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Biomaterials Degradation


Biomaterials Degradation
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Degradation Phenomena On Polymeric Biomaterials


Degradation Phenomena On Polymeric Biomaterials
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Author : Heinrich Planck
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Degradation Phenomena On Polymeric Biomaterials written by Heinrich Planck and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.


Tradi tionally, the International lTV - Conferences on Biomate rials are focussing on problems in Biomedical Engineering, problems, which are still unsolved, of main interest, and which are of interdisciplinary character. In 1983, the Division of Biomedical Engineering of the Institute of Textile Technology and Chemical Engineering, Denkendorf, started wi th a conference about the use of polyurethanes in biomedicine. Three years later,. in 1986, progress in development and use of polyurethanes was selected as conference topic. It had to be realized that degradation problems were still dominating the discussions. The main discussion topics were: What are the causes for the degradation? How can one prevent them? What are the degradation products, and do they affect the human body? How can one simu late the degradation? How can one accelerate the in vitro tests and how can the results predict the in vivo behaviour of the material? How do in vitro tests correlate with animal tests and the behaviour in the human body? At the third conference in 1989, the speakers focused on the use of textiles in medicine. Again the problem of degradation was discussed intensively and demonstrated by the failure of textile implants, the degradation of aramide polymers or the degradation of resorbable suture materials. The examples make clear, that degradation may be a desired or undesired property of an implant.



Biomaterials Degradation


Biomaterials Degradation
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Author : Mário A. Barbosa
language : en
Publisher: North Holland
Release Date : 1991

Biomaterials Degradation written by Mário A. Barbosa and has been published by North Holland this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


The contributions in this volume provide a critical assessment of the characteristics of common and new biomaterials used in orthopaedic and maxillo-facial surgery, with regard to their resistance to degradation and the associated biological responses of the human body. The topics covered include the properties of metallic, ceramic and polymeric materials, and their applications in modern surgery, particularly in the orthopaedic and dental fields. Their degradation is analysed in detail, from both the negative and positive aspects. Written by eminent scientists from a variety of basic and applied disciplines, the papers will be a useful and dynamic tool for those wishing to increase their knowledge of biomaterials, as well as providing a guide to recent literature in this field."



Degradation Of Implant Materials


Degradation Of Implant Materials
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Author : Noam Eliaz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-08-21

Degradation Of Implant Materials written by Noam Eliaz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-21 with Technology & Engineering categories.


This book reviews the current understanding of the mechanical, chemical and biological processes that are responsible for the degradation of a variety of implant materials. All 18 chapters will be written by internationally renowned experts to address both fundamental and practical aspects of research into the field. Different failure mechanisms such as corrosion, fatigue, and wear will be reviewed, together with experimental techniques for monitoring them, either in vitro or in vivo. Procedures for implant retrieval and analysis will be presented. A variety of biomaterials (stainless steels, titanium and its alloys, nitinol, magnesium alloys, polyethylene, biodegradable polymers, silicone gel, hydrogels, calcium phosphates) and medical devices (orthopedic and dental implants, stents, heart valves, breast implants) will be analyzed in detail. The book will serve as a broad reference source for graduate students and researchers studying biomedicine, corrosion, surface science, and electrochemistry.



Degradation Rate Of Bioresorbable Materials


Degradation Rate Of Bioresorbable Materials
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Author : F J Buchanan
language : en
Publisher: Elsevier
Release Date : 2008-09-26

Degradation Rate Of Bioresorbable Materials written by F J Buchanan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-26 with Technology & Engineering categories.


Bioresorbable materials are extensively used for a wide range of biomedical applications from drug delivery to fracture fixation, and may remain in the body for weeks, months or even years. Accurately predicting and evaluating the degradation rate of these materials is critical to their performance and the controlled release of bioactive agents. Degradation rate of bioresorbable materials provides a comprehensive review of the most important techniques in safely predicting and evaluating the degradation rate of polymer, ceramic and composite based biomaterials. Part one provides an introductory review of bioresorbable materials and the biological environment of the body. Chapters in Part two address degradation mechanisms of commonly used materials such as polymers and ceramics. This is followed by chapters on bioresorption test methods and modelling techniques in Part three. Part four discusses factors influencing bioresorbability such as sterilisation, porosity and host response. The final section reviews current clinical applications of bioresorbable materials. With its distinguished editor and multidisciplinary team of international contributors, Degradation rate of bioresorbable materials: prediction and evaluation provides a unique and valuable reference for biomaterials scientists, engineers and students as well as the medical community. Comprehensively reviews the most pertinent techniques in safely predicting and evaluating the degradation rate of bioresorbable materials Addresses degradation mechanisms of commonly used materials Discusses factors influencing bioresorbability such as sterilisation and host response



Modelling Degradation Of Bioresorbable Polymeric Medical Devices


Modelling Degradation Of Bioresorbable Polymeric Medical Devices
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Author : J Pan
language : en
Publisher: Elsevier
Release Date : 2014-10-24

Modelling Degradation Of Bioresorbable Polymeric Medical Devices written by J Pan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-24 with Technology & Engineering categories.


The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates



Biodegradable Metals


Biodegradable Metals
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Author : Hendra Hermawan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-15

Biodegradable Metals written by Hendra Hermawan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-15 with Technology & Engineering categories.


This book in the emerging research field of biomaterials covers biodegradable metals for biomedical applications. The book contains two main parts where each of them consists of three chapters. The first part introduces the readers to the field of metallic biomaterials, exposes the state of the art of biodegradable metals, and reveals its application for cardiovascular implants. Some fundamental aspects to give basic understanding on metals for further review on the degradable ones is covered in chapter one. The second chapter introduces the concept of biodegradable metals, it's state of the art and discuses a shifted paradigm from inert to bioactive, from corrosion resistant to corrodible metals. The third chapter focuses on the challenges and opportunities of using biodegradable metals for cardiovascular applications. The second part exposes an example of biodegradable metals from its concept to applications where a complete study on metallic biodegradable stent is detailed from materials design, development, testing till the implant fabrication. The forth chapter reveals new alloys development devoted for metallic biodegradable stent based on required criteria derrived from clinical needs and current nondegradable stents properties. Degradation of the alloys in simulated arterial conditions and its effect to cells are exposed in chapter five. The both chapters are concluded with a benchmarking of some more recent researches on materials development and testing for biodegradable stents. Chapter six reveals the tranformation process of the materials into stent prototypes where a standard process for making 316L stainless steel stents was followed. The book is completed by a perspective on the use of biodegradable metals for biomedical applications in the era of tissue engineering.



Degradable Materials


Degradable Materials
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Author : Sumner A. Barenberg
language : en
Publisher: CRC Press
Release Date : 2018-01-18

Degradable Materials written by Sumner A. Barenberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Technology & Engineering categories.


This book addresses the fields of biodegradation, environmental degradation, and photochemical degradation. The purpose of the book is to establish guidelines for terminology, nomenclature, characterization techniques and methodology, mechanisms of degradation, standard reference materials, and issues and needs. This is the first scientific book of this nature based on the findings of the world's leading scientists (academic, industrial, and federal) in this field. Hard data is presented and soft data is identified under issues and needs. New areas covered are such topics as: biodegradation with in vivo applications, environmental degradation, including anaerobic, aerobic, characterization techniques and methodology, photochemical degradation, and secondary issues associated with degradation. This publication contains information vital to environmental scientists and engineers, biomaterials scientists, pharmaceutical technologists, and chemists.



A Phenomenological Mathematical Modelling Framework For The Degradation Of Bioresorbable Composites


A Phenomenological Mathematical Modelling Framework For The Degradation Of Bioresorbable Composites
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Author : Ismael Moreno-Gomez
language : en
Publisher: Springer
Release Date : 2019-04-05

A Phenomenological Mathematical Modelling Framework For The Degradation Of Bioresorbable Composites written by Ismael Moreno-Gomez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-05 with Technology & Engineering categories.


This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation. Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.



Natural And Synthetic Biomedical Polymers


Natural And Synthetic Biomedical Polymers
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Author : Sangamesh G. Kum bar
language : en
Publisher: Newnes
Release Date : 2014-01-21

Natural And Synthetic Biomedical Polymers written by Sangamesh G. Kum bar and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-21 with Technology & Engineering categories.


Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future



Advances In Biomaterials Science And Biomedical Applications


Advances In Biomaterials Science And Biomedical Applications
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Author : Rosario Pignatello
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-03-27

Advances In Biomaterials Science And Biomedical Applications written by Rosario Pignatello and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-27 with Technology & Engineering categories.


This contribution book is a collection of reviews and original articles from eminent experts working in the multi- and interdisciplinary arena of biomaterials, ranging from their design to novel uses. From their personal experience, the readers can obtain a stimulating foresight on the potentialities of different synthetic and engineered biomaterials. 21 chapters have been organized to illustrate different aspects of biomaterials science. From advanced means for the characterization and toxicological assessment of new materials, through "classical" applications in nanotechnology and tissue engineering, toward novel specific uses of these products, the volume wishes to give readers a view of the wide range of disciplines and methodologies that have been exploited to develop biomaterials with the physical and biological features needed for specific clinical and medical applications.