary flavonoids have been demonstrated to be due to multiple mechanisms of action, including regulating redox homeostasis, epigenetic regulations, activation of survival genes and signaling pathways, regulation of mitochondrial function and bioenergetics, and modulation of inflammation response. The role of flavonoids on gut microbiota and the impact of microbial metabolites of flavonoids on optimal health has begun to unravel. The complex physiological modulations of flavonoid molecules are due to their structural diversity. However, some flavonoids are not absorbed well, and their bioavailability could be enhanced through structural modifications and applications of nanotechnology, such as encapsulation. This Special Issue consists of four review articles on flavonoids and 15 original research articles, which cover the latest findings on the role of dietary flavonoids and their derivatives in disease prevention and treatment.
Plant Natural Products For Human Health
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Author : Chun-Tao Che
language : en
Publisher: MDPI
Release Date : 2019-03-21
Plant Natural Products For Human Health written by Chun-Tao Che and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-21 with Social Science categories.
Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs for human use, from morphine discovered in the early nineteenth century to the more recent paclitaxel and artemisinin. Today, we are witnessing a global resurgence in interest and use of plant-based therapies and botanical products, and natural products remain an important and viable source of lead compounds in many drug discovery programs. This Special Issue on “Plant Natural Products for Human Health” compiles a series of scientific reports to demonstrate the medicinal potentials of plant natural products. It covers a range of disease targets, such as diabetes, inflammation, cancer, neurological disease, cardiovascular disease, liver damage, bacterial, and fungus infection and malarial. These papers provide important insights into the current state of research on drug discovery and new techniques. It is hoped that this Special Issue will serve as a timely reference for researchers and scholars who are interested in the discovery of potentially useful molecules from plant sources for health-related applications.
Who Global Report On Traditional And Complementary Medicine 2019
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2019-05-16
Who Global Report On Traditional And Complementary Medicine 2019 written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-16 with Business & Economics categories.
This report is structured in five parts: national framework for traditional and complementary medicine (T&CM); product regulation; practices and practitioners; the challenges faced by countries; and finally the country profiles. Apart from the section on practices and practitioners the report is consistent with the format of the report of the first global survey in order to provide a useful comparison. The section on practices and practitioners which covers providers education and health insurance is a new section incorporated to reflect the emerging trends in T&CM and to gather new information regarding these topics at a national level. All new information received has been incorporated into individual country profiles and data graphs. The report captures the three phases of progress made by Member States; that is before and after the first WHO Traditional Medicine Strategy (1999?2005) from the first global survey to the second global survey (2005?2012) and from the second survey to the most recent timeline (2012?2018).
Inhibition Of Epstein Barr Virus Reactivation By The Flavonoid Apigenin
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Author : Oceanside Oceanside Press
language : en
Publisher:
Release Date : 2017-07-27
Inhibition Of Epstein Barr Virus Reactivation By The Flavonoid Apigenin written by Oceanside Oceanside Press and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-27 with categories.
Lytic reactivation of EBV has been reported to play an important role in human diseases, including NPC carcinogenesis. Inhibition of EBV reactivation is considered to be of great benefit in the treatment of virus-associated diseases. For this purpose, we screened for inhibitory compounds and found that apigenin, a flavonoid, seemed to have the ability to inhibit EBV reactivation. Proceeds from the sale of this book go to support an elderly disabled person.
Citrus In Mexico
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Author : Edmond Missiaen
language : en
Publisher:
Release Date : 1981
Citrus In Mexico written by Edmond Missiaen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Agriculture categories.
Bioactive Compounds Against Sars Cov 2
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Author : Jen-Tsung Chen
language : en
Publisher: CRC Press
Release Date : 2023-09-26
Bioactive Compounds Against Sars Cov 2 written by Jen-Tsung Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Medical categories.
Coronaviruses can cause illness, severe disease, and death; for example, Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), and COVID-19. Vaccine development and antiviral drugs are challenged by the propensity for viral mutations allowing these viruses to evade such therapies. There are a number of bioactive compounds from natural sources, which can exert health benefits and act as antiviral therapies such as anti-inflammation, antioxidative stress, and immune regulation. This book summarizes research on the potential efficacy and underlying mechanisms of bioactive compounds and traditional medicines against SARS-CoV-2. Key Features Summarizes the potential benefits of bioactive therapies for coronaviruses Focuses on COVID-19, but also covers MERS and SARS Provides alternatives to vaccines and other antiviral drugs whose efficacy is reduced by viral mutations Relevant for clinicians and public health officials
Natural Products In Clinical Trials
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Author : Atta-ur- Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2018-03-03
Natural Products In Clinical Trials written by Atta-ur- Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-03 with Medical categories.
Natural products continue to play a key role in drug development. A recent analysis of the drug market in the developed world revealed that 40% of total clinically approved drugs were either unmodified natural products or their semi-synthetic derivatives. This book series focuses on reviews of exciting new bioactive natural products that have huge potential as drugs. It highlights the everlasting importance of natural products in our lives. Each volume brings reviews contributed by eminent scientists in the field. The first volume covers the following topics: - bioactive compounds from marine invertebrates - natural product derived drugs for immunological and inflammatory diseases - clinical trials of curcumin, camptothecin, astaxanthin, and biochanin - antibacterial and antifungal drugs from natural sources - natural products as anti-HIV medicines.