B Lymphocytes In Human Disease

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B Lymphocytes In Human Disease

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Author : Angus Graham Bird
language : en
Publisher:
Release Date : 1988

B Lymphocytes In Human Disease written by Angus Graham Bird and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.

During the past two decades, cells of the B-lymphocyte lineage have been the subject of intensive research. B-lymphocytes and antibodies play a crucial role in the body's defense against infection, but can also be responsible for producing certain diseases. This volume provides an up-to-date discussion of the cellular and molecular biology of antibodies and the cells that produce them. Researchers discuss the fundamentals of B-cell biology that are crucial to understanding how cells and their antibody products generate a range of malignant, autoimmune and immunodeficiency disorders. The discussion of human diseases in the second part of the book provides an interface between recent advances in B-cell biology and B-cell related disease processes.

B Cells In Immunity And Tolerance

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Author : Ji-Yang Wang
language : en
Publisher: Springer Nature
Release Date : 2020-04-22

B Cells In Immunity And Tolerance written by Ji-Yang Wang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-22 with Medical categories.

This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.

Human B Lymphocyte Function

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Author : Anthony S. Fauci
language : en
Publisher: Raven Press (ID)
Release Date : 1982

Human B Lymphocyte Function written by Anthony S. Fauci and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with B cells categories.

B Cell Trophic Factors And B Cell Antagonism In Autoimmune Disease

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Author : William Stohl
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2005-01-01

B Cell Trophic Factors And B Cell Antagonism In Autoimmune Disease written by William Stohl and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-01 with Medical categories.

The understanding of B cell biology has increased and expanded enormously in the last three decades. It is now known that B cells, in addition to just differentiating into antibody-secreting cells, serve many other vital functions. For example, their roles as antigen-presenting cells and cytokine-producing cells as well as effector cells and regulatory cells are well appreciated now. Indeed, the pathologic role of B cells in many autoimmune disorders may be largely autoantibody-independent. Today, the B cell is of considerable interest not only to immunologists but also to mainstream clinicians and scientists. The current volume covers the latest information on the functions of B cells in normal and disease states, and their therapeutic antagonism. Chapters cover cutting-edge topics from the basic to the clinical, including B cells in infection and autoimmunity, CD19-CD21 signal transduction complex, marginal zone B cell physiology and disease, B cell growth and differentiation, their role in rheumatoid arthritis, SLE treatment, the BAFF/APRIL system and B lymphocyte malignancies. This book is recommended reading for cellular and molecular immunologists as well as for rheumatologists, hematologists and clinical immunologists, and all those interested in human diseases in which B cells play an important contributory role.

Molecular Biology Of B Cells

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Author : Tasuku Honjo
language : en
Publisher: Elsevier
Release Date : 2014-10-09

Molecular Biology Of B Cells written by Tasuku Honjo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-09 with Medical categories.

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response

Human B Cell Populations

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Author : M. Ferrarini
language : en
Publisher: S Karger Ag
Release Date : 1997

Human B Cell Populations written by M. Ferrarini and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.

B cells used to be considered as a homogeneous population of cells destined to produce antibodies of increasing affinity and to maintain an immunological memory. In recent years, it has been determined that B cells can be subdivided into different subsets characterized by distinct morphologic, phenotypic, and functional features. Presenting results of research work on the definition of B cell subset populations, this book explains the basic mechanisms that control B cell activation, stimulation and regulation. Articles include studies on both normal and malignant B cells and describe the mechanisms underlying T-B cell interactions during the immune response. The most important advances in the field of immunodeficiency are also reported. This volume will be essential not only for basic and clinical immunologists, but also for hematologists, pathologists and rheumatologists with a special interest in the pathogenesis of lymphoproliferative or autoimmune disorders.

B Cell Biology In Autoimmunity

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Author : David Ahmad Nemazee
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2003

B Cell Biology In Autoimmunity written by David Ahmad Nemazee and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.

B cells play a central role not only in adaptive immunity, but also in autoimmunity. To understand how B cells are normally prevented from reacting to self-tissue, what goes wrong in autoimmunity, and how B cells contribute to it is the aim of this book. This volume includes more than a dozen in-depth reviews by researchers specializing in various aspects of basic B cell biology that have relevance to autoimmune diseases. These up-to-date chapters present the latest information on B cell signal transduction, apoptosis, genetics and molecular biology. Also featured are chapters with special reference to particular autoimmune diseases in which B cells have been shown to play a critical role, such as type 1 diabetes, chronic graft-versus-host disease and lupus erythematosus. Further topics covered include the role of the complement system, rheumatoid factors, and anti-DNA autoantibodies as well as important related areas such as natural autoantibodies, B cell immune tolerance, Toll receptor signaling, and the immunobiology of BAFF/BLyS. Both basic researchers and clinician scientists who wish to understand the role of B lymphocytes in immune tolerance and autoimmunity will benefit from this timely publication.

Human B Lymphocyte Function

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Author : Anthony S. Fauci
language : en
Publisher:
Release Date : 1982

Human B Lymphocyte Function written by Anthony S. Fauci and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with B cells categories.

Janeway S Immunobiology

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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22

Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Proceedings Of The Usphs Workshop On Laboratory And Epidemiologic Approaches To Determining The Role Of Environmental Exposure As Risk Factors For B Cell Chronic Lymphocytic Leukemia And Other B Cell Lymphoproliferative Disorders

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Author : Gerald E. Marti
language : en
Publisher:
Release Date : 1997

Proceedings Of The Usphs Workshop On Laboratory And Epidemiologic Approaches To Determining The Role Of Environmental Exposure As Risk Factors For B Cell Chronic Lymphocytic Leukemia And Other B Cell Lymphoproliferative Disorders written by Gerald E. Marti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Chronic lymphocytic leukemia categories.