Antitumor Drug Radiation Interactions

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Antitumor Drug Radiation Interactions

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Author : Bridget T. Hill
language : en
Publisher: CRC Press
Release Date : 2018-01-10

Antitumor Drug Radiation Interactions written by Bridget T. Hill and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-10 with Medical categories.

This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation combinations. It includes discussions on the relative merits of experimental data derived from animal versus human tumors. This book also presents a section on the potential for new model systems or alternative test procedures for evaluating therapeutic benefits and cytotoxicities. Results of randomized clinical studies are reviewed with emphasis on recent studies involving protocols specifically designed to test the benefits from optimal integration of chemotherapy with radiotherapy. This book is intended for laboratory researchers in the field and clinicians interested in using the combined modality approach. It is also a useful resource for radiologists, oncologists, and all those interested in cancer research.

Antitumor Drug Radiation Interactions

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Author :
language : en
Publisher:
Release Date : 2017

Antitumor Drug Radiation Interactions written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Electronic book categories.

Interaction Of Radiation And Antitumor Drugs

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Author :
language : en
Publisher:
Release Date : 1976

Interaction Of Radiation And Antitumor Drugs written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Cancer categories.

Interaction Of Radiation And Antitumor Drugs

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Author : Kurt Hellmann
language : en
Publisher: Elsevier Science & Technology
Release Date : 1978

Interaction Of Radiation And Antitumor Drugs written by Kurt Hellmann and has been published by Elsevier Science & Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Cancer categories.

Radiation Drug Interactions In The Treatment Of Cancer

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Author : Gerald H. Sokol
language : en
Publisher: John Wiley & Sons
Release Date : 1980

Radiation Drug Interactions In The Treatment Of Cancer written by Gerald H. Sokol and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.

Interaction Of Radiation And Antitumor Drugs Papers Presented At The Stanford Cade Memorial Symposium

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Author :
language : en
Publisher:
Release Date :

Interaction Of Radiation And Antitumor Drugs Papers Presented At The Stanford Cade Memorial Symposium written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.

Interaction Of Radiation And Antitumor Drugs

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Author : American Society of Therapeutic Radiologists
language : en
Publisher:
Release Date : 1978

Interaction Of Radiation And Antitumor Drugs written by American Society of Therapeutic Radiologists and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.

Interaction Of Radiation And Antitumor Drugs

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Author :
language : en
Publisher:
Release Date : 1978*

Interaction Of Radiation And Antitumor Drugs written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978* with categories.

Medicinal Chemistry Of Anticancer Drugs

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Author : Carmen Avendaño
language : en
Publisher: Elsevier
Release Date : 2015-06-11

Medicinal Chemistry Of Anticancer Drugs written by Carmen Avendaño and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-11 with Science categories.

Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature

Radiation Induced Chemosensitization Potentiation Of Antitumor Activity Of Polymer Drug Conjugates

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Author :
language : en
Publisher:
Release Date : 2003

Radiation Induced Chemosensitization Potentiation Of Antitumor Activity Of Polymer Drug Conjugates written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.

This study was aimed at evaluating the enhanced antitumor response to radiotherapy by poly(L-glutamic acid)- paclitaxel (PG-TXL) conjugate. We compared the ability of paclitaxel and PG-TXL to sensitize radioresponse using both tumor growth delay and tumor curability as the end points. Furthermore, the effect of treatment schedule on the radiosensitizing activity of PG-TXL as well as the effect of PG-TXL on the sensitivity of normal tissues to radiation was also studied. Our data demonstrate significant synergistic interaction between PG-TXL and tumor radiation. Compared to paclitaxel, PG-TXL enhanced the response of tumors to radiation for approximately 4 folds. Importantly, the enhanced antitumor activity was achieved without apparent effect on the normal tissues. Our results also suggest that PG-TXL may exert its radiosensitizing effect through multiple mechanisms, one of which being sustained release of paclitaxel in the tumor from PG-TXL. This study has lead to a National Cancer Institute-sponsored clinical study that will be initiated at the University of Texas M.D. Anderson Cancer Center upon regulatory approval.