Arenaviruses Ii
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Arenaviruses Ii
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Author : M.B.A. Oldstone
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Arenaviruses Ii written by M.B.A. Oldstone and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Viruses are studied either because they cause significant human, animal or plant disease or because they are useful materials for probing basic phenomena in biology, chemistry, genetics and/or molecular biology. Arenaviruses are unusually interesting in that they occupy both categories. Arenaviruses cause several human diseases known primarily as the hemorrhagic fevers occurring in South and Latin America (Bolivia: Machupo, Argentine, Junin virus, and Brazil: Sabia virus) and in Africa (Lassa fever virus). Because such viruses produce profound disabilities and often kill the persons they infect, they are a source of health concern and economic hardship in the countries where they are prevalent. Further, they provide new problems for healthcare persons owing to the narrowing of the world as visitors from many countries travel increasingly to and from endemic areas and may incubate the infectious agent taking it from an endemic area into an area where the virus is not expected. Such cases are now being re corded with increasing frequency. In addition to these hemor rhagic fever viruses, the arenavirus lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling and severe than those elicited by the other arenaviruses. Yet, LCMV is of greater concern to non arenavirologists and experimentalists using tissue culture or ani mals, etc. , because normal-appearing cultured cells or tissues from animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and may transmit that infection to laboratory workers.
Arenaviruses I
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Author : M.B.A. Oldstone
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07
Arenaviruses I written by M.B.A. Oldstone and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.
Since the subject of arenaviruses was visited by Current Topics in Microbiology and Immunology 14 years ago, enormous advances have been made in this area. The receptor for several arenaviruses, alpha-dystroglycan, was identified, the replication strategy of these viruses was decoded, and application of a reverse genetics system for studying viral gene function and viral biology is well underway. In addition to reviewing these advances, Volume I includes discussion of arenaviral molecular phylogeny, reservoirs in rodents and clinical diseases caused by both new world and old world arenaviruses.
Arenaviruses Ii
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Author : M B a Oldstone
language : en
Publisher:
Release Date : 2002-02-26
Arenaviruses Ii written by M B a Oldstone and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-26 with categories.
The second volume of Arenaviruses deals with the biology and the pathogenesis of arenaviruses primarily through the study of LCMV. Interestingly and appropriately, the fundamental observation of MHC restriction and CD8 cytotoxic T lymphocyte killing derived initially from studies with LCMV in the mouse has been expanded to studies of most human pathogens, viral, bacterial, parasitic, as well as events in cancer. The scope and importance of this observation was recognized by awarding the Nobel Prize in 1996 to Rolf Zinkernagel and Peter Doherty, long-time workers in the field of LCMV and arenavirus biology. Over the last 14 years many of the principles for understanding viral pathogenesis and biology of animal viruses have been defined, in great part from the lessons learned by studying LCMV. Those lessons and their implications are the subject of this second volume on the arenaviruses.
Old World Arenaviruses Advances In Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Old World Arenaviruses Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Old World Arenaviruses—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Old World Arenaviruses in a compact format. The editors have built Old World Arenaviruses—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Old World Arenaviruses in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Old World Arenaviruses—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Arenaviruses
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Author : Michael B.A. Oldstone
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Arenaviruses written by Michael B.A. Oldstone and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
M. B. A. OLDSTONE Viruses are generally studied either because they cause significant human, animal or plant disease or for their utility as materials to probe a basic phenomenon in biology, chemistry, genetics or molecular biology. Arenaviruses are unusually interesting in that they occupy both of these categories. Arenaviruses cause severe human diseases known primarily as the hemor rhagic fevers occurring in South and Latin America (Bolivia: Machupo virus and Argentina: Junin virus) and in Africa (Lassa virus). Because such viruses produce profound disability and may kill the persons they infect, they are a source of economic hardship in the countries where they are prevalent. Further, they provide new problems for health care personnel owing to the narrowing of the world as visitors from many countries increasingly travel to and from these endemic areas. In addition, lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling than those elicited by other arenaviruses. Yet LCMV is likely of greater concern to non-arena-virologists and experimentalists using tissue culture or animals, i. e. , workers in molecular biology, cancer research, virology, immunobiology, etc. , because normal appearing cultured cells or tissues and animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and transmit that infection to laboratory workers (reviewed OLDSTONE and PETERS 1978). For example, HINMAN et al.
Arenaviruses
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Author : P. B. Jahrling
language : en
Publisher:
Release Date : 1985
Arenaviruses written by P. B. Jahrling and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.
The family Arenaviridae (1) is comprised of 11 or more serologically related viruses which share unique morphological and physiochemical characteristics. All arenaviruses establish chronic viremias in specific mammalian hosts (2), from which these viruses are routinely isolated (Table 1). The four arenaviruses which are pathogenic for humans were originally isolated from patients, and subsequently from the rodent reservoirs. Lymphocytic choriomeningitis virus (LCMV) was the first recognized member of the Arenaviridae and is thus considered the prototype. Originally isolated in the course of investigating a suspected St. Louis encephalitis epidemic in 1933, LCMV was soon associated with aseptic meningitis, and the further association between human disease and contact with persistently infected mice was suggested. Among the arenavirus pathogens, Junin virus was the next to be isolated, originally in 1959 from Argentina hemorrhagic fever (AHF) patients, followed by Machupo virus from Bolivian hemorrhagic fever (BHF) patients in 1963, and most recently Lassa virus from Lassa fever patients in Nigeria in 1969. The other arenaviruses listed in Table 1 have not been associated with naturally occurring human disease. Effective treatment regimens utilizing specific convalescent immune plasma and specialized antiviral drugs have been developed, and the need to improve the available diagnostic tools for rapid diagnosis of arenavirus infections has become acute.
Foamy Viruses
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Author : Axel Rethwilm
language : en
Publisher: Springer
Release Date : 2003-05-12
Foamy Viruses written by Axel Rethwilm and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-12 with Medical categories.
The aberrant replication pathway of foamy viruses distinguishes them from all other retroviruses. Many details have been accumulated over the past ten or so years. Most of the findings on foamy viruses were obtained by research on a single virus isolate previously called "human foamy virus", which appeared to be the first to be investigated on a molecular level. However, to the editor's knowledge, genuine human foamy viruses do not exist, but several trans-species transmissions of different simian foamy viruses from monkeys and apes to human hosts.
Arenaviruses I
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Author : M. B. A. Oldstone
language : en
Publisher:
Release Date : 2014-01-15
Arenaviruses I written by M. B. A. Oldstone and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
Laboratory Diagnosis Of Infectious Diseases Principles And Practice
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Author : Edwin H. Lennette
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Laboratory Diagnosis Of Infectious Diseases Principles And Practice written by Edwin H. Lennette and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
those who deal with infectious diseases on a daily This two volume work stems from the belief of the Editors that infectious diseases are not only very basis. much with us today but, more importantly, that they There are several excellent textbooks dealing will continue to playa significant global role in mor with medical microbiology, and there are equally bidity and mortality in all people. A continuing need well-recognized books devoted to infectious dis for an informed and knowledgeable community of eases. The Editors of this work, on the other hand, were persuaded that there was a need for a publica laboratory scientists is fundamental. Data describing tion that would bring together the most pertinent and the global impact of infectious diseases are difficult to come by. Fortunately, a recent thoughtful and relevant information on the principles and practice of provocative publication by Bennett et al. (1987) pro the laboratory diagnosis of infectious diseases and vides us with data derived from several consultants include clinical relationships. While this two volume that clearly delineate the impact of infectious dis text is directed toward the role of the laboratory in eases on the United States today.
The Arenaviridae
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Author : Maria S. Salvato
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Arenaviridae written by Maria S. Salvato and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In this volume, a distinguished international group of contributors present the latest molecular, organismal, and epidemiological research on arenaviruses. Their work will broaden both the clinician's and the researcher's knowledge of basic mechanisms of immunological tolerance, viral immunosuppression, the nature of protective immune responses to vaccination, and viral effects on cell functions.