Behavioral Models In Stress Research
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Behavioral Models In Stress Research
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Author : Allan V. Kalueff
language : en
Publisher: Nova Publishers
Release Date : 2008
Behavioral Models In Stress Research written by Allan V. Kalueff and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
Stress is an adaptive response that has developed throughout evolution, and is associated with multiple changes in the biochemistry, histology and physiology of an organism. As stress may induce or contribute to multiple neuropsychiatric disorders, the rigorous investigation of the neural substrates of stress has become a critical endeavour of contemporary biomedical science. This book explores the physiological responses that researchers have attempted to assess in stress-evoked behavioural changes, using both human and animal "experimental" models in clinical and non-clinical research. Though all aspects of the field have their challenges, animal experimental research of stress is a particularly difficult but meaningful task. This book provides succinct and relevant summaries of progress in the area of assessing stress response and the conditions contributing to it.
Stress And Mental Disorders
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Author : Richard McCarty
language : en
Publisher: Oxford University Press, USA
Release Date : 2020
Stress And Mental Disorders written by Richard McCarty and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Medical categories.
Stress has been recognized as an important factor in the development or recurrence of various mental disorders, from major depressive disorder to bipolar disorder to anxiety disorders. Stressful stimuli also appear to exert their effects by acting upon individuals with susceptible genotypes. Over the past 50 years, animal models have been developed to study these dynamic interactions between stressful stimuli and genetically susceptible individuals during prenatal and postnatal development and into adulthood. Stress and Mental Disorders: Insights from Animal Models begins with a discussion of the history of psychiatric diagnosis and the recent goal of moving toward precision psychiatry, followed by a review of clinical research on connections between stressful stimuli and the development of psychiatric disorders. Chapters are also included on neuroendocrine, immune, and brain systems involved in responses to stress. Additional chapters focus on the development of animal models in psychiatry and the susceptibility of the developing organism to stressful stimuli. Subsequent chapters are devoted to animal models of specific stress-sensitive psychiatric disorders, including schizophrenia, autism spectrum disorders, bipolar disorder, anxiety disorders, depression, and post-traumatic stress disorder. These chapters also focus on identification of promising molecular targets for development of new drug therapies. The section concludes with a chapter on animal models of resilience to stress-induced behavioral alterations as a newer approach to understanding why some animals are susceptible to stress and others are resilient, even though they are essentially genetically identical. The final chapter discusses how these basic laboratory studies are providing promising leads for future breakthroughs in the diagnosis, treatment, and prevention of mental disorders.
The Neurobiological Basis Of Suicide
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Author : Yogesh Dwivedi
language : en
Publisher: CRC Press
Release Date : 2012-06-25
The Neurobiological Basis Of Suicide written by Yogesh Dwivedi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-25 with Medical categories.
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Experimental Animal Models In Neurobehavioral Research
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Author : Allan V. Kalueff
language : en
Publisher:
Release Date : 2009
Experimental Animal Models In Neurobehavioral Research written by Allan V. Kalueff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
Behavioural research has been an exciting staple of the neuroscientific community's efforts in combating the rising challenges of mental healthcare. New innovations are bringing a greater understanding of the pathogenic mechanisms behind the disorders and allowing for progress towards their remedies. this translational approach, using newly developed animal modes, is of critical importance for the study of neuropsychiatric disorders. While the differences between the subjects of clinical research and basic research are obvious, there are many neurobiological similarities that allow for the possibility of creating an accurate animal analogue of a human disorder. These tools contribute to translational research and are the best hope for countering the challenges facing the field of mental health. This book provides chapters on a range of issues in biopsychology and behavioural neuroscience. It offers innovative methodological and conceptual advances regarding topics such as sleep, depression, and anxiety, as well as how these domains interact. All authors of the book are recognised experts in the field, and have written their chapters for an international audience of basic and clinical neuroscientists who are interested in behavioural neurophenotyping. The writing will also be accessible to students at the undergraduate level, while still providing an important update to graduate students and professional researchers in the disciplines of psychology, biology, and neuroscience on this rapidly developing field.
Behavioral Genetics Of The Mouse Volume 1 Genetics Of Behavioral Phenotypes
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Author : Wim E. Crusio
language : en
Publisher: Cambridge University Press
Release Date : 2013-04-25
Behavioral Genetics Of The Mouse Volume 1 Genetics Of Behavioral Phenotypes written by Wim E. Crusio and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-25 with Science categories.
The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Methods Of Behavior Analysis In Neuroscience
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Author : Jerry J. Buccafusco
language : en
Publisher: CRC Press
Release Date : 2000-08-29
Methods Of Behavior Analysis In Neuroscience written by Jerry J. Buccafusco and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-08-29 with Medical categories.
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Type A Behavior Pattern
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Author : Virginia Ann Price
language : en
Publisher:
Release Date : 1982
Type A Behavior Pattern written by Virginia Ann Price and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Education categories.
Treating Depression Anxiety And Stress In Ethnic And Racial Groups
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Author : Edward C. Chang
language : en
Publisher: Cultural, Racial, and Ethnic P
Release Date : 2018
Treating Depression Anxiety And Stress In Ethnic And Racial Groups written by Edward C. Chang and has been published by Cultural, Racial, and Ethnic P this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Psychology categories.
This volume shows therapists how to adapt cognitive behavioral treatments for use with racial and ethnic minority clients.
Depression In Parents Parenting And Children
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2009-10-28
Depression In Parents Parenting And Children written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-28 with Medical categories.
Depression is a widespread condition affecting approximately 7.5 million parents in the U.S. each year and may be putting at least 15 million children at risk for adverse health outcomes. Based on evidentiary studies, major depression in either parent can interfere with parenting quality and increase the risk of children developing mental, behavioral and social problems. Depression in Parents, Parenting, and Children highlights disparities in the prevalence, identification, treatment, and prevention of parental depression among different sociodemographic populations. It also outlines strategies for effective intervention and identifies the need for a more interdisciplinary approach that takes biological, psychological, behavioral, interpersonal, and social contexts into consideration. A major challenge to the effective management of parental depression is developing a treatment and prevention strategy that can be introduced within a two-generation framework, conducive for parents and their children. Thus far, both the federal and state response to the problem has been fragmented, poorly funded, and lacking proper oversight. This study examines options for widespread implementation of best practices as well as strategies that can be effective in diverse service settings for diverse populations of children and their families. The delivery of adequate screening and successful detection and treatment of a depressive illness and prevention of its effects on parenting and the health of children is a formidable challenge to modern health care systems. This study offers seven solid recommendations designed to increase awareness about and remove barriers to care for both the depressed adult and prevention of effects in the child. The report will be of particular interest to federal health officers, mental and behavioral health providers in diverse parts of health care delivery systems, health policy staff, state legislators, and the general public.
Recognition And Alleviation Of Distress In Laboratory Animals
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2008-04-10
Recognition And Alleviation Of Distress In Laboratory Animals written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-10 with Science categories.
Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. This new book from the Institute for Laboratory Animal Research (ILAR) at the National Research Council, Recognition and Alleviation of Distress in Laboratory Animals, focuses on the stress and distress which is experienced by animals when used in laboratory research. This book aims to educate laboratory animal veterinarians; students, researchers, and investigators; animal care staff, as well as animal welfare officers on the current scientific and ethical issues associated with stress and distress in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines. Recognition and Alleviation of Distress in Laboratory Animals focuses specifically on the scientific understanding of the causes and the functions of stress and distress, the transformation of stress to distress, and the identification of principles for the recognition and alleviation of distress. This book discusses the role of humane endpoints in situations of distress and principles for the minimization of distress in laboratory animals. It also identifies areas in which further scientific investigation is needed to improve laboratory animal welfare in order to adhere to scientific and ethical principles that promote humane care and practice.