Ariel Cd1
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Role Of Cd1 And Mr1 Restricted T Cells In Immunity And Disease
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Author : Kazuya Iwabuchi
language : en
Publisher: Frontiers Media SA
Release Date : 2019-10-18
Role Of Cd1 And Mr1 Restricted T Cells In Immunity And Disease written by Kazuya Iwabuchi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-18 with categories.
CD1 and MR1 are major histocompatibility complex (MHC) class I-related proteins that bind and present non-peptide antigens to subsets of T cells with specialized functions. CD1 proteins typically present lipid antigens to CD1-restricted T cells, whereas MR1 presents vitamin B-based ligands and a variety of drugs and drug-like molecules to MR1-restricted T cells. The CD1 family of antigen presenting molecules has been divided into two groups: Group 1 contains CD1a, CD1b and CD1c, and Group 2 contains CD1d. Additionally, CD1e is expressed intracellularly and is involved in the loading of lipid antigens onto Group 1 CD1 proteins. Humans express both Groups 1 and 2 CD1 proteins, whereas mice only express CD1d. Group 1 CD1 proteins present lipid antigens to T cells that generally express diverse T cell receptors (TCRs) and exhibit adaptive-like functions, whereas CD1d presents lipid antigens to subsets of T cells that express either diverse or highly restricted TCRs and exhibit innate-like functions. CD1d-restricted T cells are called natural killer T (NKT) cells, which includes Type I or invariant NKT (iNKT) cells expressing semi-invariant TCRs, and Type II NKT cells expressing more diverse TCRs. CD1-restricted T cells have been implicated in a wide variety of diseases, including cancer, infections, and autoimmune, inflammatory and metabolic diseases. Additionally, NKT cells have been targeted for immunotherapy of disease with ligands such as α-galactosylceramide for iNKT cells, or sulfatide for Type II NKT cells. Like iNKT cells, MR1-restricted T cells express semi-invariant TCRs and display innate-like functions. MR1-restricted T cells, also called mucosal-associated invariant T (MAIT) cells, have been implicated in immune responses against a variety of pathogens such as Mycobacterium tuberculosis, Pseudomonas aeruginosa, Helicobacter pylori, hepatitis C virus and influenza virus. Moreover, these cells contribute to autoimmune and inflammatory diseases, including colitis, rheumatoid arthritis, psoriasis, lupus, and diabetes.
Ariel
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Author : Ariel
language : en
Publisher:
Release Date : 1975
Ariel written by Ariel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with categories.
Is There A Text In This Cave Studies In The Textuality Of The Dead Sea Scrolls In Honour Of George J Brooke
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Author : Ariel Feldman
language : en
Publisher: BRILL
Release Date : 2017-06-01
Is There A Text In This Cave Studies In The Textuality Of The Dead Sea Scrolls In Honour Of George J Brooke written by Ariel Feldman and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-01 with Religion categories.
This volume explores the question of textuality in the Dead Sea Scrolls from a wide range of perspectives, including material aspects, performance, and the extent to which any of the texts relate (to) social realities in the Second Temple period.
Peronism As A Big Tent
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Author : Raanan Rein
language : en
Publisher: McGill-Queen's Press - MQUP
Release Date : 2022-02-15
Peronism As A Big Tent written by Raanan Rein and has been published by McGill-Queen's Press - MQUP this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-15 with Political Science categories.
Argentina’s populist movement, led by Juan Perón, welcomed people from a broad range of cultural backgrounds to join its ranks. Unlike most populist movements in Europe and North America, Peronism had an inclusive nature, rejecting racism and xenophobia. In Peronism as a Big Tent Raanan Rein and Ariel Noyjovich examine Peronism’s attempts at garnering the support of Argentines of Middle Eastern origins – be they Jewish, Maronite, Orthodox Catholic, Druze, or Muslim – in both Buenos Aires and the interior provinces. By following the process that started with Perón’s administration in the mid-1940s and culminated with the 1989 election of President Carlos Menem, of Syrian parentage, Rein and Noyjovich paint a nuanced picture of Argentina’s journey from failed attempts to build a mosque in Buenos Aires in 1950 to the inauguration of the King Fahd Islamic Cultural Center in the nation’s capital in the year 2000. Peronism as a Big Tent reflects on Perón’s own evolution from perceiving Argentina as a Catholic country with little room for those outside the faith to embracing a vision of a society that was multicultural and that welcomed and celebrated religious plurality. The legacy of this spirit of inclusiveness can still be felt today.
The Little Mermaid
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Author : Disney Book Group
language : en
Publisher: Disney Electronic Content
Release Date : 2016-01-05
The Little Mermaid written by Disney Book Group and has been published by Disney Electronic Content this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-05 with Juvenile Fiction categories.
Ariel is fascinated with life on land. On one of her visits above the surface, she meets a human prince and falls in love. Determined to be with her true love, she makes a risky deal with an evil sea witch and trades her voice for legs. Ariel embarks on the adventure of a lifetime, but soon finds that the fate of her father's kingdom is in her hands. This storybook includes beautiful, full-color art in the style of the beloved film, The Little Mermaid.
Managing Water Resources In A Time Of Global Change
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Author : Alberto Garrido
language : en
Publisher: Routledge
Release Date : 2009-01-13
Managing Water Resources In A Time Of Global Change written by Alberto Garrido and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-13 with Business & Economics categories.
Global change possesses serious challenges for water managers and scientists. In mountain areas, where water supplies for half of the world population originate, climate and hydrologic models are still subject to considerable uncertainty. And yet, critical decisions have to be taken to ensure adequate and safe water supplies to billions of people, millions of farmers and industries, without further deteriorating rivers and water bodies. While global warming is known to cause glaciers’ retreat and reduced snow packs around the world, it is not clear that mountain discharge will be lower. What is widely recognised is that water management must be adapted to accommodate significant regime changes. However, this inevitably involves managing transboundary rivers, adding further complexity to putting principles in practice. This book takes global warming and the importance of mountain areas in world water resources as the starting point. First, it provides detailed reviews of the processes going on in several rivers systems and world regions in Europe (Rhône and Ebro), North America (Canadian Rockies, Western US and Mexico), the Middle East (Jordan), Africa (Tunisia, Kenya and South Africa). These contexts provide case studies and examples that show the difficulties and potential for adaptation to global change. Land-use, economics, numerous modeling approaches are some of the cross-cutting issues covered in the chapters. The volume also includes the views of water practitioners, with two chapters authored by members of the US-Canada International Joint Commission, an industrialist from Western Canada and an environmental leader in Spain. By combining a rich set of contexts and approaches, the volume succeeds in offering a view of the global challenges faced by water agencies, international donors and researchers around the world. A case is made in some chapters to seek adaptive strategies rather than trying to reduce or control resources variability. This requires factoring in land-use, social and economic aspects, especially in developing countries. Another conclusion is that complex problems can and must be posed and negotiated with the help of models, mapping techniques and science-based facts. However complex these may be, there are ways to translate them to easily interpretable and visualisations of alternative scenarios and courses of action. This book provides numerous examples of the potential of such approaches to draft environmental programmes solve transboundary disputes and reduce the economic consequences of droughts and climate instability.
Cooperative Game Theory And Its Application To Natural Environmental And Water Resource Issues 2 Application To Natural And Environmental Resources
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Author : Stefano Zara, Fioravante Patrone, Ariel Dinar
language : en
Publisher: World Bank Publications
Release Date : 2006
Cooperative Game Theory And Its Application To Natural Environmental And Water Resource Issues 2 Application To Natural And Environmental Resources written by Stefano Zara, Fioravante Patrone, Ariel Dinar and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Acid rain categories.
Abstract: This paper provides a review of various applications of cooperative game theory (CGT) to issues of natural and environmental resources. With an increase in the level of competition over environmental and natural resources, the incidents of disputes have been at the center of allocation agreements. The paper reviews the cases of common pool resources such as fisheries and forests, and cases of environmental pollution such as acid rain, flow, and stock pollution. In addition to providing examples of cooperative solutions to allocation problems, the conclusion from this review suggests that cooperation over scarce environmental and natural resources is possible under a variety of physical conditions and institutional arrangements. CGT applications to international fishery disputes are especially useful in that they have been making headway in policy-related agreements among states and regions of the world. Forest applications are more local in nature, but of great relevance in solving disputes among communities and various levels of governments.
Disney The Little Mermaid
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Author :
language : en
Publisher: RH/Disney
Release Date : 2008
Disney The Little Mermaid written by and has been published by RH/Disney this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Juvenile Fiction categories.
Tells the story of how, when Ariel was a very young mermaid, King Triton banned all music beneath the sea.
Ariel The Spy
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Author : M.J. Carr
language : en
Publisher: Disney Press
Release Date : 1993-04-01
Ariel The Spy written by M.J. Carr and has been published by Disney Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-04-01 with Juvenile Fiction categories.
Ariel and her six older sisters live in a glorious castle deep below the ocean. Growing up in a palace isn't easy, especially with seven teenaged mermaids and a strict father living under one roof!
I Am Ariel Disney Princess
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Author : Andrea Posner-Sanchez
language : en
Publisher: Golden/Disney
Release Date : 2018-07-03
I Am Ariel Disney Princess written by Andrea Posner-Sanchez and has been published by Golden/Disney this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-03 with Juvenile Fiction categories.
A new Little Golden Book all about Ariel from Disney's The Little Mermaid! What are the Little Mermaid's favorite things to do? Who are Ariel's best friends? Find out the answers to these questions and much more in this new Little Golden Book all about Disney Princess Ariel, the star of the beloved Disney movie The Little Mermaid. This Little Golden Book is beautifully illustrated with a unique art style and features Flounder, Sebastian, Scuttle, Prince Eric, and others from the hit animated film. It is a must-have for children ages 2 to 5, plus all The Little Mermaid fans--and collectors--of any age! This Little Golden Book is part of the charming "I Am..." series, which provides a unique look at favorite Disney characters.