Beta Lactams Natural And Synthetic
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Beta Lactams Natural And Synthetic
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Author : Maghar S. Manhas
language : en
Publisher: John Wiley & Sons
Release Date : 1971
Beta Lactams Natural And Synthetic written by Maghar S. Manhas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medical categories.
Beta Lactams Natural And Synthetic
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Author : Maghar Singh Manhas
language : en
Publisher:
Release Date : 1971
Beta Lactams Natural And Synthetic written by Maghar Singh Manhas and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with categories.
Synthetic Studies Related To Beta Lactam Natural Products
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Author : F. H. S. Hussain
language : en
Publisher:
Release Date : 1985
Synthetic Studies Related To Beta Lactam Natural Products written by F. H. S. Hussain and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.
Beta Lactams
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Author : Bimal K. Banik
language : en
Publisher: Springer
Release Date : 2017-05-11
Beta Lactams written by Bimal K. Banik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-11 with Science categories.
This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Synthesis Of Lactam Antibiotics
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Author : Alle Bruggink
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-27
Synthesis Of Lactam Antibiotics written by Alle Bruggink and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-27 with Science categories.
Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Beta Lactams Natural And Synthetic
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Author : Maghar S. Manhas
language : en
Publisher: John Wiley & Sons
Release Date : 1971
Beta Lactams Natural And Synthetic written by Maghar S. Manhas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medical categories.
New Synthetic Methods For The Synthesis Of Beta Lactam Antibiotics
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Author : J. Knight
language : en
Publisher:
Release Date : 1986
New Synthetic Methods For The Synthesis Of Beta Lactam Antibiotics written by J. Knight and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with categories.
Utilization Of The Beta Lactum Core Towards The Preparation Of Chiral Ring Fused Lactams And Preparation And Application Of Synthetic Peptide Libraries Toward The Discovery And Understanding Of Membrane Permeable Macrocycles
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Author :
language : en
Publisher:
Release Date : 2014
Utilization Of The Beta Lactum Core Towards The Preparation Of Chiral Ring Fused Lactams And Preparation And Application Of Synthetic Peptide Libraries Toward The Discovery And Understanding Of Membrane Permeable Macrocycles written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
The beta-lactam synthon method is an established technique utilizing beta-lactams in natural product synthesis. Through application of our previously described novel beta-lactam preparation, we describe the C3 functionalization and application of previously described and novel beta-lactams towards the synthesis of pactamycin---a densely functionalized cyclopentane natural product---and non-natural analogs of salinosporamide A---a proteasome inhibitor currently in clinical trials for treatment of multiple myeloma.
Penicillins And Cephalosporins
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Author : Robert B. Morin
language : en
Publisher: Academic Press
Release Date : 2014-05-10
Penicillins And Cephalosporins written by Robert B. Morin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Medical categories.
Chemistry and Biology of ?-Lactam Antibiotics, Volume 1: Penicillins and Cephalosporins provides information pertinent to the study of antibiotics containing the ?-lactam moiety. This book discusses the occurrence of a group of ?-lactam antibiotics structurally related to cephalosporin C. Organized into five chapters, this volume begins with an overview of the mechanism of action of ?-lactam antibiotics that caused many microbiologists to develop screening tools for the detection of the ?-lactam moiety. This text then discusses the discovery of the nocardicins, the thienamycins, and olivanic acids. Other chapters provide a summary of the essential penicillin sulfoxide chemistry that gave rise to many compounds. This book discusses as well the ability of chemists to predict the level of biological activity of a compound from knowledge of its structure through theoretical and physicochemical studies. The final chapter deals with quantitative structure–activity relationships. This book is a valuable resource for microbiologists, chemists, and scientists.
Medical Pharmacology And Therapeutics E Book
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Author : Derek G. Waller
language : en
Publisher: Elsevier Health Sciences
Release Date : 2013-08-07
Medical Pharmacology And Therapeutics E Book written by Derek G. Waller and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-07 with Medical categories.
This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice