Antifibrinolytic Drugs
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Antifibrinolytic Drugs
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Author : Derek Ogston
language : en
Publisher: John Wiley & Sons
Release Date : 1984
Antifibrinolytic Drugs written by Derek Ogston and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medical categories.
Antifibrinolytic Drugs
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Author : Derek Ogston
language : en
Publisher:
Release Date :
Antifibrinolytic Drugs written by Derek Ogston and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Fibrinolytics And Antifibrinolytics
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Author : Fritz Markwardt
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Fibrinolytics And Antifibrinolytics written by Fritz Markwardt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Disturbances of haemostasis and thromboembolic disorders still constitute a great problem in clinical practice. Increasing insight into the mechanism of blood coagula tion has led to more effective therapy and prophylaxis. Particularly, the understand ing of the biochemistry of fibrinolysis has provided possibilities for the pharma cological interference of these processes, which has resulted in effective haemostatic agents and useful antithrombotic ones. The development of antifibrinolytics for interfering with pathological fibrinolytic processes is nearly complete and has led to the development of drugs essential to the therapy of hyperfibrinolytic bleeding. The search for fibrinolytics for dissolving intravascular thrombi has led to highly effective compounds. This development is still under way and promising results are hoped. Spontaneous dissolution of blood clots is a phenomenon which was described a century ago. First investigations of this process assured that there is in the organism a system capable of removing the fibrin which is formed during blood coagulation after it has fulfilled its physiological function. This fibrinolytic system is specifically adapted to the degradation of insoluble fibrin into soluble degradation products. In the past 30 years, thorough investigation of this system has clarified the fibrinolytic process, its physiological role and its meaning as a pathogenetic principle. A good knowledge of these processes is required for an understanding of the effects and side effects of fibrinolytics and antifibrinolytics, which comprise the basis of methods for the detection of fibrinolytic processes in the organism and of the control of therapy with these drugs.
Fibrinolytics And Antifibrinolytics
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Author : Birger Blombäck
language : en
Publisher: Springer
Release Date : 1978
Fibrinolytics And Antifibrinolytics written by Birger Blombäck and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Medical categories.
Disturbances of haemostasis and thromboembolic disorders still constitute a great problem in clinical practice. Increasing insight into the mechanism of blood coagula tion has led to more effective therapy and prophylaxis. Particularly, the understand ing of the biochemistry of fibrinolysis has provided possibilities for the pharma cological interference of these processes, which has resulted in effective haemostatic agents and useful antithrombotic ones. The development of antifibrinolytics for interfering with pathological fibrinolytic processes is nearly complete and has led to the development of drugs essential to the therapy of hyperfibrinolytic bleeding. The search for fibrinolytics for dissolving intravascular thrombi has led to highly effective compounds. This development is still under way and promising results are hoped. Spontaneous dissolution of blood clots is a phenomenon which was described a century ago. First investigations of this process assured that there is in the organism a system capable of removing the fibrin which is formed during blood coagulation after it has fulfilled its physiological function. This fibrinolytic system is specifically adapted to the degradation of insoluble fibrin into soluble degradation products. In the past 30 years, thorough investigation of this system has clarified the fibrinolytic process, its physiological role and its meaning as a pathogenetic principle. A good knowledge of these processes is required for an understanding of the effects and side effects of fibrinolytics and antifibrinolytics, which comprise the basis of methods for the detection of fibrinolytic processes in the organism and of the control of therapy with these drugs.
Fibrinolytics And Antifibrinolytics
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Author : Fedor Bachmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-01-25
Fibrinolytics And Antifibrinolytics written by Fedor Bachmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-25 with Medical categories.
This book covers basic aspects of the molecular biology, biochemistry and pharmacology of the plasminogen-plasmin (fibrinolytic) system. Individual chapters, written by well-known experts in the field, are devoted to plasminogen and its activation, the tissue-type plasminogen activator (tPA), the urinary-type-plasminogen activator (uPA), inhibitors of the fibrinolytic system, and the assembly of fibrinolytic constituents on cell surfaces. The major part of the book deals with the therapeutic use of thrombolytic agents in myocardial infarction, deep venous thrombosis, pulmonary embolism, peripheral arterial occlusions and stroke. The newest thrombolytic agents are discussed in depth. Results of major clinical trials up to the end of 1999 are critically evaluated. The volume is a modern up-to-date presentation of the entire field of the treatment of arterial and venous thromboses with thrombolytic agents.
Chemical Control Of Fibrinolysis Thrombolysis
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Author : Joseph M. Schor
language : en
Publisher:
Release Date : 1970
Chemical Control Of Fibrinolysis Thrombolysis written by Joseph M. Schor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Medical categories.
Postoperative Antifibrinolytic Drugs To Control Haemorrhage
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Author : Majella Hales
language : en
Publisher:
Release Date : 2002
Postoperative Antifibrinolytic Drugs To Control Haemorrhage written by Majella Hales and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Antifibrinolytic agents categories.
Haemostasis In Cerebrospinal Fluid
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Author : P. Hindersin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Haemostasis In Cerebrospinal Fluid written by P. Hindersin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Almost a hundred years passed from the time of the first description of an intracranial aneurysm by Morgagni in 1761 to the year 1859, when Sir William Withey Gull arrived at the conclusion that haemorrhage in the subarachnoid space is caused by ruptured aneurysms. The introduction of lumbar puncture by Quincke 1891 and cerebral angiography by Moniz 1927 made it possible to establish the diagnosis of haemorrhage and its source. In recent decades the problems of treatment have come into prominence, first of all because of the inadequacy of conservative methods of treatment in most of the cases, and from surgical experience and its limitations which became apparent before very long. Because of the erratic development of neurosurgery and vascular surgery, above all, since the technique of microsurgery has been used, the entire removal of the source of haemorrhage has become a possibility, even though there were still quite different views taken regarding the most convenient time for surgical intervention, apart from the prevailing local conditions 134, 143, 144,261. In an up-to-date plan of treatment of subarachnoid haem orrhage (SAH) conservative measures are appropriate for bridging the pre-operative period, and must be considered the only solution in those cases in which the source of haemorrhage cannot be found. As far as the effectiveness of such conservative therapy is con cerned, the rate of re bleeding and the mortality provide sufficient comment.
Fibrinolysis And The Central Nervous System
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Author : Raymond Sawaya
language : en
Publisher:
Release Date : 1990
Fibrinolysis And The Central Nervous System written by Raymond Sawaya and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
The Physiological Inhibitors Of Blood Coagulation And Fibrinolysis
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Author : B. Wiman
language : en
Publisher: North-Holland
Release Date : 1979
The Physiological Inhibitors Of Blood Coagulation And Fibrinolysis written by B. Wiman and has been published by North-Holland this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.