Biological Chirality
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Progress In Biological Chirality
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Author : Gyula Palyi
language : en
Publisher: Elsevier
Release Date : 2004-12-13
Progress In Biological Chirality written by Gyula Palyi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-13 with Science categories.
Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach to this exciting field, covering a wide range of topics, such as, theory, palaeontology and food technology, to name but a few. This book presents findings via a broad spectrum of scientific approaches making it an excellent overview of Biological Chirality, suitable for postgraduate students, practitioners and researchers in the field of chemistry, biochemistry, biology, palaeontology, and food science with an interest in Chirality. This book contains 32 chapters written by Authors, who are leading authorities in the field Presents the most recent research taking place in this highly challenging field Contains both reference material for the specialist and provides an overview for those who are interested in the fundamental problems of biology and chemistry
Biological Chirality
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Author : Gyula Palyi
language : en
Publisher: Academic Press
Release Date : 2019-11-06
Biological Chirality written by Gyula Palyi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.
Biological Chirality describes this occurrence, its history, and early research around the topic. The work covers analytical methods for observing the phenomenon, providing current techniques and practice and discussing the asymmetric morphology of certain living organisms, such as the position of the heart and liver in humans and the exceptions to biological homochirality seen in D-Amino Acids. In addition, it explores the requirement of enantioselectivity prepared pharmaceuticals to address enantioselectivities biomolecules, a major challenge in today's organic chemistry. Finally, the work considers the possible origin of biological homochirality, as well as the outlook for future research in this area. Describes the history of biological chirality research, its possible origins, and future exploration areas Discusses asymmetric exceptions in morphology and D-Amino Acids Explores the critical implications of enantioselective biomolecules for preparative organic chemistry with a goal of developing effective pharmaceuticals
Chirality And Biological Activity Of Drugs
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Author : Roger J. Crossley
language : en
Publisher: CRC Press
Release Date : 1995-09-11
Chirality And Biological Activity Of Drugs written by Roger J. Crossley and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-09-11 with Medical categories.
This book brings together the theoretical, commercial, and practical aspects of chirality and biological activity of drugs and acts as a ready reference for the effects of enantiomers of drug substances.
Advances In Biochirality
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Author : C. Zucchi
language : en
Publisher: Elsevier
Release Date : 1999-09-08
Advances In Biochirality written by C. Zucchi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-08 with Science categories.
Chirality is a fundamental, persistent, but often overlooked feature of all living organisms on the molecular level as well as on the macroscopic scale. The high degree of preference for only one of two possible mirror image forms in Nature, often called biological homochirality is a puzzling, and not yet fully understood, phenomenon. This book covers biological homochirality from an interdisciplinary approach - contributions range from synthetic chemists, theoretical topologists and physicists, from palaeontologists and biologists to space scientists and representatives of the pharmaceutical and materials industries. Topics covered include - theory of biochirality, origins of biochirality, autocatalysis with amplification of chirality, macroscopic (present) biochirality, fossil records of chiral organisms - paleochirality, extraterrestrial origin of chirality, exceptions to the rule of biological homochirality, D-amino acids, chemical transfer of chirality, PV effects, and polarised radiation chemistry.
Chirality In Biological Nanospaces
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Author : Nilashis Nandi
language : en
Publisher: CRC Press
Release Date : 2011-07-27
Chirality In Biological Nanospaces written by Nilashis Nandi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-27 with Medical categories.
Chirality is widely studied and omnipresent in biological molecules. However, how the retention of enantiomeric forms persists in many life processes without racemization is still unclear, and the molecular understanding of the stringent chiral specificity in enzymatic reactions is sparse. An overview of the influence of chirality in driving reacti
Current Topics In Chirality
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Author : Takashiro Akitsu
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-09-01
Current Topics In Chirality written by Takashiro Akitsu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-01 with Science categories.
Chirality is a concept related not only to organic chemistry but also to each field of natural science. Awareness of hierarchy is important for universal and comprehensive understanding. As such, this book examines myriad subjects related to chirality in chemistry and interdisciplinary applications. In contrast to the previous book, this new book about chirality includes contributions from authors in many fields of natural science, providing a wider overview. The book’s focus is chirality and organic chemistry, including synthesis and reactions.
Chiral Drugs
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Author : Guo-Qiang Lin
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-08
Chiral Drugs written by Guo-Qiang Lin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-08 with Science categories.
An integrated view of chiral drugs from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies asymmetric synthesis, biocatalytic process, and chiral resolution to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective and safer drugs.
Chirality And Biological Activity
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Author : Hartmut Frank
language : en
Publisher: Wiley-Liss
Release Date : 1990
Chirality And Biological Activity written by Hartmut Frank and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Science categories.
Reporting on the latest advances in molecular asymmetry, it explores the development of stereochemical analysis and its applications to the biosciences. Applications to pharmacology and therapeutics, food and beverage chemistry, the study of pesticides and other zenobiotics are also covered. Chapters examine the molecular principles of chiral recognition and biological selectivity and discuss stereoselectivity in drug action and metabolism. Some of the specific issues covered include: gas and liquid chromatography of enantiomers on chiral stationary phases; stereochemical assays of chiral drugs; pyrethroid isomers; configurational modification of peptide hormones; chiral fruit flavors; and human pharmacokinetics of enantiomers administered as racemates.
Asymmetry In Biological Homochirality
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Author : David Hochberg
language : en
Publisher: MDPI
Release Date : 2021-06-04
Asymmetry In Biological Homochirality written by David Hochberg and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-04 with Science categories.
Chirality, or handedness, is a fundamental physical characteristic, which spans the length scales ranging from elementary particles to the chiral asymmetry of spiral galaxies. The way in which chirality in chemistry, or molecular handedness, may have emerged in a primitive terrestrial environment, and how it can be triggered, amplified, and transferred, are deeply challenging problems rooted in both fundamental scientific interests and the technological potentials for science and society. Chirality constitutes a unifying feature of the living world and is a prime driving force for molecular selection and genetic evolution in biology. In this book, we offer a selection of five distinct approaches to this problem by leading experts in the field. The selected topics range from protein chirality and its relevance to protein ageing, protein aggregation and neurodegeneration, entropy production associated with chiral symmetry breaking in closed systems, chiral oscillations in polymerization models involving higher-order oligomers, the mirror symmetry breaking in liquids and its implications for the development of homochirality in abiogenesis, the role of chirality in the chemical sciences, and some philosophical implications of chirality.
Chirality In Biological Nanospaces
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Author :
language : en
Publisher:
Release Date : 2011
Chirality In Biological Nanospaces written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Chirality in Biological Nanospaces: Reactions in Active Sites.