Atra As S
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The Ecology And Behavior Of Amphibians
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Author : Kentwood D. Wells
language : en
Publisher: University of Chicago Press
Release Date : 2010-02-15
The Ecology And Behavior Of Amphibians written by Kentwood D. Wells and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-15 with Science categories.
Consisting of more than six thousand species, amphibians are more diverse than mammals and are found on every continent save Antarctica. Despite the abundance and diversity of these animals, many aspects of the biology of amphibians remain unstudied or misunderstood. The Ecology and Behavior of Amphibians aims to fill this gap in the literature on this remarkable taxon. It is a celebration of the diversity of amphibian life and the ecological and behavioral adaptations that have made it a successful component of terrestrial and aquatic ecosystems. Synthesizing seventy years of research on amphibian biology, Kentwood D. Wells addresses all major areas of inquiry, including phylogeny, classification, and morphology; aspects of physiological ecology such as water and temperature relations, respiration, metabolism, and energetics; movements and orientation; communication and social behavior; reproduction and parental care; ecology and behavior of amphibian larvae and ecological aspects of metamorphosis; ecological impact of predation on amphibian populations and antipredator defenses; and aspects of amphibian community ecology. With an eye towards modern concerns, The Ecology and Behavior of Amphibians concludes with a chapter devoted to amphibian conservation. An unprecedented scholarly contribution to amphibian biology, this book is eagerly anticipated among specialists.
The New And Complete Dictionary Of The English Language Grammatical Dissertations A M
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Author : John Ash
language : en
Publisher:
Release Date : 1775
The New And Complete Dictionary Of The English Language Grammatical Dissertations A M written by John Ash and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1775 with English language categories.
The New And Complete Dictionary Of The English Language
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Author : John Ash
language : en
Publisher:
Release Date : 1795
The New And Complete Dictionary Of The English Language written by John Ash and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1795 with categories.
The Role Of P27 Phosphorylation In Mediating Atra Sensitivity Of Ovarian Carcinoma Cells
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Author : Maria Radu
language : en
Publisher:
Release Date : 2008
The Role Of P27 Phosphorylation In Mediating Atra Sensitivity Of Ovarian Carcinoma Cells written by Maria Radu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
All trans retinoic acid (atRA) has been shown to inhibit the growth of CAOV3 ovarian carcinoma cells. This results from arrest of the cell cycle during the G1 phase. G1 checkpoint is regulated by a multitude of molecules, including the retinoblastoma family of proteins, cyclin dependent kinases (Cdks), and cyclin dependent kinase inhibitors. P27, a cyclin dependent kinase inhibitor regulating G1 checkpoint has been shown to have elevated levels in response to atRA treatment. In these studies we investigated the role of p27 phosphorylation in mediating atRA induced growth inhibition. Our results show that atRA treatment of atRA sensitive CAOV3 cells leads to an increase in the levels of S10 phosphorylation of p27 in both nuclear and cytoplasmic cell compartments. This increase was accompanied by a decrease in the levels of skp2 protein, protein that plays a critical role in the degradation of p27. Similar results were not observed in SKOV3 cells which are not growth inhibited by atRA treatment. Finally, we demonstrated that overexpression of a mutant of p27 that cannot be phosphorylated on S10 induces a dominant negative effect on the endogenous p27 activity. This dominant negative effect reverses the atRA effect on p27 binding to CDKs, on inhibition of CDK activity, on the expression of S phase genes and ultimately on the inhibition of growth of ovarian carcinoma cells. These results suggest that hypophosphorylation of the serine10 locus of p27 might be one of the mechanisms that lead to atRA resistance of ovarian carcinoma cell. It is possible that atRA resistant ovarian tumors constitute an environment that hinders S10 phosphorylation and that by modulating the activity of the kinase(s) responsible for this event the atRA resistance can be overcome.
Fungal Toxins
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Author : Solomon Kadis
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Fungal Toxins written by Solomon Kadis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Microbial Toxins: A Comprehensive Treatise, Volume VIII, Fungal Toxins is devoted to topics related to algal and fungal toxins and includes critically reviewed articles from different experts in related fields. The text is divided into three sections. Section A covers coumarins — its isolation, identification, biological action, natural occurrence, and uses. Section B deals with the epizootiology, clinical characteristics, and pathological findings of Stachybotryotoxicosis. Section C talks about phytopathogenic and helminthosporium toxins, toxic peptides found in Amanita species as well as other mushroom toxins, compounds accumulating in plants after an infection, and ergot. The book is recommended for microbiologists and toxicologists, especially those who would like to know more about the toxins produced by algae and fungi and their effects.
The Oratorical Dictionary
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Author : John Newland Maffitt
language : en
Publisher:
Release Date : 1835
The Oratorical Dictionary written by John Newland Maffitt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1835 with English language categories.
Diagnostic And Therapeutic Advances In Hematologic Malignancies
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Author : Martin S. Tallman
language : en
Publisher: Springer Science & Business Media
Release Date : 1998-12-31
Diagnostic And Therapeutic Advances In Hematologic Malignancies written by Martin S. Tallman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-12-31 with Medical categories.
There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies will provide practitioners and academic clinicians with a better understanding of the constantly evolving concepts in this area.
Agriculture Monograph
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Author : United States. Department of Agriculture
language : en
Publisher:
Release Date : 1951
Agriculture Monograph written by United States. Department of Agriculture and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1951 with Agriculture categories.
Mycotoxin Protocols
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Author : Mary W. Trucksess
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05
Mycotoxin Protocols written by Mary W. Trucksess and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Medical categories.
Mycotoxins produced by molds are common contaminants of many important crops, including wheat, corn, rice, and peanuts. Some mycotoxins are found in fruits and vegetables. These contaminants have a broad range of toxic effects, including carcinogenicity, neurotoxicity, and reproductive and developmental toxicity. The occurrence of mycotoxins in foods is an unavoidable worldwide problem. About 80 countries have imposed regulatory limits to minimize human and animal exposure to mycotoxins. Regulatory limits, including international standards, have tremendous economic impact and must be developed using science-based risk assessments. The purpose of Mycotoxin Protocols is to provide the scientific and technological basis for analytical methods for use in obtaining the exposure data needed for risk assessments. Mycotoxin Protocols is divided into four sections, which are interc- nected. The first section: Chapters 1–5 describe the general techniques for mycotoxin analysis with emphasis on the importance of method validation based on statistical parameters; sampling procedures for collecting a sample as representative as possible of a bulk lot; the isolation of mycotoxins for use as analytical standards or for toxicological studies; the evaluation of purity and preparation of standards; and the detection and identification of impu- ties in isolated mycotoxins. Sections 2–4: Chapters 6–19 describe the most current chromatographic and immunochemical methods for studies on the major mycotoxins.
Salamanders Of The Old World
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Author : Max Sparreboom
language : en
Publisher: BRILL
Release Date : 2014-09-08
Salamanders Of The Old World written by Max Sparreboom and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-08 with Science categories.
Salamanders of the Old World is a new in-depth reference work covering all the salamander species of Europe, Asia, and North Africa. A marvellous addition for the herp community that comes recommended for researchers, managers, conservationists, students, and salamander enthusiasts. Salamanders of the Old World • features information on biology and life history of salamanders • includes over 150 species of Europe, Asia, and North Africa • richly illustrated • focuses on habitat, behaviour, and reproduction • information on identification, eggs and larvae, and threats and species conservation • distribution maps for all species • an extensive reference list. Published in cooperation between KNNV Publishing and Naturalis Biodiversity Centre (The Netherlands).