Bacterial Capsules
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Bacterial Capsules
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Author : Klaus Jann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Bacterial Capsules written by Klaus Jann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Many bacteria, such as certain Neisseria and Haemophilus or Escherichia coli, are able to withstand the bactericidal activity of complement and phagocytes. This bacterial self protection is brought about by encapsulation. Bacterial capsules thus enable the pathogenic bacteria to survive in the host by counter action or evasion of the nonspecific host defense in the early pre immune phase of an infection. It is only in the late immune phase of the infection, when specific anticapsular antibodies are formed and enforce the host's defense system, that this protective action is overcome. Encapsulated bacteria are then killed and eliminated. Interestingly, some capsules can not or only inefficiently be handled by the immune system. The ensuing lack of antibody formation results in a prolonged susceptibility of the host to the pathogenic bacteria exhibiting such capsules. It was found that bacterial capsules consist of acidic poly saccharides. From this it followed that the role of the capsules in the interaction of encapsulated bacteria with the host may be due to the chemistry of the capsular polysaccharides. This led to intensive studies of capsular polysaccharides in many laboratories. Our increasing knowledge of the structural features of capsular polysaccharides prompted not only immuno chemical studies analyzing the interactions of these poly saccharide antigens and characterizing the epitopes, but also investigations into their biosynthesis. These studies were complemented and supported by genetic analyses. Today many interdisciplinary investigations of capsular polysaccharides are in progress.
A Note On The Demonstration Of Bacterial Capsules By The Phase Contrast Method
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Author : Hans Evald Ottosen
language : da
Publisher:
Release Date : 1957
A Note On The Demonstration Of Bacterial Capsules By The Phase Contrast Method written by Hans Evald Ottosen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1957 with categories.
A Note On The Demonstration Of Bacterial Capsules By The Phase Contrast Method
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Author : H. E. Ottosen
language : en
Publisher:
Release Date : 1957
A Note On The Demonstration Of Bacterial Capsules By The Phase Contrast Method written by H. E. Ottosen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1957 with categories.
A New Stain For Bacterial Capsules With Special Reference To Pneumococci
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Author : Edward Carl Rosenow
language : en
Publisher:
Release Date : 1911*
A New Stain For Bacterial Capsules With Special Reference To Pneumococci written by Edward Carl Rosenow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1911* with categories.
Staining Of Bacterial Capsules In Films And Sections
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Author : Richard Muir (demonstrator of pathological and bacteriological methods.)
language : en
Publisher:
Release Date : 1916*
Staining Of Bacterial Capsules In Films And Sections written by Richard Muir (demonstrator of pathological and bacteriological methods.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1916* with categories.
Assembly Of Conserved Glycolipid Termini In Gram Negative Bacterial Capsules Synthesized By Abc Transporter Dependent Pathways
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Author : Liam Doyle
language : en
Publisher:
Release Date : 2016
Assembly Of Conserved Glycolipid Termini In Gram Negative Bacterial Capsules Synthesized By Abc Transporter Dependent Pathways written by Liam Doyle and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
The Application Of Immunofluorescence To Genetic Studies Of Bacterial Capsules
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Author : Vittorio R. Tartagni
language : en
Publisher:
Release Date : 1968
The Application Of Immunofluorescence To Genetic Studies Of Bacterial Capsules written by Vittorio R. Tartagni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with categories.
Concepts In Bacterial Virulence
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Author : Wayne Russell
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2005-01-01
Concepts In Bacterial Virulence written by Wayne Russell and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-01 with Medical categories.
Over the past few decades the increase in bacterial resistance has led to the search for novel antibacterial therapies and a better understanding of virulence mechanisms used by pathogens. It has been shown that the interplay between pathogenic bacteria and the host is complex and finely balanced. Successful pathogens can manipulate host homeostasis and normal cell functions using a variety of molecular strategies. This volume of the Karger book series Contributions to Microbiology summarizes some of the most important bacterial virulence mechanisms. Eminent scientists provide an update on recent findings in their fields. This state-of-the-art account will not only attract the interest of clinical and preclinical researchers, but will also be of great value to students with an interest in medicine, biology, chemistry, and infectious diseases.
Capsular Polysaccharide Structure Governs Virulence In Acinetobacter Baumannii Lac 4
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Author : Mohammed Tariq Qayum
language : en
Publisher:
Release Date : 2022
Capsular Polysaccharide Structure Governs Virulence In Acinetobacter Baumannii Lac 4 written by Mohammed Tariq Qayum and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Acinetobacter baumannii is an emerging gram-negative pathogen that is listed by the center of disease control as an urgent threat and is part of a select group of pathogens known as the ESKAPE pathogens due to its ability to continuously escape the lethal action of antibiotics. A. baumannii infection is most common in the healthcare setting putting immunocompromised patients at increased risk of infection through disease such as ventilator associated pneumonia. For pathogens such as A. baumannii, the mechanisms of antimicrobial resistance are well understood but the understanding of the determinants of virulence have yet to catch up. A virulence factor of particular interest in the scientific community is the capsular polysaccharide and how it can play a role in pathogenicity. Bacterial capsules, comprised of tightly packed polysaccharide units, have been shown to provide various strains of bacteria protection from environmental pressures such as host immune response and antimicrobial agents. However, capsule loci in A. baumannii are highly variable providing the question if capsular virulence is specific to certain capsule types or universal. This study generated an unmarked knockout mutant of LAC-4 in which the capsule locus has been deleted. The resulting mutant was evaluated with in vitro cell based assays and against an established mouse model of bacterial systemic infection. Capsule deficient mutants of LAC-4 were found to be significantly less virulent than the wildtype LAC-4 strain showing that the capsule gene cluster appears to contribute to LAC-4's hypervirulence.
Structural And Functional Relationships In Prokaryotes
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Author : Larry Barton
language : en
Publisher: Springer Science & Business Media
Release Date : 2005
Structural And Functional Relationships In Prokaryotes written by Larry Barton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
This new textbook on bacterial physiology is aimed at senior level students pursuing a one-semester course in the biology or microbiology curriculum. The text takes a balanced view of prokaryotic physiology, discussing both bioenergetics and bacterial metabolism in a way that establishes general principles and concepts and emphasizes throughout the information gained from model systems. The book also covers some experimental design issues, giving students an appreciation of the practical aspects and consequences of bacterial metabolism. It also stimulates students’ interests in future developments in the field by including discussions by five world-famous bacterial physiologists about future developments in the field.