Aspects Of Reversible Drug Human Serum Albumin Binding

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Aspects Of Reversible Drug Human Serum Albumin Binding

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Author : Jesper Østergaard
language : en
Publisher:
Release Date : 2003

Aspects Of Reversible Drug Human Serum Albumin Binding written by Jesper Østergaard and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.

Reversible Ligand Binding To Human Serum Albumin

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Author : Henrik Vorum
language : en
Publisher:
Release Date : 1999

Reversible Ligand Binding To Human Serum Albumin written by Henrik Vorum and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.

Albumin Structure Function And Uses

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Author : Victor M. Rosenoer
language : en
Publisher: Elsevier
Release Date : 2014-05-18

Albumin Structure Function And Uses written by Victor M. Rosenoer and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-18 with Medical categories.

Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.

Principles And Practice Of Chromatography

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Author : B. Ravindranath
language : en
Publisher: Ellis Horwood
Release Date : 1989

Principles And Practice Of Chromatography written by B. Ravindranath and has been published by Ellis Horwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Science categories.

All About Albumin

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Author : Theodore Peters Jr.
language : en
Publisher: Academic Press
Release Date : 1995-12-21

All About Albumin written by Theodore Peters Jr. and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-12-21 with Science categories.

The first of its kind, All About Albumin summarizes the chemistry, genetics, metabolism, clinical implications, and commercial aspects of albumin. It provides the most up-to-date sequences, structures, and compositions of many species, and includes more than 2000 references. Includes up-to-date sequences, structures, and compositions of many species Reviews the protein chemistry, genetic control, and metabolism of albumin Covers medical and cell culture applications in vivo and in vitro, with a section on handling albumin in the laboratory Presents the relationship of albumin to its superfamily with an updated scheme for their evolution First complete coverage of all aspects of serum albumin in one volume, with more than 2000 references

Introduction To Basics Of Pharmacology And Toxicology

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Author : Gerard Marshall Raj
language : en
Publisher: Springer Nature
Release Date : 2019-11-16

Introduction To Basics Of Pharmacology And Toxicology written by Gerard Marshall Raj and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-16 with Medical categories.

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.

Drug Like Properties Concepts Structure Design And Methods

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Author : Li Di
language : en
Publisher: Elsevier
Release Date : 2010-07-26

Drug Like Properties Concepts Structure Design And Methods written by Li Di and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-26 with Science categories.

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. Serves as an essential working handbook aimed at scientists and students in medicinal chemistry Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Mechanisms Of Drug Toxicity

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Author : H. Rašková
language : en
Publisher: Elsevier
Release Date : 2013-10-22

Mechanisms Of Drug Toxicity written by H. Rašková and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.

Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.

Lipoproteins Apolipoproteins And Lipases

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Author :
language : en
Publisher: Academic Press
Release Date : 1994-03-10

Lipoproteins Apolipoproteins And Lipases written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-03-10 with Science categories.

This volume contains eight chapters that present both new and reviewed information fundamental to a clear understanding of lipid catabolism and transport at the molecular level. Three-dimensional structures of important serum lipoproteins, apolipoproteins, and lipases, utilizing X-ray data when available, are emphasized, and an attempt is made to relate structures to function. Amphipathic helix Apolipoprotein E Lipophorin Structure of serum albumin Lipid binding proteins Apolipoprotein B Low-density lipoprotein

Physico Chemical Aspects Of Dosage Forms And Biopharmaceutics

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Author : Amit Kumar Nayak
language : en
Publisher: Elsevier
Release Date : 2024-08-30

Physico Chemical Aspects Of Dosage Forms And Biopharmaceutics written by Amit Kumar Nayak and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-30 with Medical categories.

Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics. In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence. Provides extensive details on the most recent developments in biopharmaceutics Contains contributions from leading experts from academia, research, industry and regulatory agencies Includes high quality illustrations, flow charts and tables for easier understanding of the concepts Discusses practical examples and research case studies