Biomechanical Behavior Of Human Atherosclerotic Plaque
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Biomechanical Behavior Of Human Atherosclerotic Plaque
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Author : Nitin Vishwasrao Salunke
language : en
Publisher:
Release Date : 1996
Biomechanical Behavior Of Human Atherosclerotic Plaque written by Nitin Vishwasrao Salunke and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Atherosclerosis categories.
Biomechanics Of Coronary Atherosclerotic Plaque
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-03-15
Biomechanics Of Coronary Atherosclerotic Plaque written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-15 with Science categories.
Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, First Edition, is the first comprehensive text to focus on important biomechanical studies conducted in the last decade that have increased our understanding of coronary atherosclerotic plaque initiation, growth, and rupture, as well as improving the design of medical devices and clinical interventions, including surgical procedures. The book provides students, researchers, engineers, clinicians, and interventional cardiologists with an overview of the main topics related to the biomechanics of atherosclerosis, in a single volume written by several experts in the field. This volume is part of the Biomechanics of Living Organs book series. The biomechanics of human soft tissues and organs has been an emerging research field since the publication of Y.C. Fung’s original book series in the 1990s. The publication of such books entirely dedicated to a specific biomechanical subject is necessary to advance scientific research in the field of biomechanics and to transfer important knowledge to future generations. Therefore, this series of volumes on the biomechanics of living organs has been created. This series began in July 2017 with the publication of a first volume on the fundamentals of Hyperelastic Constitutive Laws for Finite Element Modeling of Living Organs. The current volume on the Biomechanics of Coronary Atherosclerotic Plaque, is the latest in this new series. Presents the main computational fluid dynamic studies performed, describing blood flow in healthy and pathological artery branches, including in coronary bifurcations Highlights the correlation between plaque initiation regions and blood shear stress amplitude Discusses the main biomechanical and mechanobiological models to highlight the importance of quantifying the residual and peak cap stresses and the presence of μ-calcifications to evaluate the risk of plaque rupture Introduces the most recent intravascular imaging biomarker techniques (elastography, palpography and modulography)
Biomechanical Characterization Of Atherosclerotic Plaques
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Author : Donna Michelle Ebenstein
language : en
Publisher:
Release Date : 2002
Biomechanical Characterization Of Atherosclerotic Plaques written by Donna Michelle Ebenstein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
Plaque Erosion And Murine Plaque Stability
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Author : Ian Christopher Campbell
language : en
Publisher:
Release Date : 2013
Plaque Erosion And Murine Plaque Stability written by Ian Christopher Campbell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Atherosclerotic plaque categories.
Atherosclerotic plaque disruption leading to thrombosis has traditionally been studied as a rupture of a thin fibrous cap over a lipid-laden necrotic core. However, two noteworthy categories of plaques that do not rupture have presented themselves: 1) in mice, plaque rupture is rare if not absent, and 2) in humans, some plaques erode and form a thrombus without rupturing. Current understanding of the biomechanical differences between plaques that rupture and those that do not is incomplete. In this research, we used patient-specific computational biomechanics tools to study differences among these groups. Lesion-specific solid mechanical modeling of murine plaques revealed that the relative distribution of stresses differs considerably between mice and man. In human vulnerable plaques, peak stresses are on the thin fibrous cap over a necrotic core, but in mice the highest stresses are in the media and adventitia, away from the plaque. Whereas atherosclerotic human arteries usually experience neointima formation around the entire circumference of the vessel, mouse plaques tend to be punctate and adjacent lesion-free regions. The difference in mechanical environment suggests that plaque rupture, if possible in mice, is likely not driven by mechanics in the same manner as humans. Similar mechanical modeling of human ruptured and eroded plaques and comparison to histological staining revealed that ruptured plaques exhibit increased levels of inflammatory markers in response to strain in ruptured plaques, but no such response was observed in plaque erosion. This suggests that treatment of inflammation, a current paradigm for care of atherosclerotic patients, may not be an effective approach to mediate plaque erosion. Computational fluid dynamics modeling of patients with plaque erosion revealed no relation between wall shear stress magnitude or direction, further suggesting that the mechanism of plaque erosion differs considerably from that of plaque rupture. Together, these findings suggest that biomechanics can help explain why not all plaques rupture and that different clinical approaches are necessary to address different phenotypes of lesions.
Panvascular Medicine
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Author : Peter Lanzer
language : en
Publisher: Springer
Release Date : 2015-03-30
Panvascular Medicine written by Peter Lanzer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-30 with Medical categories.
Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.
Biomechanics Of Soft Tissue In Cardiovascular Systems
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Author : Gerhard A. Holzapfel
language : en
Publisher: Springer
Release Date : 2014-05-04
Biomechanics Of Soft Tissue In Cardiovascular Systems written by Gerhard A. Holzapfel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-04 with Technology & Engineering categories.
The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.
Atherosclerotic Plaque Characterization Methods Based On Coronary Imaging
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Author : Lambros S Athanasiou
language : en
Publisher: Academic Press
Release Date : 2017-05-04
Atherosclerotic Plaque Characterization Methods Based On Coronary Imaging written by Lambros S Athanasiou and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-04 with Technology & Engineering categories.
Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging provides a complete review of computer methods for atherosclerotic plaque reconstruction and characterization. The authors, with their expertise from biomedical engineering, computer science, and cardiology, offer a holistic view. The focus of the book is on the presentation of major imaging techniques, including their limitations. It includes details on the mechanical characterization and properties of plaques and appropriate constitutive models to describe the mechanical behavior of plaques. The authors explore the challenges of using multiple coronary imaging technologies, and provide the pros and cons of invasive vs. non-invasive techniques. Methods for plaque characterization and 3D reconstruction of coronary arteries using IVUS, OCT, and CT images are described. This book will help readers study new trends in image processing analysis and plaque characterization, implement automated plaque characterization methodologies, understand coronary imaging drawbacks, and comprehend 3 dimensional coronary artery and plaque reconstruction methods. Describes the multimodality imaging techniques that are commonly used in the diagnosis of arterial diseases, including intravascular ultrasound, optical coherence tomography, angiography, computed tomography angiography, and magnetic resonance angiography Discusses in-depth the computational methods which can be used for the detection of different plaque types Explores plaque in 3D reconstruction methods and plaque modeling approaches
The Vulnerable Atherosclerotic Plaque
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Author : Renu Virmani
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
The Vulnerable Atherosclerotic Plaque written by Renu Virmani and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.
Finally, a convenient, one-volume summary of current knowledge on an area of increasing importance! The Vulnerable Atherosclerotic Plaque presents contributions from the best investigators in the field, skillfully edited for easy reading and lavishly illustrated with high-quality, full-color images. After a considered and concise introduction, the book concentrates on: Pathology of vulnerable plaque Triggers for plaque rupture Imaging of unstable plaque Management of vulnerable plaques Careful editing allows the authors to avoid repetition and provide comprehensive coverage of pathology, detection, and management. This thorough and authoritative reference will change the way interventionists look at the disease.
Pan Vascular Medicine
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Author : Peter Lanzer
language : en
Publisher: Springer
Release Date : 2013-12-20
Pan Vascular Medicine written by Peter Lanzer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-20 with Medical categories.
The textbook provides an interdisciplinary and integrated perspective of modern vascular cure. Written by experts the text proceeds from fundamental principles to advanced concepts. The book is divided into four parts, each focusing on different basic concepts of vascular cure. All fundamental principles of the area are clearly explained to facilitate vascular diagnostics and treatment in clinical practice. It is aimed at junior practitioners and experts.
Biomechanics Of Living Organs
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Author : Yohan Payan
language : en
Publisher: World Bank Publications
Release Date : 2017-06-09
Biomechanics Of Living Organs written by Yohan Payan and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-09 with Medical categories.
Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling is the first book to cover finite element biomechanical modeling of each organ in the human body. This collection of chapters from the leaders in the field focuses on the constitutive laws for each organ. Each author introduces the state-of-the-art concerning constitutive laws and then illustrates the implementation of such laws with Finite Element Modeling of these organs. The focus of each chapter is on instruction, careful derivation and presentation of formulae, and methods. When modeling tissues, this book will help users determine modeling parameters and the variability for particular populations. Chapters highlight important experimental techniques needed to inform, motivate, and validate the choice of strain energy function or the constitutive model. Remodeling, growth, and damage are all covered, as is the relationship of constitutive relationships of organs to tissue and molecular scale properties (as net organ behavior depends fundamentally on its sub components). This book is intended for professionals, academics, and students in tissue and continuum biomechanics. Covers hyper elastic frameworks for large tissue deformations Considers which strain energy functions are the most appropriate to model the passive and active states of living tissue Evaluates the physical meaning of proposed energy functions