Bellocchio S Chin

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Bellocchio S Chin

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Author : Marco Bellocchio
language : en
Publisher: Penguin Group
Release Date : 1970-08-25

Bellocchio S Chin written by Marco Bellocchio and has been published by Penguin Group this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970-08-25 with categories.

Hemodiafiltration

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Author : Claudio Ronco
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2007-01-01

Hemodiafiltration written by Claudio Ronco and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-01 with Medical categories.

A concise handbook on clinical and technical possibilities The application of hemodiafiltration has been restricted until recently, when a broader clinical application has been made possible due to evidence from large studies and clinical investigations. This book provides an updated review of the evolution, advances and recent results achieved by hemodiafiltration in the clinical arena. The first part is devoted to historical notes and an outline of the evolution of different forms of hemodiafiltration, made possible by technological developments in the fields of membranes, machines and fluids. The next section describes the theoretical rationale for hemodiafiltration, providing a detailed analysis of the involved mass separation processes, the hydraulic properties of the dialyzers, fluid mechanics and crossfiltration in hollow fiber hemodialyzers. An outline of different hemodiafiltration techniques, also reporting peculiar transport mechanisms and related technology, is given next, and a section on the clinical effects of hemodiafiltration concludes this book. Including different technologies, the publication offers a complete overview of the technical and clinical possibilities provided by hemodiafiltration in its widest concept, ranging from the molecular basis to the most practical application. It will be a valuable tool for the implementation of hemodiafiltration in daily practice aimed at beginners and experts, scientists and physicians, students and senior faculty members alike.

Crossroads Between Innate And Adaptive Immunity Iv

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Author : Peter D. Katsikis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-01

Crossroads Between Innate And Adaptive Immunity Iv written by Peter D. Katsikis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-01 with Medical categories.

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions. ​

Neural Networks For Pattern Recognition

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Author : Christopher M. Bishop
language : en
Publisher: Oxford University Press
Release Date : 1995-11-23

Neural Networks For Pattern Recognition written by Christopher M. Bishop and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-11-23 with Computers categories.

Statistical pattern recognition; Probability density estimation; Single-layer networks; The multi-layer perceptron; Radial basis functions; Error functions; Parameter optimization algorithms; Pre-processing and feature extraction; Learning and generalization; Bayesian techniques; Appendix; References; Index.

High Density Lipoproteins

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Author : Arnold von Eckardstein
language : en
Publisher: Springer
Release Date : 2015-01-13

High Density Lipoproteins written by Arnold von Eckardstein and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-13 with Medical categories.

In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.

Propulsion And Power

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Author : Joachim Kurzke
language : en
Publisher: Springer
Release Date : 2018-05-28

Propulsion And Power written by Joachim Kurzke and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-28 with Technology & Engineering categories.

The book is written for engineers and students who wish to address the preliminary design of gas turbine engines, as well as the associated performance calculations, in a practical manner. A basic knowledge of thermodynamics and turbomachinery is a prerequisite for understanding the concepts and ideas described. The book is also intended for teachers as a source of information for lecture materials and exercises for their students. It is extensively illustrated with examples and data from real engine cycles, all of which can be reproduced with GasTurb (TM). It discusses the practical application of thermodynamic, aerodynamic and mechanical principles. The authors describe the theoretical background of the simulation elements and the relevant correlations through which they are applied, however they refrain from detailed scientific derivations.

Potential Neurotoxic Effects Of Perioperative Factors

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Author : Zhongcong Xie
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-21

Potential Neurotoxic Effects Of Perioperative Factors written by Zhongcong Xie and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-21 with Science categories.

Idiopathic Pulmonary Fibrosis

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Author : Joseph P. Lynch
language : en
Publisher: CRC Press
Release Date : 2003-12-18

Idiopathic Pulmonary Fibrosis written by Joseph P. Lynch and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-18 with Medical categories.

A discussion of the epidemiology, clinical features, and differential diagnoses of idiopathic pulmonary fibrosis (IPF). Key topics include the role of polymorphonuclear leukocytes in the pathogenesis of pulmonary fibrosis, and current treatment options, including medical therapy and lung transplantation.

Target Pattern Recognition In Innate Immunity

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Author : Uday Kishore
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-01

Target Pattern Recognition In Innate Immunity written by Uday Kishore and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-01 with Medical categories.

Target pattern recognition in innate immunity is responsible for the immediate, usually protective, responses shown against invading microorganisms, and it is the principal feature of self and non-self recognition by virtue of the recognition of structures on the microbial pathogens, which are not found on host cells. This is an area that has been very actively researched, over approximately the past 12 years, and therefore this volume provides a timely comprehensive, and up to date, summary of the types and range of cell surface, intracellular, and secreted, host proteins involved in the recognition of microbial products, and of the protective mechanisms triggered as a result of the recognition events. The Toll-like receptors, first described in Drosophila and now well-characterised on human cells, provide an excellent demonstration of the wide range of different microbial products recognised by this family of receptors and of the signalling pathways which are triggered thus leading to induction of inflammatory cytokines and the activation of genes producing antimicrobial products. In addition, several cell surface proteins involved in target pattern recognition have been described on the surfaces of macrophages (macrophage mannose receptor and macrophage scavenger receptors), and on dendritic cells (DEC205), and to be involved with the uptake and clearance of whole microorganisms and polyanioic ligands. Pattern recognition is also utilised by intracellular receptors, with NOD-like receptors in the cytosol recognizing microbial molecules and activating the production of inflammatory cytokines or pathways that induce the production of inflammatory molecules. Secreted proteins, such as the pentraxins, which includes the acute phase reacting, C-reactive protein (CRP) and serum amyloid protein (SAP), and the collectins (mannan binding lectin, lung surfactant protein A and D) and ficolins can also readily recruit killing and clearance systems. Indeed, the serum complement system, which is one of the major defence systems in the bloodstream, is efficiently activated by CR P on its binding to the phosphocholine groups of microbial phospholipids—and the subsequent interaction of the bound CR P with C1q—to give classical pathway activation, or MBL, or ficolin, binding to arrays of mannose or N-acetyl-glucosamine residues, respectively, on the surfaces of microorganisms—to give lectin pathway activation. Also, in addition to the activation and clearance events associated with complement activation by some of the secreted pattern recognition receptors, it is accepted that all these pattern recognition receptors can generally accelerate the uptake and clearance of microbes via phagocytic cells. In view of the growing interest in the cross-talk between innate and adaptive immunity, a thorough understanding of the initial recognition and triggering events, mediated via innate immune receptors, as addressed in this volume, is clearly very useful in helping to also fully understand the mechanisms of activation and control of the adaptive immune system—and to allow a full assessment of the relative roles played by innate immunity and adaptive immunity against a particular infection in higher organisms.

Bone Cancer

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Author : Dominique Heymann
language : en
Publisher: Academic Press
Release Date : 2021-09-23

Bone Cancer written by Dominique Heymann and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-23 with Medical categories.

Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease. Covers the broad field of bone sarcomas and bone metastases from basic research to clinical approaches Presents comprehensive and translational overview of biological and clinical aspects of bone cancers, discussing pathophysiology from genetic and molecular levels using the most recent evidence Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays